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CDCA5 and XRCC6
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
CDCA5
XRCC6
Gene Name
cell division cycle associated 5
X-ray repair complementing defective repair in Chinese hamster cells 6
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Chromosome, Centromeric Region
Nuclear Chromatin
Nucleus
Nucleoplasm
Chromosome
Cytoplasm
Cytosol
Plasma Membrane
Cohesin Complex
Nuclear Telomere Cap Complex
Nucleus
Nucleoplasm
Transcription Factor Complex
Nucleolus
Cytosol
Membrane
Ku70:Ku80 Complex
Nonhomologous End Joining Complex
Molecular Function
Chromatin Binding
Protein Binding
DNA Binding
Damaged DNA Binding
Double-stranded DNA Binding
Double-stranded Telomeric DNA Binding
ATP-dependent DNA Helicase Activity
Protein Binding
ATP Binding
Protein C-terminus Binding
Transcription Regulatory Region DNA Binding
Poly(A) RNA Binding
5'-deoxyribose-5-phosphate Lyase Activity
Biological Process
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Double-strand Break Repair
Mitotic Sister Chromatid Cohesion
Mitotic Nuclear Division
Mitotic Chromosome Condensation
Mitotic Metaphase Plate Congression
Cell Division
Regulation Of Cohesin Localization To Chromatin
Telomere Maintenance
DNA Ligation
DNA Repair
Double-strand Break Repair
Double-strand Break Repair Via Nonhomologous End Joining
Transcription, DNA-templated
Brain Development
Viral Process
Positive Regulation Of Type I Interferon Production
DNA Duplex Unwinding
V(D)J Recombination
Innate Immune Response
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Neurogenesis
Cellular Hyperosmotic Salinity Response
Cellular Response To X-ray
Establishment Of Integrated Proviral Latency
Pathways
Establishment of Sister Chromatid Cohesion
Mitotic Prometaphase
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Mitotic Anaphase
S Phase
Mitotic Metaphase and Anaphase
M Phase
Cell Cycle, Mitotic
Cytosolic sensors of pathogen-associated DNA
HIV Infection
Processing of DNA ends prior to end rejoining
Integration of provirus
Early Phase of HIV Life Cycle
HIV Life Cycle
Nonhomologous End-joining (NHEJ)
STING mediated induction of host immune responses
Double-Strand Break Repair
IRF3-mediated induction of type I IFN
2-LTR circle formation
Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
7 interactors:
CDK1
IRAK3
KDM1A
RPAIN
SENP2
TTLL3
XRCC6
126 interactors:
ABCD4
ABL1
ACD
ADCY7
ANXA1
APEX1
AR
ARAP1
ATP6V1E1
BARD1
BAZ1A
BTG1
CAPN11
CBX5
CCNA1
CCT3
CD40
CDCA5
CDK2
CDKN1A
CEBPA
CENPU
CHAF1A
CHEK1
CLTC
CLU
CMTM6
COIL
COPB1
CREBBP
CSNK2A1
CTBP2
DLX2
DNTT
EFNA1
EGFR
EID1
ELF3
EP300
EPS8
FMNL1
GAL3ST4
GSE1
GZMA
GZMB
H2AFX
HERPUD1
HMGA2
HN1L
HOXB7
HOXC4
HOXD4
HSF1
HTT
ILVBL
KAT2A
KAT2B
KIAA0408
LIG3
MAP2K5
MAP4K2
MAPK8
MRE11A
MSX2
NAA15
NCF4
NCL
NCOA6
NHP2L1
NIT1
NOTCH1
PAEP
PAFAH1B3
PARP1
PCNA
PDK1
PDPK1
PDX1
PECAM1
PGAM1
PGR
PIN1
PLGRKT
PNRC2
POR
POU2F1
POU2F2
PRKDC
PRPF40A
PTTG1
QRSL1
RASA1
RBBP4
RGS2
RNF146
RPLP1
RPS10
RRAS2
RUNX2
SDHC
SEP15
SERPINA2
SERPINB9
SGOL1
SIRT3
SKIL
SMAD3
SMAD7
SNTA1
SPARC
TAC1
TADA3
TBCD
TCF4
TERF2
TERF2IP
TERT
TP53
VAV1
VBP1
WBP4
WRN
XRCC5
XRCC6BP1
YWHAZ
ZNF512B
Entrez ID
113130
2547
HPRD ID
13016
01071
Ensembl ID
ENSG00000146670
ENSG00000196419
Uniprot IDs
Q96FF9
B1AHC8
B1AHC9
P12956
PDB IDs
1JEQ
1JEY
1JJR
3RZX
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Negative Regulation Of Signal Transduction By P53 Class Mediator
Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Regulation Of Signal Transduction By P53 Class Mediator
Negative Regulation Of Protein Binding
Negative Regulation Of Intracellular Signal Transduction
