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EXOSC8 and FHOD1
Number of citations of the paper that reports this interaction (PMID
15231747
)
44
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
EXOSC8
FHOD1
Gene Name
exosome component 8
formin homology 2 domain containing 1
Image
Gene Ontology Annotations
Cellular Component
Exosome (RNase Complex)
Nucleus
Nucleolus
Cytoplasm
Cytosol
Stress Fiber
Nucleus
Cytoplasm
Membrane
Bleb
Molecular Function
Exoribonuclease Activity
Protein Binding
AU-rich Element Binding
Actin Binding
Protein Binding
Identical Protein Binding
Biological Process
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
RRNA Processing
Biological_process
Gene Expression
Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Stress Fiber Assembly
Pathways
Regulation of mRNA stability by proteins that bind AU-rich elements
KSRP destabilizes mRNA
mRNA decay by 3' to 5' exoribonuclease
ATF4 activates genes
Tristetraprolin (TTP) destabilizes mRNA
PERK regulates gene expression
Unfolded Protein Response (UPR)
Deadenylation-dependent mRNA decay
Butyrate Response Factor 1 (BRF1) destabilizes mRNA
Drugs
Diseases
GWAS
Protein-Protein Interactions
42 interactors:
AEN
ATF2
COL23A1
COX5A
CRMP1
CWC22
DIS3
DUSP23
EXOSC1
EXOSC10
EXOSC2
EXOSC3
EXOSC4
EXOSC5
EXOSC6
EXOSC7
EXOSC9
FAM90A1
FHOD1
FOXN3
FRG1
LSM1
LSM7
MKRN1
MORN4
MPP6
OTUD4
RASSF1
REL
RPP14
SKIV2L2
SNRPC
TCEA2
TFAP4
TXNDC17
TXNDC9
UBC
UPF2
USP6
XRN1
XRN2
ZFP36
20 interactors:
ACTA1
ACTG1
APC
BBS1
BBS2
BBS4
BBS7
CR2
EXOSC8
GRB2
LNPEP
NCOA6
PFN2
PPARG
PRKG1
RAC1
RANBP2
RNF5
YWHAZ
ZMYND8
Entrez ID
11340
29109
HPRD ID
09351
06049
Ensembl ID
ENSG00000120699
ENSG00000135723
Uniprot IDs
Q96B26
Q9Y613
PDB IDs
2NN6
3DAD
Enriched GO Terms of Interacting Partners
?
Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
RNA Catabolic Process
Nuclear-transcribed MRNA Catabolic Process
MRNA Catabolic Process
MRNA Metabolic Process
RRNA Metabolic Process
RRNA Processing
RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Ribosome Biogenesis
Aromatic Compound Catabolic Process
Nuclear MRNA Surveillance
Ribonucleoprotein Complex Biogenesis
RNA Metabolic Process
Cellular Macromolecule Catabolic Process
NcRNA Metabolic Process
RNA Surveillance
RNA Phosphodiester Bond Hydrolysis
RRNA Catabolic Process
Nucleobase-containing Compound Metabolic Process
Nucleic Acid Phosphodiester Bond Hydrolysis
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Maturation Of 5.8S RRNA
Gene Expression
Cellular Nitrogen Compound Metabolic Process
Catabolic Process
Nitrogen Compound Metabolic Process
Nuclear Polyadenylation-dependent RRNA Catabolic Process
CUT Catabolic Process
DNA Deamination
Histone MRNA Catabolic Process
RNA Processing
Cellular Metabolic Process
Histone MRNA Metabolic Process
MRNA Processing
Intracellular MRNA Localization
Metabolic Process
Nuclear Polyadenylation-dependent TRNA Catabolic Process
Polyadenylation-dependent SnoRNA 3'-end Processing
Nuclear Retention Of Pre-mRNA With Aberrant 3'-ends At The Site Of Transcription
U4 SnRNA 3'-end Processing
TRNA Catabolic Process
Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic, 3'-5'
DNA Modification
Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)
RNA Splicing
SnoRNA Metabolic Process
RNA Splicing, Via Transesterification Reactions
Nonmotile Primary Cilium Assembly
Cell Projection Organization
Retina Homeostasis
Cell Projection Morphogenesis
Cell Part Morphogenesis
Tissue Homeostasis
Positive Regulation Of Organelle Organization
Cellular Component Assembly
Cell Morphogenesis
Organelle Organization
Multicellular Organismal Homeostasis
Organelle Assembly
Cytoskeleton Organization
Cellular Response To Stimulus
Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway
Positive Regulation Of Protein Polymerization
Regulation Of Cell Projection Assembly
Photoreceptor Cell Maintenance
Cell Differentiation
Cell Projection Assembly
Fat Cell Differentiation
Melanosome Transport
Pigment Granule Transport
Membrane Organization
Establishment Of Melanosome Localization
Response To Stimulus
Positive Regulation Of Cellular Component Biogenesis
Nervous System Development
Regulation Of Organelle Organization
Melanosome Localization
Signal Transduction
Cell Development
Organ Development
Homeostatic Process
Regulation Of Cilium Beat Frequency Involved In Ciliary Motility
Cell Surface Receptor Signaling Pathway
Positive Regulation Of Protein Complex Assembly
Cilium Assembly
Visual Perception
Sensory Perception Of Light Stimulus
Anatomical Structure Formation Involved In Morphogenesis
Cell Activation
Signaling
Cilium Organization
Leptin-mediated Signaling Pathway
Cell Communication
Cellular Pigmentation
Platelet Activation
Anatomical Structure Development
Blood Coagulation
Tagcloud
?
actin
adhesions
adhesive
arrays
assembly
bilayers
clusters
coordinated
depends
find
force
formin
impairs
insights
integrin
integrins
matrix
maturation
pillar
polymerization
question
raises
recruited
rho
sensing
spreading
steps
substrates
upstream
Tagcloud (Difference)
?
actin
adhesions
adhesive
arrays
assembly
bilayers
clusters
coordinated
depends
find
force
formin
impairs
insights
integrin
integrins
matrix
maturation
pillar
polymerization
question
raises
recruited
rho
sensing
spreading
steps
substrates
upstream
Tagcloud (Intersection)
?