COPE and COPB2

Number of citations of the paper that reports this interaction (PMID 10921873)
47

Data Source:
BioGRID (two hybrid, affinity chromatography technology, biochemical)

		COPE	COPB2
Gene Name		coatomer protein complex, subunit epsilon	coatomer protein complex, subunit beta 2 (beta prime)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Golgi Apparatus Cytosol COPI Vesicle Coat	Cytosol COPI Vesicle Coat
	Molecular Function	Structural Molecule Activity	Structural Molecule Activity
	Biological Process	ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Intra-Golgi Vesicle-mediated Transport Protein Transport COPI Coating Of Golgi Vesicle Membrane Organization	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To ER Intra-Golgi Vesicle-mediated Transport COPI Coating Of Golgi Vesicle Membrane Organization
Pathways		COPI Mediated Transport Golgi to ER Retrograde Transport	COPI Mediated Transport Golgi to ER Retrograde Transport
Drugs
Diseases
GWAS			Kawasaki disease ( 22446961)
Protein-Protein Interactions		9 interactors: ARF1 COPA COPB1 COPB2 COPG1 COPG2 EFHC2 RCHY1 TMED10	10 interactors: ARCN1 COPA COPE NDRG1 NFKB1 PRKCE RGS2 RGS4 SACM1L TMED10
Entrez ID		11316	9276
HPRD ID		06089	06103
Ensembl ID		ENSG00000105669	ENSG00000184432
Uniprot IDs		O14579	P35606
PDB IDs
Enriched GO Terms of Interacting Partners?		COPI Coating Of Golgi Vesicle COPI-coated Vesicle Budding Retrograde Vesicle-mediated Transport, Golgi To ER Golgi Vesicle Budding Vesicle Targeting, To, From Or Within Golgi Localization Within Membrane Vesicle Targeting Membrane Budding Golgi Vesicle Transport Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Establishment Of Organelle Localization Organelle Localization Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Intracellular Transport Membrane Organization Intracellular Protein Transport Protein Localization Establishment Of Localization In Cell Intra-Golgi Vesicle-mediated Transport Cellular Localization Cellular Protein Localization Transport Organelle Organization Pancreatic Juice Secretion Establishment Of Golgi Localization Cargo Loading Into Vesicle Golgi Localization Long Term Synaptic Depression Cellular Copper Ion Homeostasis COPII Vesicle Coating Regulation Of Arp2/3 Complex-mediated Actin Nucleation Regulation Of Beta-amyloid Formation Dendritic Spine Organization COPII-coated Vesicle Budding Copper Ion Homeostasis Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Actin Nucleation Regulation Of Defense Response To Virus By Virus Regulation Of Receptor Internalization Viral Process Protein Autoubiquitination	COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Vesicle Targeting, To, From Or Within Golgi Retrograde Vesicle-mediated Transport, Golgi To ER Localization Within Membrane Vesicle Targeting Membrane Budding Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Golgi Vesicle Transport Establishment Of Organelle Localization Membrane Organization Organelle Localization Response To Alkaloid Vesicle-mediated Transport Intracellular Transport Termination Of G-protein Coupled Receptor Signaling Pathway Termination Of Signal Transduction MyD88-independent Toll-like Receptor Signaling Pathway Positive Regulation Of Cellular Glucuronidation Cerebellar Purkinje Cell Layer Maturation Negative Regulation Of Interleukin-12 Biosynthetic Process Toll-like Receptor 4 Signaling Pathway Negative Regulation Of MAP Kinase Activity Regulation Of Phospholipase Activity Establishment Of Localization In Cell Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels ER To Golgi Vesicle-mediated Transport TRAM-dependent Toll-like Receptor 4 Signaling Pathway Toll-like Receptor Signaling Pathway Cellular Response To Oxygen Levels Regulation Of Protein Metabolic Process Positive Regulation Of Protein Polymerization Negative Regulation Of Calcidiol 1-monooxygenase Activity Positive Regulation Of Hyaluronan Biosynthetic Process Cerebellum Maturation Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Negative Regulation Of Protein Serine/threonine Kinase Activity Activation Of Innate Immune Response Cellular Localization Regulation Of Carbohydrate Metabolic Process Regulation Of MAPK Cascade Cellular Response To Lipopolysaccharide Protein Transport Negative Regulation Of MAPK Cascade
Tagcloud ?		alcohol beginning behaviours binge connected coping distress drinking entering esteem gender genders graduating hazardous inactivity medical nation norwegian perceived postal predictors questionnaires religious school schools senior students surveys tension	addiction axonogenesis bnip4 camk1gammab candidates classes cns dao dendritogenesis deregulation differentially dopaminergic glutamatergic grb2 great grik indicative magi1b morphine mu neurotransmission opioid otpb patterning serotonergic sox19b whose wls zebrafish
Tagcloud (Difference) ?		alcohol beginning behaviours binge connected coping distress drinking entering esteem gender genders graduating hazardous inactivity medical nation norwegian perceived postal predictors questionnaires religious school schools senior students surveys tension	addiction axonogenesis bnip4 camk1gammab candidates classes cns dao dendritogenesis deregulation differentially dopaminergic glutamatergic grb2 great grik indicative magi1b morphine mu neurotransmission opioid otpb patterning serotonergic sox19b whose wls zebrafish
Tagcloud (Intersection) ?