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CDCA5 and SENP2
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
CDCA5
SENP2
Gene Name
cell division cycle associated 5
SUMO1/sentrin/SMT3 specific peptidase 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Chromosome, Centromeric Region
Nuclear Chromatin
Nucleus
Nucleoplasm
Chromosome
Cytoplasm
Cytosol
Plasma Membrane
Cohesin Complex
Nuclear Pore
Nucleoplasm
PML Body
Cytoplasmic Vesicle
Nuclear Membrane
Molecular Function
Chromatin Binding
Protein Binding
Protein Binding
SUMO-specific Protease Activity
Protein Domain Specific Binding
Biological Process
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Double-strand Break Repair
Mitotic Sister Chromatid Cohesion
Mitotic Nuclear Division
Mitotic Chromosome Condensation
Mitotic Metaphase Plate Congression
Cell Division
Regulation Of Cohesin Localization To Chromatin
Positive Regulation Of Protein Phosphorylation
Proteolysis
Heart Development
Dorsal/ventral Axis Specification
Protein Transport
Wnt Signaling Pathway
Protein Sumoylation
Protein Desumoylation
Regulation Of Wnt Signaling Pathway
Negative Regulation Of Protein Binding
Regulation Of DNA Endoreduplication
Negative Regulation Of Chromatin Binding
Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Post-translational Protein Modification
Cellular Protein Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
MRNA Transport
Trophoblast Giant Cell Differentiation
Labyrinthine Layer Development
Spongiotrophoblast Layer Development
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Establishment of Sister Chromatid Cohesion
Mitotic Prometaphase
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Mitotic Anaphase
S Phase
Mitotic Metaphase and Anaphase
M Phase
Cell Cycle, Mitotic
SUMO is proteolytically processed
Post-translational protein modification
SUMOylation
Processing and activation of SUMO
Drugs
Diseases
GWAS
Protein-Protein Interactions
7 interactors:
CDK1
IRAK3
KDM1A
RPAIN
SENP2
TTLL3
XRCC6
21 interactors:
AGTRAP
APP
ARL6IP1
AXIN1
CCDC155
CDCA5
CDK5RAP2
DAXX
FUNDC1
IKBKG
NEDD4L
NUP153
PML
RANGAP1
SUMO1
SUMO2
SUMO3
SYNE4
TMEM239
TPD52
TRIM63
Entrez ID
113130
59343
HPRD ID
13016
07002
Ensembl ID
ENSG00000146670
Uniprot IDs
Q96FF9
Q9HC62
PDB IDs
1TGZ
1TH0
2IO0
2IO1
2IO2
2IO3
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Negative Regulation Of Signal Transduction By P53 Class Mediator
Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Regulation Of Signal Transduction By P53 Class Mediator
Negative Regulation Of Protein Binding
Negative Regulation Of Intracellular Signal Transduction
MyD88-dependent Toll-like Receptor Signaling Pathway
Positive Regulation Of Macrophage Tolerance Induction
Regulation Of Primitive Erythrocyte Differentiation
Pronuclear Fusion
Negative Regulation Of Binding
Toll-like Receptor Signaling Pathway
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Embryonic Development
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
DNA Repair
Positive Regulation Of Gene Expression
Protein Polyglycylation
Regulation Of DNA Replication
Regulation Of Response To DNA Damage Stimulus
Positive Regulation Of Cellular Biosynthetic Process
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Cellular Protein Modification Process
Activation Of Innate Immune Response
Regulation Of Protein Binding
Cellular Hyperosmotic Salinity Response
Regulation Of Intracellular Signal Transduction
Regulation Of Transcription From RNA Polymerase II Promoter
Muscle Cell Development
Negative Regulation Of Macrophage Cytokine Production
Positive Regulation Of Innate Immune Response
Regulation Of Cellular Protein Metabolic Process
Protein Desumoylation
Cellular Response To DNA Damage Stimulus
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Cellular Response To X-ray
Positive Regulation Of Immune System Process
Immune System Process
Negative Regulation Of Chromatin Binding
Regulation Of Schwann Cell Differentiation
DNA Recombination
Regulation Of Protein Metabolic Process
Histone H3-K9 Demethylation
Negative Regulation Of Histone H3-K4 Methylation
Histone H3-K4 Demethylation
Establishment Of Integrated Proviral Latency
Regulation Of Innate Immune Response
Regulation Of Binding
Chromosome Organization
Positive Regulation Of Proteolysis
Positive Regulation Of Protein Metabolic Process
Regulation Of Protein Catabolic Process
Cellular Localization
Positive Regulation Of Protein Catabolic Process
Protein Sumoylation
Positive Regulation Of Cellular Protein Metabolic Process
PML Body Organization
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Positive Regulation Of Cellular Protein Catabolic Process
Protein Modification By Small Protein Conjugation
Regulation Of Proteolysis
Establishment Of Localization In Cell
Intracellular Receptor Signaling Pathway
Regulation Of Protein Ubiquitination
Positive Regulation Of Metabolic Process
Mitotic Cell Cycle
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Response To Stress
Regulation Of Protein Metabolic Process
Positive Regulation Of Proteasomal Protein Catabolic Process
JNK Cascade
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Cell Cycle
Viral Process
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Stress-activated MAPK Cascade
Establishment Of Organelle Localization
Stress-activated Protein Kinase Signaling Cascade
Nucleus Organization
Cell Cycle Process
Regulation Of Cellular Localization
Cellular Response To Stress
Mitotic Cell Cycle Process
Response To Abiotic Stimulus
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Activation Of MAPK Activity
Organelle Localization
Protein Localization To Nucleus
Regulation Of Protein Localization
Endoplasmic Reticulum Calcium Ion Homeostasis
Regulation Of Intracellular Transport
Cell Surface Receptor Signaling Pathway
Organelle Organization
Activation Of JUN Kinase Activity
Cellular Response To Stimulus
Cellular Response To DNA Damage Stimulus
Establishment Of Chromosome Localization
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Tagcloud
?
adequate
aerobic
atp
consistently
displaying
exhibit
glucose
glycolysis
glycolytic
hif1alpha
knockout
lactate
ly294002
mcf7
mef
mefs
metabolism
protease
proteases
represses
rescued
respiration
reveals
senps
shifts
subcellular
sumo
sumoylate
supply
Tagcloud (Difference)
?
adequate
aerobic
atp
consistently
displaying
exhibit
glucose
glycolysis
glycolytic
hif1alpha
knockout
lactate
ly294002
mcf7
mef
mefs
metabolism
protease
proteases
represses
rescued
respiration
reveals
senps
shifts
subcellular
sumo
sumoylate
supply
Tagcloud (Intersection)
?