TRMT61A and TMEM121

Data Source: HiPPIP (Novel)

		TRMT61A	TMEM121
Name		tRNA methyltransferase 61A	transmembrane protein 121
Structure			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm TRNA (m1A) Methyltransferase Complex	Membrane
	Molecular Function	Protein Binding Methyltransferase Activity Transferase Activity MRNA (adenine-N1-)-methyltransferase Activity TRNA (adenine(58)-N1)-methyltransferase Activity	Protein Binding
	Biological Process	RNA Processing MRNA Processing TRNA Processing TRNA Methylation Methylation	None
Pathways		tRNA modification in the nucleus and cytosol	None
GWAS		Autism spectrum disorder or schizophrenia ( 28540026 ) Body mass index ( 26426971 ) Brain morphology (MOSTest) ( 32665545 ) Branched-chain amino acid levels (Isoleucine) ( 27898682 ) Extremely high intelligence ( 29520040 ) Hemoglobin levels ( 32327693 ) Intelligence (MTAG) ( 29326435 ) Mean corpuscular volume ( 27863252 32888494 ) Red blood cell count ( 32888494 ) Schizophrenia ( 25056061 )	Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223 ) IgG N-glycosylation phenotypes (multivariate analysis) ( 32128391 )
Novel Interactors		8 novel interactors: ADSS1 AHNAK2 CLBA1 COA8 IGHV5-78 PLD4 TDRD9 TMEM121	1 novel interactors: TRMT61A
Interacting Genes		2 interacting genes: TCL1A TRMT6	14 interacting genes: ARL13B EHHADH GJA8 LMO3 MUC1 NCK2 POLR1C REEP4 SLC10A1 TMED8 TMEM14B TMEM31 TMX2 ZBTB24
Entrez ID		115708	80757
HPRD ID		08810	14652
Ensembl ID		ENSG00000166166	ENSG00000184986
Uniprot IDs		Q96FX7	Q9BTD3
PDB IDs		5CCB 5CCX 5CD1	Not available