MAFB and BACH1

Number of citations of the paper that reports this interaction (PMID 23661758)
2

Data Source:
BioGRID (fluorescent resonance energy transfer)

		MAFB	BACH1
Gene Name		v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B	BTB and CNC homology 1, basic leucine zipper transcription factor 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Factor Binding Sequence-specific DNA Binding	RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Heme Binding
	Biological Process	Transcription, DNA-templated Segment Specification Sensory Organ Development Respiratory Gaseous Exchange Rhombomere 5 Development Rhombomere 6 Development T Cell Differentiation In Thymus Brain Segmentation Inner Ear Morphogenesis Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Thymus Development	Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Regulation Of Transcription Involved In G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Pathways
Drugs
Diseases
GWAS		Cholesterol, total ( 20686565) Dupuytren's disease ( 21732829) LDL cholesterol ( 19060906 20686565) Obesity-related traits ( 23251661) Response to TNF antagonist treatment ( 18615156)	Pancreatic cancer ( 22158540) Visceral fat ( 22589738)
Protein-Protein Interactions		11 interactors: ATF4 BACH1 DDB1 FOS FOSL1 HOXD12 JUN MAF ZDHHC2 ZFP64 ZWINT	11 interactors: ANAPC5 ATF2 DDIT3 HMMR MAFB MAFF MAFG MAFK PATZ1 RBCK1 TP53
Entrez ID		9935	571
HPRD ID		07129	04127
Ensembl ID		ENSG00000204103	ENSG00000156273
Uniprot IDs		Q9Y5Q3	O14867 Q6ICU0
PDB IDs			2IHC
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Cellular Macromolecule Biosynthetic Process Cellular Response To Extracellular Stimulus Regulation Of DNA-templated Transcription In Response To Stress Macromolecule Biosynthetic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Response To Gravity Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Gene Expression Response To CAMP Positive Regulation Of Gene Expression Response To Oxidative Stress Cellular Nitrogen Compound Metabolic Process Learning Response To Organophosphorus Response To Extracellular Stimulus Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Purine-containing Compound Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Response To Abiotic Stimulus Response To Reactive Oxygen Species Response To Corticosterone Interaction With Symbiont Regulation Of Transcription, DNA-templated Response To Mechanical Stimulus Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Response To Mineralocorticoid Regulation Of RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Learning Or Memory Cellular Response To Calcium Ion Response To Progesterone Positive Regulation Of Myeloid Leukocyte Differentiation Toll-like Receptor 5 Signaling Pathway Cognition Toll-like Receptor 10 Signaling Pathway Regulation Of Gene Expression SMAD Protein Signal Transduction Regulation Of Nitrogen Compound Metabolic Process Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process	Transcription, DNA-templated RNA Biosynthetic Process ER Overload Response Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Gene Expression Regulation Of Gene Expression Positive Regulation Of Mitochondrial Membrane Permeability Regulation Of Nitrogen Compound Metabolic Process Blood Coagulation Cellular Macromolecule Biosynthetic Process Hemostasis Macromolecule Biosynthetic Process Negative Regulation Of Cell Cycle Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process T Cell Differentiation Mitotic Cell Cycle Checkpoint Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Mitochondrial Membrane Permeability Regulation Of Body Fluid Levels Regulation Of Membrane Permeability Wound Healing Negative Regulation Of Mitotic Cell Cycle Cell Cycle Checkpoint Lymphocyte Differentiation Regulation Of Epidermal Cell Differentiation Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Response To Wounding Multicellular Organismal Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process T Cell Aggregation T Cell Activation Lymphocyte Aggregation Biosynthetic Process Leukocyte Aggregation Anatomical Structure Development Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Mitochondrial Membrane Organization Leukocyte Cell-cell Adhesion Positive Regulation Of Gene Expression
Tagcloud ?		aminobutyric bioassay catalase cip1 cyp7a1 den deoxyguanosine diethylnitrosamine doses drinking exhibits f344 foci gaba gst hepatocarcinogenesis hydroxy modulating nrf2 placental powerful ppm sitchensis suppress suppressing transferase valerian valeriana waf1	architectural architecture bach2 bear btb bzip constitutes erythroleukemic globin heterodimer heterodimers holocomplex implicate lcr maf mafk mare mares mel multimeric multivalent nrf1 nucleoprotein obligate opening poz properly zipper
Tagcloud (Difference) ?		aminobutyric bioassay catalase cip1 cyp7a1 den deoxyguanosine diethylnitrosamine doses drinking exhibits f344 foci gaba gst hepatocarcinogenesis hydroxy modulating nrf2 placental powerful ppm sitchensis suppress suppressing transferase valerian valeriana waf1	architectural architecture bach2 bear btb bzip constitutes erythroleukemic globin heterodimer heterodimers holocomplex implicate lcr maf mafk mare mares mel multimeric multivalent nrf1 nucleoprotein obligate opening poz properly zipper
Tagcloud (Intersection) ?