PRAF2 and MIEF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PRAF2	MIEF1
Description		PRA1 domain family member 2	mitochondrial elongation factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Endosome Membrane Membrane Presynapse Postsynapse Glutamatergic Synapse GABA-ergic Synapse	Mitochondrion Mitochondrial Outer Membrane Peroxisome Membrane
	Molecular Function	Protein Binding	Nucleotide Binding Protein Binding GDP Binding Identical Protein Binding ADP Binding
	Biological Process	Protein Transport L-glutamate Transmembrane Transport	Mitochondrial Fission Mitochondrion Organization Mitochondrial Fusion Positive Regulation Of Mitochondrial Fusion Positive Regulation Of Mitochondrial Fission Positive Regulation Of Protein Targeting To Membrane
Pathways			Mitochondrial ribosome-associated quality control
Drugs
Diseases
GWAS			Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean corpuscular hemoglobin ( 32888494)
Interacting Genes		27 interacting genes: ABHD16A ADGRD1 AGR3 AQP6 ARL6IP5 CCR5 CD79A CFTR CIAO2A CLEC10A EBAG9 GJA5 GJA8 GPR152 HIBADH HSD17B11 MCEMP1 MIEF1 NDRG4 REEP4 RETREG3 RNF5 SLC10A6 TLCD4 TMEM14B TMX2 ZDHHC15	22 interacting genes: ABHD5 AGTRAP ARFIP2 ATP5PF CMTM5 CMTM6 DNM1L FAM25A FAM25C FAM25G HTATIP2 MAGEA1 MED21 PLIN3 PRAF2 PRR4 PSMA1 SYP TNFRSF10D UBQLN1 UBQLN2 YWHAG
Entrez ID		11230	54471
HPRD ID		06596	13371
Ensembl ID		ENSG00000243279	ENSG00000100335
Uniprot IDs		O60831	B0QY95 Q9NQG6
PDB IDs			4NXT 4NXU 4NXV 4NXW 4NXX 5X9B 5X9C
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Nitrate Transmembrane Transporter Activity Protein Binding Fluid Transport Transmembrane Transport Water Transport Endoplasmic Reticulum Membrane Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Gap Junction Channel Activity Involved In Purkinje Myocyte-ventricular Cardiac Muscle Cell Electrical Coupling Mitral Valve Development Septum Primum Development Gap Junction Channel Activity Involved In Atrial Cardiac Muscle Cell-AV Node Cell Electrical Coupling Gap Junction Atrial Ventricular Junction Remodeling Gap Junction Channel Activity Involved In Bundle Of His Cell-Purkinje Myocyte Electrical Coupling Embryonic Heart Tube Development Gap Junction Channel Activity Positive Regulation Of Cell Communication By Chemical Coupling Atrial Cardiac Muscle Cell To AV Node Cell Communication By Electrical Coupling Vasomotion Purkinje Myocyte To Ventricular Cardiac Muscle Cell Communication By Electrical Coupling Regulation Of Purkinje Myocyte Action Potential Connexin Complex 3-hydroxyisobutyrate Dehydrogenase Activity Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport Positive Regulation Of Neuron Projection Development
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