CLNS1A and LSM10

Number of citations of the paper that reports this interaction (PubMedID 16087681)
0

Data Source:
BioGRID (pull down, affinity chromatography technology)

		CLNS1A	LSM10
Description		chloride nucleotide-sensitive channel 1A	LSM10, U7 small nuclear RNA associated
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cilium Methylosome PICln-Sm Protein Complex	Nucleus Nucleoplasm U7 SnRNP Cajal Body Nuclear Body Cytoplasmic U SnRNP Body Ribonucleoprotein Complex
	Molecular Function	RNA Binding Protein Binding	RNA Binding Protein Binding Histone Pre-mRNA DCP Binding U7 SnRNA Binding
	Biological Process	Spliceosomal SnRNP Assembly MRNA Processing Chloride Transport Cell Volume Homeostasis RNA Splicing MRNA Cis Splicing, Via Spliceosome Positive Regulation Of MRNA Splicing, Via Spliceosome	MRNA Processing MRNA 3'-end Processing By Stem-loop Binding And Cleavage RNA Splicing Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		snRNP Assembly	SLBP independent Processing of Histone Pre-mRNAs RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653) Platelet distribution width ( 32888494) Tourette syndrome ( 30818990)	Diverticulitis ( 28585551) Neutrophil count ( 29403010)
Interacting Genes		14 interacting genes: ACTB CSNK2A1 EIF4A2 EPB41 EPB41L3 FRMD7 ITGA2B LARP1 LSM10 PRMT5 SNRPB SNRPD1 UBC WDR77	10 interacting genes: BMPR2 CLNS1A LSM11 LSM3 MIR10B MIR128-1 MIR20A MIRLET7A1 SLBP SMN1
Entrez ID		1207	84967
HPRD ID		03694	14326
Ensembl ID		ENSG00000074201	ENSG00000181817
Uniprot IDs		E9PJF4 E9PMI6 J3KN38 P54105	Q969L4
PDB IDs		6V0O 9E3A 9E3B	6V4X
Enriched GO Terms of Interacting Partners?		Methylosome Spliceosomal SnRNP Assembly Histone Pre-mRNA DCP Binding U7 SnRNP U1 SnRNP Binding Protein-RNA Complex Assembly 7-methylguanosine Cap Hypermethylation Regulation Of Dopamine Receptor Signaling Pathway U4 SnRNP Structural Constituent Of Cytoskeleton Small Nuclear Ribonucleoprotein Complex Regulation Of Translational Initiation SMN-Sm Protein Complex Macromolecule Methylation U1 SnRNP U5 SnRNP Cytosol U2-type Prespliceosome Assembly U12-type Spliceosomal Complex Regulation Of Protein Localization To Cell Periphery Cortical Cytoskeleton Ribonucleoprotein Complex Cortical Actin Cytoskeleton Organization U2-type Spliceosomal Complex U2-type Catalytic Step 2 Spliceosome U2 SnRNP Methyl-CpG Binding Positive Regulation Of MRNA Splicing, Via Spliceosome Protein Methylation U4/U6 X U5 Tri-snRNP Complex Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Response To Environmental Enrichment Negative Regulation Of Translational Initiation Negative Regulation Of RNA-dependent RNA Polymerase Activity Cortical Cytoskeleton Organization Spliceosomal Complex Assembly U2-type Precatalytic Spliceosome Methylation Positive Regulation Of RNA Splicing Positive Regulation Of Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Oocyte Axis Specification Cytoplasmic U SnRNP Body RNA Binding Protein Metabolic Process MRNA Metabolic Process Regulation Of Norepinephrine Uptake Swimming Behavior Cytoskeletal Protein Binding U2 SnRNP Binding	MiRNA-mediated Gene Silencing By Inhibition Of Translation MRNA Base-pairing Post-transcriptional Repressor Activity RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Positive Regulation Of MRNA Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Cell Proliferation Involved In Heart Morphogenesis Regulatory NcRNA-mediated Gene Silencing MRNA Processing Negative Regulation Of Translation Regulation Of Cell Migration Involved In Sprouting Angiogenesis MRNA 3'-end Processing By Stem-loop Binding And Cleavage Histone Pre-mRNA 3'end Processing Complex MRNA Metabolic Process MRNA Destabilization RNA Destabilization Regulation Of MRNA Metabolic Process Positive Regulation Of MRNA Catabolic Process Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Cell Proliferation Involved In Heart Morphogenesis MRNA 3'-UTR Binding RNA Processing Regulation Of Translation Histone MRNA Metabolic Process Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Cell Migration Regulation Of Cell Motility MRNA 3'-end Processing Regulation Of Endothelial Cell Migration Regulation Of MRNA Stability Regulation Of Locomotion RNA Splicing, Via Transesterification Reactions Regulation Of RNA Stability Negative Regulation Of Protein Metabolic Process Post-transcriptional Regulation Of Gene Expression Spliceosomal SnRNP Assembly Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Outflow Tract Morphogenesis Negative Regulation Of Lipoprotein Transport Negative Regulation Of Cardioblast Proliferation RNA Metabolic Process Negative Regulation Of Cell Migration Negative Regulation Of Endothelial Cell Migration Positive Regulation Of Osteoblast Differentiation Extracellular Space Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility
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