MyD88-dependent Toll-like Receptor Signaling Pathway
Positive Regulation Of Macrophage Tolerance Induction
Regulation Of Primitive Erythrocyte Differentiation
Pronuclear Fusion
Negative Regulation Of Binding
Toll-like Receptor Signaling Pathway
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Embryonic Development
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
DNA Repair
Positive Regulation Of Gene Expression
Protein Polyglycylation
Regulation Of DNA Replication
Regulation Of Response To DNA Damage Stimulus
Positive Regulation Of Cellular Biosynthetic Process
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Cellular Protein Modification Process
Activation Of Innate Immune Response
Regulation Of Protein Binding
Cellular Hyperosmotic Salinity Response
Regulation Of Intracellular Signal Transduction
Regulation Of Transcription From RNA Polymerase II Promoter
Muscle Cell Development
Negative Regulation Of Macrophage Cytokine Production
Positive Regulation Of Innate Immune Response
Regulation Of Cellular Protein Metabolic Process
Protein Desumoylation
Cellular Response To DNA Damage Stimulus
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Cellular Response To X-ray
Positive Regulation Of Immune System Process
Immune System Process
Negative Regulation Of Chromatin Binding
Regulation Of Schwann Cell Differentiation
DNA Recombination
Regulation Of Protein Metabolic Process
Histone H3-K9 Demethylation
Negative Regulation Of Histone H3-K4 Methylation
Histone H3-K4 Demethylation
Establishment Of Integrated Proviral Latency
Regulation Of Innate Immune Response
Regulation Of Binding
Chromosome Organization
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Regulation Of Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Cell Cycle
Heterocycle Metabolic Process
Nucleobase-containing Compound Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Regulation Of RNA Metabolic Process
RNA Biosynthetic Process
Macromolecule Biosynthetic Process
Response To Stress
Regulation Of Gene Expression
Positive Regulation Of Cellular Biosynthetic Process
RNA Metabolic Process
Regulation Of Transcription, DNA-templated
Chromosome Organization
Regulation Of Cell Death
Regulation Of Cellular Component Organization
Regulation Of Nucleic Acid-templated Transcription
Regulation Of Apoptotic Process
Cell Cycle Process
Regulation Of RNA Biosynthetic Process
Transcription, DNA-templated
Response To Organic Substance
Cellular Response To Stress
Organelle Organization
Positive Regulation Of Gene Expression
Gene Expression
DNA Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Regulation Of Cell Cycle
Telomere Maintenance
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Cellular Process
Mitotic Cell Cycle
Embryo Development
Negative Regulation Of Cell Death
Negative Regulation Of Biosynthetic Process
Cellular Response To DNA Damage Stimulus
Biosynthetic Process
Regulation Of Catalytic Activity
Cellular Metabolic Process
Cellular Response To Organic Substance
Tagcloud
?
brca2
cellularity
cg
chance
copyright
cytopenia
genesis
genotype
genotyped
gg
heterozygote
hypercellular
john
karyotype
lig4
ltd
normocellular
polymorphism
polymorphisms
rad51
rs1801320
rs1805388
rs2267437
rs3835
rs4793191
rs9567623
sons
wiley
xrcc5
Tagcloud (Difference)
?
brca2
cellularity
cg
chance
copyright
cytopenia
genesis
genotype
genotyped
gg
heterozygote
hypercellular
john
karyotype
lig4
ltd
normocellular
polymorphism
polymorphisms
rad51
rs1801320
rs1805388
rs2267437
rs3835
rs4793191
rs9567623
sons
wiley
xrcc5
Tagcloud (Intersection)
?