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RN7SK and HMGA1
Number of citations of the paper that reports this interaction (PMID
21087998
)
9
Data Source:
BioGRID
(unspecified method)
RN7SK
HMGA1
Gene Name
RNA, 7SK small nuclear
high mobility group AT-hook 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Transcription Factor Complex
Cytosol
Focal Adhesion
Senescence-associated Heterochromatin Focus
Molecular Function
DNA Binding
AT DNA Binding
DNA-(apurinic Or Apyrimidinic Site) Lyase Activity
Protein Binding
Transcription Factor Binding
Enzyme Binding
Ligand-dependent Nuclear Receptor Transcription Coactivator Activity
Retinoic Acid Receptor Binding
Peroxisome Proliferator Activated Receptor Binding
Retinoid X Receptor Binding
5'-deoxyribose-5-phosphate Lyase Activity
Biological Process
DNA Catabolic Process, Endonucleolytic
DNA Unwinding Involved In DNA Replication
Base-excision Repair
Nucleosome Disassembly
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Protein Complex Assembly
Negative Regulation Of Cell Proliferation
Response To Virus
Viral Process
Negative Regulation Of Chromatin Silencing
Senescence-associated Heterochromatin Focus Assembly
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Establishment Of Integrated Proviral Latency
Oncogene-induced Cell Senescence
Positive Regulation Of Cellular Senescence
Pathways
DNA Damage/Telomere Stress Induced Senescence
Vpr-mediated nuclear import of PICs
HIV Infection
Cellular Senescence
Host Interactions of HIV factors
Integration of provirus
Interactions of Vpr with host cellular proteins
Early Phase of HIV Life Cycle
Autointegration results in viral DNA circles
HIV Life Cycle
Formation of Senescence-Associated Heterochromatin Foci (SAHF)
2-LTR circle formation
Integration of viral DNA into host genomic DNA
APOBEC3G mediated resistance to HIV-1 infection
Drugs
Diseases
GWAS
Body mass index (
20935630
)
Height (
21998595
20881960
19396169
19343178
19893584
23563607
18391951
20397748
20189936
)
Protein-Protein Interactions
6 interactors:
CCNT1
CDK9
HEXIM1
HMGA1
LARP7
MEPCE
60 interactors:
ANXA1
ANXA2
APEX1
ATF2
CDK1
CEBPB
CREBBP
CSNK2A1
CSNK2A2
CWC27
DNAJC8
EIF2S2
ELF1
EWSR1
GTF2F2
HIPK2
HMGB1
HMGB2
HMGB3
HNRNPA1
HNRNPAB
HNRNPD
HNRNPDL
HNRNPL
HSPA1A
IRF1
JUN
KAT2B
METAP2
NCL
NFKB1
NFYA
NPM1
OLA1
ORC6
PA2G4
PARP1
PCBP1
PCBP2
POU2F1
POU2F2
POU3F1
PPARG
PPP1R8
PRKCA
PRMT6
PSIP1
PTBP1
RARA
RARG
RCC1
RN7SK
RNF4
RXRA
SP1
SRF
SSB
SUFU
SYNCRIP
UPF2
Entrez ID
125050
3159
HPRD ID
02829
Ensembl ID
ENSG00000202198
ENSG00000137309
Uniprot IDs
P17096
Q5T6U8
PDB IDs
2EZD
2EZE
2EZF
2EZG
Enriched GO Terms of Interacting Partners
?
RNA Metabolic Process
Regulation Of Cell Cycle
Positive Regulation Of Viral Transcription
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Transcription Elongation From RNA Polymerase II Promoter
Regulation Of Viral Transcription
Positive Regulation Of Viral Process
Negative Regulation Of Biosynthetic Process
Nitrogen Compound Metabolic Process
DNA-templated Transcription, Elongation
Viral Process
SnRNA Modification
Replication Fork Arrest
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
DNA-dependent DNA Replication
Gene Expression
Regulation Of Transcription From RNA Polymerase II Promoter
Oncogene-induced Cell Senescence
Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Viral Process
Senescence-associated Heterochromatin Focus Assembly
Transcription Initiation From RNA Polymerase II Promoter
Negative Regulation Of Cellular Metabolic Process
Cellular Response To Transforming Growth Factor Beta Stimulus
Response To Transforming Growth Factor Beta
Positive Regulation Of Cellular Senescence
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Transcription, DNA-templated
Regulation Of RNA Metabolic Process
RNA Biosynthetic Process
DNA-templated Transcription, Initiation
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Negative Regulation Of Chromatin Binding
Negative Regulation Of Chromatin Silencing
Negative Regulation Of Transcription, DNA-templated
Establishment Of Integrated Proviral Latency
Regulation Of Gene Expression
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
DNA Replication
Positive Regulation Of Cell Aging
Establishment Of Viral Latency
Heterochromatin Assembly
Negative Regulation Of Gene Expression
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Gene Expression
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
RNA Metabolic Process
Nitrogen Compound Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Cellular Metabolic Process
Regulation Of Gene Expression
Transcription, DNA-templated
Regulation Of RNA Metabolic Process
RNA Biosynthetic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of RNA Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Metabolic Process
Transcription From RNA Polymerase II Promoter
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Metabolic Process
Cellular Metabolic Process
Negative Regulation Of Cellular Metabolic Process
MRNA Metabolic Process
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Nucleic Acid-templated Transcription
MRNA Splicing, Via Spliceosome
Negative Regulation Of RNA Biosynthetic Process
RNA Splicing, Via Transesterification Reactions
Negative Regulation Of Gene Expression
RNA Splicing
Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
RNA Processing
Transcription Initiation From RNA Polymerase II Promoter
MRNA Processing
Regulation Of Cell Cycle
Viral Process
Cell Differentiation
Metabolic Process
DNA-templated Transcription, Initiation
Cellular Response To Organic Substance
Developmental Process
Regulation Of Cell Differentiation
Tagcloud
?
arresting
attribute
augments
bcl2
concomitantly
e2
e6
evidences
g0
galactosidase
hmgb1
hpv16
htert
kb
linking
mechanistic
messaging
papilloma
re
senescence
senescent
sensitizes
shifted
siha
survivin
sustaining
tendency
tnf
tumorigenesis
Tagcloud (Difference)
?
arresting
attribute
augments
bcl2
concomitantly
e2
e6
evidences
g0
galactosidase
hmgb1
hpv16
htert
kb
linking
mechanistic
messaging
papilloma
re
senescence
senescent
sensitizes
shifted
siha
survivin
sustaining
tendency
tnf
tumorigenesis
Tagcloud (Intersection)
?