PTPMT1 and RGS20

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PTPMT1	RGS20
Gene Name		protein tyrosine phosphatase, mitochondrial 1	regulator of G-protein signaling 20
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Integral Component Of Mitochondrial Inner Membrane	Nucleus Cytoplasm Plasma Membrane
	Molecular Function	Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Tyrosine/serine/threonine Phosphatase Activity Phosphatidylglycerophosphatase Activity	GTPase Activator Activity Protein Binding
	Biological Process	Protein Dephosphorylation Phospholipid Metabolic Process Phosphatidylglycerol Biosynthetic Process Cardiolipin Biosynthetic Process Peptidyl-tyrosine Dephosphorylation Small Molecule Metabolic Process Glycerophospholipid Biosynthetic Process Inositol Phosphate Dephosphorylation	Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Termination Of G-protein Coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity
Pathways		Metabolism of lipids and lipoproteins Synthesis of PG Phospholipid metabolism Glycerophospholipid biosynthesis	Signaling by GPCR GPCR downstream signaling G alpha (z) signalling events G alpha (i) signalling events
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: KRT31 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP2-4 KRTAP5-9 KRTAP9-2 MAPK6 MDFI MTUS2 NOTCH2NL RGS20 SIAH1 TAB1 TRIM27	33 interactors: ADRB2 AQP1 CATSPER1 CRCT1 CREB5 FASLG GLRX3 GNAI1 GNAI2 GNAI3 GNAO1 GNAZ HOXA1 HSPD1 INS KIF1A KLHL38 KRTAP4-2 KRTAP5-6 KRTAP5-9 LCE1B LCE2A LCE2D LCE3E LCE4A MAPKBP1 OSTM1 OTX1 PTGER3 PTPMT1 PVRL3 STMN2 TBC1D16
Entrez ID		114971	8601
HPRD ID		15151	06225
Ensembl ID			ENSG00000147509
Uniprot IDs		Q8WUK0	H9NIM5 O76081
PDB IDs
Enriched GO Terms of Interacting Partners?		MAPK Cascade Signal Transduction By Phosphorylation JNK Cascade Negative Regulation Of Interleukin-2 Secretion Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade	Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Keratinization Keratinocyte Differentiation Epidermis Development Developmental Process Epidermal Cell Differentiation Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Organ Development System Development Multicellular Organismal Development Anatomical Structure Development Skin Development Heat Generation G-protein Coupled Receptor Signaling Pathway Cell Differentiation Regulation Of Adenylate Cyclase Activity Regulation Of Cyclase Activity Tissue Development Regulation Of CAMP Biosynthetic Process Epithelium Development Regulation Of CAMP Metabolic Process Negative Regulation Of Adenylate Cyclase Activity Negative Regulation Of Lyase Activity Epithelial Cell Differentiation Temperature Homeostasis Membrane Fusion Regulation Of Body Fluid Levels Cell-cell Signaling Negative Regulation Of CAMP Biosynthetic Process Sensory Organ Development Wound Healing Bicarbonate Transport Negative Regulation Of CAMP Metabolic Process Eye Morphogenesis Cell Activation Negative Regulation Of Nucleotide Metabolic Process Acute-phase Response Regulation Of Catalytic Activity Response To Wounding Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development Abducens Nerve Formation B Cell Cytokine Production Maintenance Of Symbiont-containing Vacuole By Host Transepithelial Water Transport Optokinetic Behavior Isotype Switching To IgG Isotypes Anion Homeostasis
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