GEMIN6 and GEMIN7

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid, pull down, affinity chromatography technology)
HPRD (in vivo, in vitro)

		GEMIN6	GEMIN7
Gene Name		gem (nuclear organelle) associated protein 6	gem (nuclear organelle) associated protein 7
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Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Nuclear Body SMN Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body SMN Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Gene Expression NcRNA Metabolic Process	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Gene Expression NcRNA Metabolic Process
Pathways		snRNP Assembly Metabolism of non-coding RNA	snRNP Assembly Metabolism of non-coding RNA
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: GEMIN7 RN7SL1 RNU1-1 RNU2-1 SNRPB SNRPD2 SNRPD3 SNRPE SNRPF SNRPG STRAP TOX4	20 interactors: ADD1 EDRF1 FEZ1 GEMIN6 GOLM1 KAT5 KIAA1377 RN7SL1 RNU1-1 RNU2-1 RPLP1 SHC1 SMN1 SNRPB SNRPD2 SNRPD3 SNRPE STRAP TAOK1 TUBA1A
Entrez ID		79833	79760
HPRD ID		06110	07600
Ensembl ID			ENSG00000142252
Uniprot IDs		Q8WXD5	Q9H840
PDB IDs		1Y96	1Y96
Enriched GO Terms of Interacting Partners?		Spliceosomal SnRNP Assembly Ribonucleoprotein Complex Assembly MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Ribonucleoprotein Complex Biogenesis RNA Splicing Histone MRNA Metabolic Process MRNA Processing MRNA Metabolic Process RNA Processing Termination Of RNA Polymerase II Transcription Cellular Macromolecular Complex Assembly DNA-templated Transcription, Termination NcRNA Metabolic Process MRNA 3'-end Processing RNA 3'-end Processing Cellular Component Assembly RNA Metabolic Process Spliceosomal Complex Assembly Gene Expression Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation Cellular Macromolecule Biosynthetic Process Maintenance Of Gastrointestinal Epithelium Cellular Metabolic Process Macromolecule Biosynthetic Process Negative Regulation Of Epithelial To Mesenchymal Transition Epithelial Structure Maintenance Negative Regulation Of Stem Cell Differentiation Negative Regulation Of Epithelial Cell Migration	Spliceosomal SnRNP Assembly Ribonucleoprotein Complex Assembly MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process Ribonucleoprotein Complex Biogenesis RNA Splicing Cellular Macromolecular Complex Assembly MRNA Processing RNA Processing Spliceosomal Complex Assembly Cellular Component Assembly Histone MRNA Metabolic Process NcRNA Metabolic Process RNA Metabolic Process Termination Of RNA Polymerase II Transcription Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process DNA-templated Transcription, Termination MRNA 3'-end Processing Nitrogen Compound Metabolic Process RNA 3'-end Processing Cellular Metabolic Process Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Positive Regulation Of Nuclease Activity RNA Biosynthetic Process Cellular Response To Organic Substance Execution Phase Of Apoptosis Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Positive Regulation Of Protein Modification Process Transcription, DNA-templated Response To Unfolded Protein Positive Regulation Of Protein Kinase Activity Positive Regulation Of Kinase Activity Regulation Of Protein Phosphorylation Response To Organic Substance Response To Endoplasmic Reticulum Stress Cellular Process Positive Regulation Of Transferase Activity Positive Regulation Of Cellular Protein Metabolic Process Cytoskeleton Organization Tissue Homeostasis Cellular Response To Growth Factor Stimulus Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation
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