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RN7SK and CCNT1
Number of citations of the paper that reports this interaction (PMID
15201869
)
87
Data Source:
BioGRID
(two hybrid)
RN7SK
CCNT1
Gene Name
RNA, 7SK small nuclear
cyclin T1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Positive Transcription Elongation Factor Complex B
Molecular Function
DNA Binding
Chromatin Binding
Protein Binding
SnRNA Binding
Protein Kinase Binding
Transcription Regulatory Region DNA Binding
Biological Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Transcription, DNA-templated
Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
Protein Phosphorylation
Cell Cycle
Transforming Growth Factor Beta Receptor Signaling Pathway
Gene Expression
Viral Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Viral Transcription
Cell Division
Pathways
Loss of Function of TGFBR2 in Cancer
Formation of HIV-1 elongation complex containing HIV-1 Tat
RNA Polymerase II Transcription
HIV Infection
SMAD2/3 MH2 Domain Mutants in Cancer
Tat-mediated elongation of the HIV-1 transcript
Tat-mediated HIV elongation arrest and recovery
TGFBR1 LBD Mutants in Cancer
RNA Polymerase II Pre-transcription Events
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
HIV elongation arrest and recovery
HIV Life Cycle
Generic Transcription Pathway
HIV Transcription Elongation
TGFBR2 MSI Frameshift Mutants in Cancer
SMAD2/3 Phosphorylation Motif Mutants in Cancer
Loss of Function of SMAD2/3 in Cancer
TGFBR2 Kinase Domain Mutants in Cancer
Host Interactions of HIV factors
Loss of Function of SMAD4 in Cancer
Interactions of Tat with host cellular proteins
TGFBR1 KD Mutants in Cancer
Pausing and recovery of Tat-mediated HIV elongation
Loss of Function of TGFBR1 in Cancer
Late Phase of HIV Life Cycle
Formation of RNA Pol II elongation complex
Signaling by TGF-beta Receptor Complex
Signaling by TGF-beta Receptor Complex in Cancer
Pausing and recovery of HIV elongation
Formation of HIV elongation complex in the absence of HIV Tat
Transcription of the HIV genome
SMAD4 MH2 Domain Mutants in Cancer
RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Protein-Protein Interactions
6 interactors:
CCNT1
CDK9
HEXIM1
HMGA1
LARP7
MEPCE
26 interactors:
AFF4
AHR
BRD4
CDK9
CTD
ESR1
GRIPAP1
GRN
GTF2F1
HEXIM1
HEXIM2
HIC2
HTATSF1
HTN1
KAT2B
MBP
MDFIC
MYC
NCOA2
NUFIP1
PML
POLR2A
PURA
RN7SK
SKP2
SUPT5H
Entrez ID
125050
904
HPRD ID
03938
Ensembl ID
ENSG00000202198
ENSG00000129315
Uniprot IDs
A8K4M5
A9XU13
O60563
PDB IDs
2PK2
3BLH
3BLQ
3BLR
3LQ5
3MI9
3MIA
3MY1
3TN8
3TNH
3TNI
4BCF
4BCG
4BCH
4BCI
4BCJ
4EC8
4EC9
4IMY
Enriched GO Terms of Interacting Partners
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RNA Metabolic Process
Regulation Of Cell Cycle
Positive Regulation Of Viral Transcription
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Transcription Elongation From RNA Polymerase II Promoter
Regulation Of Viral Transcription
Positive Regulation Of Viral Process
Negative Regulation Of Biosynthetic Process
Nitrogen Compound Metabolic Process
DNA-templated Transcription, Elongation
Viral Process
SnRNA Modification
Replication Fork Arrest
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
DNA-dependent DNA Replication
Gene Expression
Regulation Of Transcription From RNA Polymerase II Promoter
Oncogene-induced Cell Senescence
Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Viral Process
Senescence-associated Heterochromatin Focus Assembly
Transcription Initiation From RNA Polymerase II Promoter
Negative Regulation Of Cellular Metabolic Process
Cellular Response To Transforming Growth Factor Beta Stimulus
Response To Transforming Growth Factor Beta
Positive Regulation Of Cellular Senescence
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Transcription, DNA-templated
Regulation Of RNA Metabolic Process
RNA Biosynthetic Process
DNA-templated Transcription, Initiation
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Negative Regulation Of Chromatin Binding
Negative Regulation Of Chromatin Silencing
Negative Regulation Of Transcription, DNA-templated
Establishment Of Integrated Proviral Latency
Regulation Of Gene Expression
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
DNA Replication
Positive Regulation Of Cell Aging
Establishment Of Viral Latency
Heterochromatin Assembly
Negative Regulation Of Gene Expression
Transcription, DNA-templated
RNA Biosynthetic Process
RNA Metabolic Process
Gene Expression
Cellular Macromolecule Biosynthetic Process
Regulation Of Transcription, DNA-templated
Macromolecule Biosynthetic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Positive Regulation Of Viral Transcription
Cellular Aromatic Compound Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Viral Process
Cellular Nitrogen Compound Metabolic Process
Transcription From RNA Polymerase II Promoter
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Regulation Of Viral Transcription
Regulation Of Viral Process
Positive Regulation Of Viral Process
Positive Regulation Of Cellular Biosynthetic Process
Nitrogen Compound Metabolic Process
Biosynthetic Process
Transcription Initiation From RNA Polymerase II Promoter
Negative Regulation Of Gene Expression
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Biosynthetic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
DNA-templated Transcription, Initiation
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Regulation Of DNA-templated Transcription, Elongation
Negative Regulation Of Cell Cycle
Transcription Elongation From RNA Polymerase II Promoter
Chromatin Remodeling
DNA-templated Transcription, Elongation
Regulation Of Metabolic Process
Regulation Of Cell Cycle
Positive Regulation Of DNA-templated Transcription, Elongation
Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
7-methylguanosine MRNA Capping
Positive Regulation Of Metabolic Process
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