PRAF2 and EBAG9

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PRAF2	EBAG9
Description		PRA1 domain family member 2	estrogen receptor binding site associated antigen 9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Endosome Membrane Membrane Presynapse Postsynapse Glutamatergic Synapse GABA-ergic Synapse	Golgi Membrane Golgi Apparatus Membrane Secretory Granule
	Molecular Function	Protein Binding	Protein Binding Peptidase Activator Activity Involved In Apoptotic Process
	Biological Process	Protein Transport L-glutamate Transmembrane Transport	Regulation Of Cell Growth T Cell Mediated Cytotoxicity Apoptotic Process Adaptive Immune Memory Response Involving T Cells And B Cells
Pathways			Estrogen-dependent gene expression
Drugs
Diseases
GWAS			Metabolite levels ( 23823483) Nicotine dependence and major depression (severity of comorbidity) ( 30287806)
Interacting Genes		27 interacting genes: ABHD16A ADGRD1 AGR3 AQP6 ARL6IP5 CCR5 CD79A CFTR CIAO2A CLEC10A EBAG9 GJA5 GJA8 GPR152 HIBADH HSD17B11 MCEMP1 MIEF1 NDRG4 REEP4 RETREG3 RNF5 SLC10A6 TLCD4 TMEM14B TMX2 ZDHHC15	30 interacting genes: ACSL5 APOL2 BNIP3 C14orf180 CFHR5 CIAO2A CLEC4G CLN6 GOLPH3 GOLPH3L MGLL NEDD4 OR10AG1 ORMDL1 PEX16 PRAF2 REEP6 SLC30A2 SLC35A1 SLC35A4 SLC35B4 SNAPIN STX1A STX2 STX3 TMEM107 TPRG1 TRAF3IP3 VAPA VAPB
Entrez ID		11230	9166
HPRD ID		06596	05775
Ensembl ID		ENSG00000243279	ENSG00000147654
Uniprot IDs		O60831	O00559
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Nitrate Transmembrane Transporter Activity Protein Binding Fluid Transport Transmembrane Transport Water Transport Endoplasmic Reticulum Membrane Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Gap Junction Channel Activity Involved In Purkinje Myocyte-ventricular Cardiac Muscle Cell Electrical Coupling Mitral Valve Development Septum Primum Development Gap Junction Channel Activity Involved In Atrial Cardiac Muscle Cell-AV Node Cell Electrical Coupling Gap Junction Atrial Ventricular Junction Remodeling Gap Junction Channel Activity Involved In Bundle Of His Cell-Purkinje Myocyte Electrical Coupling Embryonic Heart Tube Development Gap Junction Channel Activity Positive Regulation Of Cell Communication By Chemical Coupling Atrial Cardiac Muscle Cell To AV Node Cell Communication By Electrical Coupling Vasomotion Purkinje Myocyte To Ventricular Cardiac Muscle Cell Communication By Electrical Coupling Regulation Of Purkinje Myocyte Action Potential Connexin Complex 3-hydroxyisobutyrate Dehydrogenase Activity Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport Positive Regulation Of Neuron Projection Development	Membrane Membrane Docking Vesicle Organization Organelle Localization By Membrane Tethering Vesicle Budding From Membrane Pyrimidine Nucleotide-sugar Transmembrane Transport Endoplasmic Reticulum Membrane Nucleotide-sugar Transmembrane Transport Membrane Organization SNARE Binding Membrane Fusion FFAT Motif Binding Protein Targeting To Golgi Apparatus Golgi Membrane Golgi Vesicle Budding Cargo Adaptor Activity Cellular Localization Vesicle Fusion COPII-coated Vesicle Budding Endoplasmic Reticulum-plasma Membrane Tethering Pyrimidine Nucleotide-sugar Transmembrane Transporter Activity Organelle Membrane Fusion SNAP Receptor Activity Endoplasmic Reticulum Localization Protein Transport SNARE Complex Organelle Fusion Organophosphate Ester Transport Golgi Cisterna Organelle Localization Intracellular Protein Localization Vesicle-mediated Transport Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Intracellular Transport Host-mediated Activation Of Viral Genome Replication Organelle Organization Vesicle Fusion To Plasma Membrane Endoplasmic Reticulum Organization Host-mediated Perturbation Of Viral Genome Replication Sphingomyelin Biosynthetic Process Vesicle Docking Establishment Of Localization In Cell Host-mediated Suppression Of Viral Genome Replication Establishment Of Protein Localization Intracellular Chemical Homeostasis Intracellular Protein Transport Synaptic Vesicle Membrane Organization Carbohydrate Derivative Transport Zymogen Granule Membrane Exocytosis
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