MRPL10 and PNMA1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MRPL10	PNMA1
Gene Name		mitochondrial ribosomal protein L10	paraneoplastic Ma antigen 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit Ribonucleoprotein Complex	Nucleolus Cytoplasm Focal Adhesion
	Molecular Function	Structural Constituent Of Ribosome Poly(A) RNA Binding	Protein Binding
	Biological Process	Translation Organelle Organization Mitochondrial Translation Ribosome Biogenesis Mitochondrial Translational Initiation Mitochondrial Translational Elongation Mitochondrial Translational Termination	Inflammatory Response To Antigenic Stimulus Positive Regulation Of Apoptotic Process
Pathways		Mitochondrial translation Organelle biogenesis and maintenance Mitochondrial translation elongation Mitochondrial translation initiation Mitochondrial translation termination
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033)
Protein-Protein Interactions		7 interactors: APP FAM9B KLHL12 PNMA1 REL TCF4 USP22	114 interactors: ANKRD36BP1 APTX ARID5A ASMTL ATP5O ATXN7 BEX2 BYSL C14orf105 C21orf58 C5orf30 C8orf33 CARHSP1 CCDC146 CCDC33 CCNG1 CCP110 CDK18 CFAP53 CHIC2 CHMP2B CNNM3 COX5B DCTN4 EHHADH ENKD1 FAM107A FAM110A FBF1 FBXL18 FEM1C FMNL2 GEM GPANK1 GPR25 GTPBP10 HDAC4 HOXB9 INO80B KANSL1 KAT2B LENG1 LIN37 MAB21L2 MARK4 MCM7 MED8 METTL17 MRPL10 MRPL11 MRPL23 MSI1 NPBWR2 NUDT16L1 PARD3 PARD6B PIN1 PIN4 PNMA5 PNMA6A POLDIP3 POLL POLM PRKCG PRKCI PRPF31 PSMA1 RAPGEF3 RBM41 RPP25L RSPH9 RSRC2 RTP5 RUSC1 SCAND1 SCNM1 SDCBP SEMA4C SH2D4A SHISA3 SLC25A48 SLIRP SMIM3 SNRPB SNRPB2 SPATC1L SPG7 STAMBPL1 SUV39H2 TCEANC TEAD4 TMSB4X TNNI1 TNNT1 TRIM42 TRPV6 TSPYL4 TTC9C TXNDC9 UBQLN1 UBQLN4 URB1-AS1 USP2 VAV2 VBP1 WDR25 WDYHV1 WT1-AS ZC2HC1C ZCCHC12 ZFYVE26 ZG16B ZNF564 ZNF581
Entrez ID		124995	9240
HPRD ID		14738	04926
Ensembl ID		ENSG00000159111	ENSG00000176903
Uniprot IDs		Q7Z7H8	Q8ND90
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Mitotic Cell Cycle Synaptic Growth At Neuromuscular Junction Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Catenin Import Into Nucleus Regulation Of Protein Binding Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Collateral Sprouting In Absence Of Injury Regulation Of Protein Metabolic Process Maintenance Of DNA Repeat Elements Negative Regulation Of Wnt Signaling Pathway Regulation Of Cell Cycle Vesicle Localization Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Canonical Wnt Signaling Pathway Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Embryonic Hindgut Morphogenesis Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Axon Choice Point Recognition Embryonic Genitalia Morphogenesis Positive Regulation Of Cellular Metabolic Process Regulation Of Binding Myoblast Fate Commitment Wnt Signaling Pathway Positive Regulation Of Cell Cycle Regulation Of Developmental Growth Neuron Remodeling Secretory Granule Localization Regulation Of Signal Transduction Regulation Of Wnt Signaling Pathway Positive Regulation Of Protein Metabolic Process Hindgut Morphogenesis Immune Response Insulin Metabolic Process Positive Regulation Of Interleukin-12 Biosynthetic Process Defense Response Hindgut Development Regulation Of Signaling Positive Regulation Of Protein Export From Nucleus Positive Regulation Of Glycoprotein Biosynthetic Process Positive Regulation Of Triglyceride Biosynthetic Process RNA Metabolic Process Positive Regulation Of Glycoprotein Metabolic Process Regulation Of Interleukin-12 Biosynthetic Process	Cell Cycle Apical Junction Assembly Organelle Organization Histone H3-K9 Modification
Tagcloud ?		15k cdnas characters clustering developmentally dncic2 dosage ds eef1g eif3sf extra hchr21 hierarchical manifested mrps18a neurogenesis neuron neuropathological outgrowth patterned peg3 phenotypic retardation sf3a60 snapc3 srprb syngr2 tt2f ubce8	adenocarcinoma apoptotic autoimmune bcl besides closely commonly decreases ductal erk expanding find mapk member neurological pancreatic paraneoplastic pdac pi3k pns pro promotes represent reveal suppression testis viability widely
Tagcloud (Difference) ?		15k cdnas characters clustering developmentally dncic2 dosage ds eef1g eif3sf extra hchr21 hierarchical manifested mrps18a neurogenesis neuron neuropathological outgrowth patterned peg3 phenotypic retardation sf3a60 snapc3 srprb syngr2 tt2f ubce8	adenocarcinoma apoptotic autoimmune bcl besides closely commonly decreases ductal erk expanding find mapk member neurological pancreatic paraneoplastic pdac pi3k pns pro promotes represent reveal suppression testis viability widely
Tagcloud (Intersection) ?