VASN and RNF31

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		VASN	RNF31
Gene Name		vasorin	ring finger protein 31
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Mitochondrion Lysosomal Membrane Plasma Membrane Cell Surface Integral Component Of Membrane Extracellular Vesicular Exosome	Cytoplasm Cytoplasmic Side Of Plasma Membrane CD40 Receptor Complex LUBAC Complex
	Molecular Function	Transforming Growth Factor Beta Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Ubiquitin Protein Ligase Binding Ubiquitin Binding
	Biological Process	Negative Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Hypoxia Cellular Response To Redox State	Protein Polyubiquitination CD40 Signaling Pathway Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling T Cell Receptor Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Linear Polyubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: RNF31 TGFB1 TGFB2 TGFB3	27 interactors: AES ATN1 ATXN1 ATXN7 AZI2 CCDC24 GFI1B IKBKG KIF1A KRTAP9-2 NOS3 NR0B1 NR0B2 PITX1 PRKCA RBCK1 SMAD3 SNRPC SOCS3 TRAF1 TRIM25 TSSC4 UBC UBE2D1 UBE2D3 VASN VCP
Entrez ID		114990	55072
HPRD ID		10587	11516
Ensembl ID		ENSG00000168140	ENSG00000092098
Uniprot IDs		Q6EMK4	Q96EP0
PDB IDs			2CT7 4DBG 4JUY
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Macrophage Cytokine Production SMAD Protein Import Into Nucleus Positive Regulation Of Epithelial To Mesenchymal Transition Face Morphogenesis Uterine Wall Breakdown Head Morphogenesis Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Salivary Gland Morphogenesis Salivary Gland Development Response To Progesterone Face Development Positive Regulation Of Stem Cell Differentiation Regulation Of Pathway-restricted SMAD Protein Phosphorylation SMAD Protein Signal Transduction Regulation Of Epithelial To Mesenchymal Transition Exocrine System Development Body Morphogenesis Platelet Degranulation Ossification Involved In Bone Remodeling Regulation Of Cytokine Production Involved In Immune Response Frontal Suture Morphogenesis Positive Regulation Of Ossification Tissue Remodeling Protein Import Into Nucleus Nuclear Import Positive Regulation Of Cell Division Negative Regulation Of Immune Response Digestive Tract Development Transforming Growth Factor Beta Receptor Signaling Pathway Cell Growth Digestive System Development Protein Import Gland Morphogenesis Positive Regulation Of Cell Morphogenesis Involved In Differentiation Positive Regulation Of Intracellular Signal Transduction Cranial Suture Morphogenesis Protein Localization To Nucleus Pathway-restricted SMAD Protein Phosphorylation Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of SMAD Protein Import Into Nucleus Regulation Of Immune Response Response To Transforming Growth Factor Beta Platelet Activation Positive Regulation Of Protein Secretion Regulation Of Ossification Regulation Of SMAD Protein Import Into Nucleus Craniofacial Suture Morphogenesis Response To Laminar Fluid Shear Stress Negative Regulation Of Cytokine Production Cell-cell Junction Organization	Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Signal Transduction Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Signaling Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Signaling Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of RNA Metabolic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Signal Transduction Negative Regulation Of Nucleic Acid-templated Transcription Transcription, DNA-templated Negative Regulation Of RNA Biosynthetic Process DNA-templated Transcription, Initiation RNA Biosynthetic Process Gene Expression Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process RNA Metabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway Response To Abiotic Stimulus Regulation Of Apoptotic Process MyD88-independent Toll-like Receptor Signaling Pathway Cellular Response To Organic Substance Toll-like Receptor 3 Signaling Pathway Regulation Of Cell Death Protein Ubiquitination Signaling Toll-like Receptor 4 Signaling Pathway Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Response To Organic Substance Protein Modification By Small Protein Conjugation Cell Communication Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Immune System Process Apoptotic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels
Tagcloud ?		accordingly addressed analog c6 cmed cmef consisting decompression degenerative disk diskectomy duratomy excel foraminal foraminotomy herniation hospitalization microendoscopic microsoft minimally modern ndi neck office operative spine stay stenosis vasa	adjuvant antiestrogens arise aromatase associates atypical confirms cytosol decreases diagnostics e3 eralpha establishes estrogen facilitates initially insights ligase mono occupied promoters reduces stability stabilizes stabilizing therapeutics ubiquitin ubiquitination utmost
Tagcloud (Difference) ?		accordingly addressed analog c6 cmed cmef consisting decompression degenerative disk diskectomy duratomy excel foraminal foraminotomy herniation hospitalization microendoscopic microsoft minimally modern ndi neck office operative spine stay stenosis vasa	adjuvant antiestrogens arise aromatase associates atypical confirms cytosol decreases diagnostics e3 eralpha establishes estrogen facilitates initially insights ligase mono occupied promoters reduces stability stabilizes stabilizing therapeutics ubiquitin ubiquitination utmost
Tagcloud (Intersection) ?