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AGAP1 and GRB7
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
AGAP1
GRB7
Gene Name
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
growth factor receptor-bound protein 7
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytosol
Plasma Membrane
Focal Adhesion
Cytoplasmic Stress Granule
Cell Projection
Molecular Function
GTP Binding
Phospholipid Binding
ARF GTPase Activator Activity
Zinc Ion Binding
RNA Binding
SH3/SH2 Adaptor Activity
Protein Binding
Protein Kinase Binding
Phosphatidylinositol Binding
Identical Protein Binding
Biological Process
Small GTPase Mediated Signal Transduction
Protein Transport
Regulation Of ARF GTPase Activity
Positive Regulation Of GTPase Activity
Epidermal Growth Factor Receptor Signaling Pathway
Blood Coagulation
Positive Regulation Of Signal Transduction
Negative Regulation Of Translation
Positive Regulation Of Cell Migration
Stress Granule Assembly
Leukocyte Migration
Pathways
Signaling by PDGF
Signaling by SCF-KIT
Signaling by ERBB2
Downstream signal transduction
GRB7 events in ERBB2 signaling
Tie2 Signaling
Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS
Menarche (age at onset) (
23667675
)
Protein-Protein Interactions
6 interactors:
APP
GRB7
GUCY1A3
GUCY1B3
SMN1
TK1
39 interactors:
A1BG
AGAP1
ATP5B
CALM1
CAV1
CPNE6
DOCK7
DYNC1I1
EGFR
ERBB2
ERBB3
FGB
FLAD1
GNB2
GRB2
HADHB
INSR
KCTD6
KIT
KMT2B
LAX1
LY6G6F
MAP3K14
MSH2
PDGFRB
PDHB
PHAX
PKM
PTK2
RET
RND1
RPS2
SETDB1
SHC1
TEK
TLE1
TMSB4X
TRIM36
ZBTB16
Entrez ID
116987
2886
HPRD ID
16359
03311
Ensembl ID
ENSG00000157985
ENSG00000141738
Uniprot IDs
B2RZG9
Q9UPQ3
Q14451
PDB IDs
1MW4
1WGR
2L4K
2QMS
3PQZ
Enriched GO Terms of Interacting Partners
?
Blood Coagulation
Hemostasis
Regulation Of Body Fluid Levels
Wound Healing
Nitric Oxide Mediated Signal Transduction
CGMP Biosynthetic Process
Response To Wounding
CGMP Metabolic Process
Cyclic Purine Nucleotide Metabolic Process
Nucleotide Biosynthetic Process
Cyclic Nucleotide Biosynthetic Process
Cyclic Nucleotide Metabolic Process
Nucleotide Metabolic Process
Fetal Process Involved In Parturition
Nucleobase-containing Small Molecule Metabolic Process
Response To Defense-related Host Nitric Oxide Production
Skeletal Muscle Cell Proliferation
Synaptic Growth At Neuromuscular Junction
Second-messenger-mediated Signaling
Cellular Component Assembly
Collateral Sprouting In Absence Of Injury
Purine Nucleotide Biosynthetic Process
Ribose Phosphate Biosynthetic Process
Ribonucleoprotein Complex Assembly
Collateral Sprouting
Axon Midline Choice Point Recognition
Small Molecule Metabolic Process
Nucleobase-containing Compound Metabolic Process
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Response To Cortisol
Thymidine Metabolic Process
Organophosphate Metabolic Process
Response To Host Immune Response
Axon Choice Point Recognition
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Deoxyribonucleoside Monophosphate Biosynthetic Process
Regulation Of Translation
Relaxation Of Vascular Smooth Muscle
Cellular Nitrogen Compound Metabolic Process
Ribonucleotide Metabolic Process
Neuron Remodeling
Relaxation Of Smooth Muscle
Pyrimidine Nucleoside Salvage
Pyrimidine-containing Compound Salvage
Purine Nucleotide Metabolic Process
Blood Circulation
Ribose Phosphate Metabolic Process
Phosphate-containing Compound Metabolic Process
Ribonucleoprotein Complex Biogenesis
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Regulation Of Cell Adhesion
Peptidyl-tyrosine Phosphorylation
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Phosphorylation
Positive Regulation Of Catalytic Activity
Positive Regulation Of Transferase Activity
Regulation Of Phosphorylation
Positive Regulation Of Protein Phosphorylation
Intracellular Signal Transduction
Immune System Process
Regulation Of MAPK Cascade
Regulation Of Kinase Activity
Positive Regulation Of Kinase Activity
Fibroblast Growth Factor Receptor Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Intracellular Signal Transduction
Fc Receptor Signaling Pathway
Regulation Of Protein Phosphorylation
Positive Regulation Of Metabolic Process
Enzyme Linked Receptor Protein Signaling Pathway
Cellular Response To Fibroblast Growth Factor Stimulus
Positive Regulation Of Protein Modification Process
Regulation Of MAP Kinase Activity
Positive Regulation Of Cellular Protein Metabolic Process
Response To Fibroblast Growth Factor
Regulation Of Protein Kinase Activity
Neurotrophin TRK Receptor Signaling Pathway
Wound Healing
Immune Response-regulating Signaling Pathway
Neurotrophin Signaling Pathway
Positive Regulation Of Protein Kinase Activity
Positive Regulation Of Protein Metabolic Process
Fc-epsilon Receptor Signaling Pathway
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of Signal Transduction
Regulation Of Cellular Ketone Metabolic Process
Regulation Of Catalytic Activity
Regulation Of Immune System Process
Regulation Of Signal Transduction
Response To Wounding
Regulation Of Cellular Amino Acid Metabolic Process
Positive Regulation Of Protein Serine/threonine Kinase Activity
Peptidyl-amino Acid Modification
Signal Transduction By Phosphorylation
Positive Regulation Of Cellular Metabolic Process
Response To Hormone
Regulation Of Cellular Protein Metabolic Process
Tagcloud
?
adapter
appears
avidly
bear
bps
conversely
denote
domain
domains
dramatically
existence
grb10
grb14
homology
interact
interaction
interacts
ir
location
loop
obvious
paired
pleckstrin
resemblance
sh2
summary
unidentified
y1150f
y1151f
Tagcloud (Difference)
?
adapter
appears
avidly
bear
bps
conversely
denote
domain
domains
dramatically
existence
grb10
grb14
homology
interact
interaction
interacts
ir
location
loop
obvious
paired
pleckstrin
resemblance
sh2
summary
unidentified
y1150f
y1151f
Tagcloud (Intersection)
?