CLNS1A and FRMD7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CLNS1A	FRMD7
Description		chloride nucleotide-sensitive channel 1A	FERM domain containing 7
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cilium Methylosome PICln-Sm Protein Complex	Extracellular Space Nucleoplasm Cytosol Plasma Membrane Growth Cone Cell Projection Neuron Projection Neuronal Cell Body
	Molecular Function	RNA Binding Protein Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Spliceosomal SnRNP Assembly MRNA Processing Chloride Transport Cell Volume Homeostasis RNA Splicing MRNA Cis Splicing, Via Spliceosome Positive Regulation Of MRNA Splicing, Via Spliceosome	Nervous System Development Positive Regulation Of Lamellipodium Assembly Regulation Of Neuron Projection Development Positive Regulation Of Small GTPase Mediated Signal Transduction Negative Regulation Of Stress Fiber Assembly
Pathways		snRNP Assembly
Drugs
Diseases			Congenital motor nystagmus (CMN); Idiopathic congenital nystagmus (ICN)
GWAS		Diastolic blood pressure ( 30224653) Platelet distribution width ( 32888494) Tourette syndrome ( 30818990)	Gestational age at birth (maternal effect) ( 28877031) Heel bone mineral density ( 30598549)
Interacting Genes		14 interacting genes: ACTB CSNK2A1 EIF4A2 EPB41 EPB41L3 FRMD7 ITGA2B LARP1 LSM10 PRMT5 SNRPB SNRPD1 UBC WDR77	1 interacting genes: CLNS1A
Entrez ID		1207	90167
HPRD ID		03694	06624
Ensembl ID		ENSG00000074201	ENSG00000165694
Uniprot IDs		E9PJF4 E9PMI6 J3KN38 P54105	Q6ZUT3
PDB IDs		6V0O 9E3A 9E3B
Enriched GO Terms of Interacting Partners?		Methylosome Spliceosomal SnRNP Assembly Histone Pre-mRNA DCP Binding U7 SnRNP U1 SnRNP Binding Protein-RNA Complex Assembly 7-methylguanosine Cap Hypermethylation Regulation Of Dopamine Receptor Signaling Pathway U4 SnRNP Structural Constituent Of Cytoskeleton Small Nuclear Ribonucleoprotein Complex Regulation Of Translational Initiation SMN-Sm Protein Complex Macromolecule Methylation U1 SnRNP U5 SnRNP Cytosol U2-type Prespliceosome Assembly U12-type Spliceosomal Complex Regulation Of Protein Localization To Cell Periphery Cortical Cytoskeleton Ribonucleoprotein Complex Cortical Actin Cytoskeleton Organization U2-type Spliceosomal Complex U2-type Catalytic Step 2 Spliceosome U2 SnRNP Methyl-CpG Binding Positive Regulation Of MRNA Splicing, Via Spliceosome Protein Methylation U4/U6 X U5 Tri-snRNP Complex Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Response To Environmental Enrichment Negative Regulation Of Translational Initiation Negative Regulation Of RNA-dependent RNA Polymerase Activity Cortical Cytoskeleton Organization Spliceosomal Complex Assembly U2-type Precatalytic Spliceosome Methylation Positive Regulation Of RNA Splicing Positive Regulation Of Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Oocyte Axis Specification Cytoplasmic U SnRNP Body RNA Binding Protein Metabolic Process MRNA Metabolic Process Regulation Of Norepinephrine Uptake Swimming Behavior Cytoskeletal Protein Binding U2 SnRNP Binding	Methylosome MRNA Cis Splicing, Via Spliceosome PICln-Sm Protein Complex Positive Regulation Of RNA Splicing Spliceosomal SnRNP Assembly Cell Volume Homeostasis Positive Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Cell Size Spliceosomal Complex Regulation Of RNA Splicing Inorganic Anion Transport Regulation Of MRNA Processing RNA Splicing, Via Transesterification Reactions Protein-RNA Complex Assembly Chloride Transport MRNA Splicing, Via Spliceosome Positive Regulation Of MRNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Monoatomic Anion Transport
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