COPE and TMED10

Number of citations of the paper that reports this interaction (PMID 9751720)
22

Data Source:
BioGRID (pull down)

		COPE	TMED10
Gene Name		coatomer protein complex, subunit epsilon	transmembrane emp24-like trafficking protein 10 (yeast)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Golgi Apparatus Cytosol COPI Vesicle Coat	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cis-Golgi Network Plasma Membrane Integral Component Of Membrane COPI-coated Vesicle Trans-Golgi Network Transport Vesicle Transport Vesicle Membrane Secretory Granule Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Melanosome Zymogen Granule Membrane Extracellular Vesicular Exosome Gamma-secretase Complex
	Molecular Function	Structural Molecule Activity	Protein Binding Syntaxin Binding Protein Complex Binding
	Biological Process	ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Intra-Golgi Vesicle-mediated Transport Protein Transport COPI Coating Of Golgi Vesicle Membrane Organization	Kidney Development Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Golgi Organization Cargo Loading Into Vesicle COPI-coated Vesicle Budding Response To Alkaloid Regulated Secretory Pathway Vesicle Targeting, To, From Or Within Golgi COPI Coating Of Golgi Vesicle COPII Vesicle Coating Protein Oligomerization Regulation Of Beta-amyloid Formation
Pathways		COPI Mediated Transport Golgi to ER Retrograde Transport
Drugs
Diseases
GWAS			Height ( 19343178)
Protein-Protein Interactions		9 interactors: ARF1 COPA COPB1 COPB2 COPG1 COPG2 EFHC2 RCHY1 TMED10	15 interactors: APH1A ARCN1 ARF1 COPA COPB1 COPB2 COPE COPG1 COPZ1 DHODH GORASP2 NCSTN PSENEN SEC23B TMED2
Entrez ID		11316	10972
HPRD ID		06089	12013
Ensembl ID		ENSG00000105669	ENSG00000170348
Uniprot IDs		O14579	B4DL12 P49755
PDB IDs
Enriched GO Terms of Interacting Partners?		COPI Coating Of Golgi Vesicle COPI-coated Vesicle Budding Retrograde Vesicle-mediated Transport, Golgi To ER Golgi Vesicle Budding Vesicle Targeting, To, From Or Within Golgi Localization Within Membrane Vesicle Targeting Membrane Budding Golgi Vesicle Transport Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Establishment Of Organelle Localization Organelle Localization Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Intracellular Transport Membrane Organization Intracellular Protein Transport Protein Localization Establishment Of Localization In Cell Intra-Golgi Vesicle-mediated Transport Cellular Localization Cellular Protein Localization Transport Organelle Organization Pancreatic Juice Secretion Establishment Of Golgi Localization Cargo Loading Into Vesicle Golgi Localization Long Term Synaptic Depression Cellular Copper Ion Homeostasis COPII Vesicle Coating Regulation Of Arp2/3 Complex-mediated Actin Nucleation Regulation Of Beta-amyloid Formation Dendritic Spine Organization COPII-coated Vesicle Budding Copper Ion Homeostasis Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Actin Nucleation Regulation Of Defense Response To Virus By Virus Regulation Of Receptor Internalization Viral Process Protein Autoubiquitination	COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Vesicle Targeting, To, From Or Within Golgi Localization Within Membrane Vesicle Targeting Retrograde Vesicle-mediated Transport, Golgi To ER Membrane Budding Golgi Vesicle Transport Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Establishment Of Organelle Localization Organelle Localization Membrane Organization Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Intracellular Transport Intracellular Protein Transport Protein Localization Intra-Golgi Vesicle-mediated Transport Establishment Of Localization In Cell Amyloid Precursor Protein Catabolic Process Membrane Protein Intracellular Domain Proteolysis Membrane Protein Ectodomain Proteolysis Amyloid Precursor Protein Metabolic Process Cellular Localization Notch Receptor Processing Cellular Protein Localization Membrane Protein Proteolysis Organelle Organization Transport Ephrin Receptor Signaling Pathway ER To Golgi Vesicle-mediated Transport Notch Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Protein Processing Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Cerebellar Purkinje Cell Layer Maturation Apoptotic Signaling Pathway Axon Guidance Cerebellum Maturation 'de Novo' UMP Biosynthetic Process Body Fluid Secretion Axonogenesis Establishment Of Golgi Localization
Tagcloud ?		alcohol beginning behaviours binge connected coping distress drinking entering esteem gender genders graduating hazardous inactivity medical nation norwegian perceived postal predictors questionnaires religious school schools senior students surveys tension	aiming aip alignment boar brms1 chordc1 clues cops6 csde1 csfv ddx5 domestic fever gnb2l1 hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmem70 y2h
Tagcloud (Difference) ?		alcohol beginning behaviours binge connected coping distress drinking entering esteem gender genders graduating hazardous inactivity medical nation norwegian perceived postal predictors questionnaires religious school schools senior students surveys tension	aiming aip alignment boar brms1 chordc1 clues cops6 csde1 csfv ddx5 domestic fever gnb2l1 hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmem70 y2h
Tagcloud (Intersection) ?