TRMT61A and TRMT6

Number of citations of the paper that reports this interaction (PMID 16043508)
10

Data Source:
HPRD (in vivo)

		TRMT61A	TRMT6
Gene Name		tRNA methyltransferase 61A	tRNA methyltransferase 6
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus TRNA (m1A) Methyltransferase Complex	Nucleus
	Molecular Function	TRNA (adenine-N1-)-methyltransferase Activity	Translation Initiation Factor Activity Poly(A) RNA Binding
	Biological Process	TRNA Methylation	Translational Initiation Regulation Of Translational Initiation TRNA Processing
Pathways
Drugs
Diseases
GWAS			Menarche and menopause (age at onset) ( 19448621)
Protein-Protein Interactions		1 interactors: TRMT6	3 interactors: FOXJ1 HHEX TRMT61A
Entrez ID		115708	51605
HPRD ID		08810	13027
Ensembl ID		ENSG00000166166	ENSG00000089195
Uniprot IDs		Q96FX7	B4DUV6 Q9UJA5
PDB IDs
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Lung Ciliated Cell Differentiation Central Tolerance Induction Hepatic Duct Development Glomerular Parietal Epithelial Cell Development Positive Regulation Of Central B Cell Tolerance Induction Hepatoblast Differentiation Positive Regulation Of B Cell Tolerance Induction Negative Regulation Of Germinal Center Formation Lung Development Respiratory Tube Development Gall Bladder Development Glomerular Parietal Epithelial Cell Differentiation Negative Regulation Of Transcription By Transcription Factor Localization Respiratory System Development Primary Lung Bud Formation Metanephric Part Of Ureteric Bud Development Negative Regulation Of Interleukin-6 Biosynthetic Process Common Bile Duct Development Negative Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Establishment Of Apical/basal Cell Polarity Tolerance Induction Negative Regulation Of Transcription By Competitive Promoter Binding Pattern Specification Process Establishment Of Monopolar Cell Polarity Negative Regulation Of T Cell Differentiation In Thymus Primitive Streak Formation Poly(A)+ MRNA Export From Nucleus Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Epithelial Cell Differentiation Regulation Of Germinal Center Formation Hepatocyte Differentiation Interkinetic Nuclear Migration RNA Metabolic Process Immune System Development Tube Development Forebrain Morphogenesis Regulation Of Interleukin-6 Biosynthetic Process Left/right Pattern Formation TRNA Methylation Brain Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Thyroid Gland Development Head Development Establishment Or Maintenance Of Apical/basal Cell Polarity Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Transcription From RNA Polymerase II Promoter Regulation Of T Cell Differentiation In Thymus Metanephros Morphogenesis Negative Regulation Of Protein Metabolic Process
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