NR2F2 and TRIP4

Number of citations of the paper that reports this interaction (PubMedID 20211142)
41

Data Source:
BioGRID (two hybrid)

		NR2F2	TRIP4
Description		nuclear receptor subfamily 2 group F member 2	thyroid hormone receptor interactor 4
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Cytoskeleton Nuclear Body Neuromuscular Junction Protein-containing Complex RQC-trigger Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Retinoic Acid Binding DNA Binding DNA-binding Transcription Factor Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Protein Homodimerization Activity Sequence-specific DNA Binding Metal Ion Binding	Protease Binding Transcription Coactivator Activity Protein Binding Zinc Ion Binding Nuclear Receptor Binding Protein Kinase Binding Nuclear Estrogen Receptor Binding Histone Acetyltransferase Binding Ubiquitin-like Protein Ligase Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development Neuron Migration Maternal Placenta Development Negative Regulation Of Endothelial Cell Proliferation Lymph Vessel Development Positive Regulation Of Systemic Arterial Blood Pressure Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Nervous System Development Skeletal Muscle Tissue Development Female Gonad Development Fertilization Anterior/posterior Pattern Specification Radial Pattern Formation Negative Regulation Of Endothelial Cell Migration Cell Differentiation Intracellular Receptor Signaling Pathway Forebrain Development Response To Estradiol Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Blood Vessel Morphogenesis Placenta Blood Vessel Development Trophoblast Giant Cell Differentiation Lymphatic Endothelial Cell Fate Commitment Negative Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Interneuron Migration	Regulation Of DNA-templated Transcription Estrogen Receptor Signaling Pathway Ribosome Disassembly Regulation Of Myoblast Differentiation Positive Regulation Of DNA-templated Transcription Rescue Of Stalled Ribosome Ribosome-associated Ubiquitin-dependent Protein Catabolic Process
Pathways		Transcriptional regulation of white adipocyte differentiation	ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Birth weight ( 31043758) Cannabis use ( 27023175) Cerebrospinal fluid p-tau levels in Alzheimer's disease dementia ( 29274321) Chronotype ( 30696823) Cognitive decline rate in late mild cognitive impairment ( 26252872) Immune response to measles-mumps-rubella vaccine ( 24811271) Lymphangioleiomyomatosis (sporadic) ( 31000673) Metabolite levels ( 23823483) Motion sickness ( 25628336) Optic disc area ( 25631615) Optic disc size ( 31809533) Photic sneeze reflex ( 27182965) PR interval ( 32439900) Response to TNF-alpha inhibitors in rheumatoid arthritis ( 22569225) Serum alkaline phosphatase levels ( 33547301) Sex hormone-binding globulin levels ( 22829776) Very long-chain saturated fatty acid levels (fatty acid 22:0) ( 25378659)	Alzheimer's disease (late onset) ( 24162737) Neuroticism ( 29255261)
Interacting Genes		21 interacting genes: BCL11A BCL11B BIK EP300 FOXP1 FOXP2 FOXP4 HDAC1 HIPK3 MYOD1 NCOR2 NR2F6 NR3C1 NSD1 PHB2 PIAS1 SETD7 SQSTM1 TENT5A TRIM24 TRIP4	23 interacting genes: AR ASCC2 ASCC3 CREBBP EP300 ESR1 ESR2 GTF2A1 JUN NCOA1 NEK6 NFKB1 NR2F2 PAX9 PPARG RARA RELA RXRA SRF TBP THRB UBC XBP1
Entrez ID		7026	9325
HPRD ID		00139	05140
Ensembl ID		ENSG00000185551	ENSG00000103671
Uniprot IDs		F1D8R0 P24468	Q15650
PDB IDs		3CJW	2E5O 8ALZ 8YEW 8YEY 8YFI 8YFJ 8YXW 8YXX
Enriched GO Terms of Interacting Partners?		Negative Regulation Of RNA Metabolic Process Nuclear Receptor Binding Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription Chromatin Regulation Of RNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Primary Metabolic Process Negative Regulation Of Metabolic Process DNA Binding Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Androgen Receptor Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Sequence-specific DNA Binding Chromatin Binding Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Zinc Ion Binding Nucleus Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Nucleoplasm Regulation Of Metabolic Process Positive Regulation Of RNA Metabolic Process DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Negative Regulation Of Androgen Receptor Signaling Pathway Positive Regulation Of Macromolecule Metabolic Process Core Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity P53 Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nuclear Androgen Receptor Binding Positive Regulation Of Metabolic Process Regulation Of Apoptotic Process Chromatin Organization Macromolecule Biosynthetic Process Negative Regulation Of Protein Oligomerization Regulation Of Programmed Cell Death	Positive Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Nucleoplasm Transcription Coactivator Binding Nuclear Receptor Activity Positive Regulation Of RNA Metabolic Process Chromatin Positive Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Sequence-specific DNA Binding Negative Regulation Of DNA-templated Transcription Intracellular Receptor Signaling Pathway Negative Regulation Of RNA Biosynthetic Process Hormone-mediated Signaling Pathway Regulation Of MiRNA Metabolic Process Chromatin Binding DNA-binding Transcription Factor Activity Nucleobase-containing Compound Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Metabolic Process Nuclear Receptor-mediated Signaling Pathway DNA Binding Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Response To Hormone Regulation Of MiRNA Transcription Nucleic Acid Metabolic Process Regulation Of RNA Metabolic Process Transcription Regulator Complex Chromatin DNA Binding Transcription Cis-regulatory Region Binding MRNA Transcription By RNA Polymerase II Enzyme Binding Positive Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Response To Lipid Nucleus DNA-binding Transcription Factor Activity, RNA Polymerase II-specific MRNA Transcription Positive Regulation Of Metabolic Process RNA Metabolic Process Positive Regulation Of MiRNA Metabolic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?