TRMT61A and CLBA1

Data Source: HiPPIP (Novel)

		TRMT61A	CLBA1
Name		tRNA methyltransferase 61A	clathrin binding box of aftiphilin containing 1
Structure			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm TRNA (m1A) Methyltransferase Complex	AP-1 Adaptor Complex Trans-Golgi Network Membrane
	Molecular Function	Protein Binding Methyltransferase Activity Transferase Activity MRNA (adenine-N1-)-methyltransferase Activity TRNA (adenine(58)-N1)-methyltransferase Activity	Clathrin Binding
	Biological Process	RNA Processing MRNA Processing TRNA Processing TRNA Methylation Methylation	Intracellular Transport
Pathways		tRNA modification in the nucleus and cytosol	None
GWAS		Autism spectrum disorder or schizophrenia ( 28540026 ) Body mass index ( 26426971 ) Brain morphology (MOSTest) ( 32665545 ) Branched-chain amino acid levels (Isoleucine) ( 27898682 ) Extremely high intelligence ( 29520040 ) Hemoglobin levels ( 32327693 ) Intelligence (MTAG) ( 29326435 ) Mean corpuscular volume ( 27863252 32888494 ) Red blood cell count ( 32888494 ) Schizophrenia ( 25056061 )	No GWAS studies recorded
Novel Interactors		8 novel interactors: ADSS1 AHNAK2 CLBA1 COA8 IGHV5-78 PLD4 TDRD9 TMEM121	1 novel interactors: TRMT61A
Interacting Genes		2 interacting genes: TCL1A TRMT6	None recorded
Entrez ID		115708	122616
HPRD ID		08810	12656
Ensembl ID		ENSG00000166166	ENSG00000140104
Uniprot IDs		Q96FX7	Q96F83
PDB IDs		5CCB 5CCX 5CD1	Not available
GO Terms Enriched among Interactors		None	MRNA (adenine-N1-)-methyltransferase Activity TRNA (m1A) Methyltransferase Complex TRNA (adenine(58)-N1)-methyltransferase Activity TRNA Methylation TRNA Modification RNA Methylation Macromolecule Methylation TRNA Processing RNA Modification TRNA Metabolic Process Methyltransferase Activity Methylation