CHUK and NCOR2

  • Number of citations of the paper that reports this interaction (PMID 15494311)
  • 74
  • Data Source:
  • BioGRID (enzymatic study, enzymatic study)
  • HPRD (in vitro)

CHUK

NCOR2

Gene Name conserved helix-loop-helix ubiquitous kinase nuclear receptor corepressor 2
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs) ( 23648065)
  • Cognitive performance ( 19734545)
Protein-Protein Interactions 75 interactors: AKT1 AKT2 BCL10 BTRC CASP8 CDC37 CHEK1 COPS5 CREBBP CSF2RA CSNK2A1 CTNNB1 CUEDC2 CUL1 EIF2AK2 ERBB2IP ESR1 FKBP5 FOXO3 HIST2H3C HIST3H3 HSP90AA1 HSP90AB1 HTT IKBKAP IKBKB IKBKE IKBKG IRS1 MAP3K1 MAP3K11 MAP3K14 MAP3K4 MAP3K7 MAP3K8 NCOA3 NCOR1 NCOR2 NFKB1 NFKB2 NFKBIA NFKBIB NLRP4 NOTCH3 NR2C2 PAX8 PEBP1 PIAS1 PRKCB PRKCI PRKCQ PRKDC PTPN11 RELA RICTOR RIPK2 RPL27 SRC SRPK1 SRPK2 STAP2 TANK TGFBR1 TNFAIP3 TNFRSF1A TNIP2 TP53 TRAF2 TRAF3IP2 TRAF4 TRIM27 TRPC4AP UBE2E3 UBE2I UBE2N 84 interactors: AHR AKT1 AP2M1 AR ARNT ATXN1 ATXN1L BCL6 C1D CBFA2T2 CEBPB CEP63 CHUK CIR1 CNOT2 DDX20 E2F1 ESR1 ESR2 FOS FOXP1 HDAC1 HDAC10 HDAC3 HDAC4 HDAC5 HDAC7 HIST1H4A HNF4A INPP5K IRF5 JUN MYBL2 MYOD1 NCOA3 NCOA6 NCOR1 NFE2L2 NFKB1 NFKBIA NFKBIB NFKBIE NR1D1 NR1H2 NR1H4 NR1I2 NR2F1 NR2F2 NR3C1 NR4A1 PML POU2F1 PPARA PPARD PPARG RANBP9 RARA RARB RARG RBPJ RELA RUNX1 RUNX1T1 RXRA RXRG SAP30 SIN3A SKIL SNW1 SP1 SPEN SRF STAT5A STAT5B SUMO1 TBL1X THRA THRB TNIK TNIP2 UBE2I VDR YWHAE ZBTB16
Entrez ID 1147 9612
HPRD ID 02811 02910
Ensembl ID ENSG00000213341 ENSG00000196498
Uniprot IDs O15111 C9J0Q5 C9JE98 C9JFD3 Q9Y618
PDB IDs 3BRT 1KKQ 1R2B 1XC5 2GPV 2L5G 2LTP 2ODD 3R29 3R2A 4A69
Enriched GO Terms of Interacting Partners?
Tagcloud ?
accentuated  analog  analogs  antineoplastic  attributes  coincided  confined  correspond  cyclooxygenase  encountered  govern  implying  instance  krox  microtubule  modulates  oligoadenylate  oncology  originate  prompts  questions  simply  stabilization  taxane  taxol  taxotere  termed  traits  unidentified 
amico  atm  dissect  entered  erg  formalin  fusions  hiseq  illumina  map2k5  maximise  mek5  men1  nbpf10  needle  ngs  opening  pik3cb  qiagen  read  routinely  screen  sections  spop  technologies  templates  tmprrs2  unstained  yielded 
Tagcloud (Difference) ?
accentuated  analog  analogs  antineoplastic  attributes  coincided  confined  correspond  cyclooxygenase  encountered  govern  implying  instance  krox  microtubule  modulates  oligoadenylate  oncology  originate  prompts  questions  simply  stabilization  taxane  taxol  taxotere  termed  traits  unidentified 
amico  atm  dissect  entered  erg  formalin  fusions  hiseq  illumina  map2k5  maximise  mek5  men1  nbpf10  needle  ngs  opening  pik3cb  qiagen  read  routinely  screen  sections  spop  technologies  templates  tmprrs2  unstained  yielded 
Tagcloud (Intersection) ?