RPP14 and CAPZB

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		RPP14	CAPZB
Gene Name		ribonuclease P/MRP 14kDa subunit	capping protein (actin filament) muscle Z-line, beta
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Cytosol Cytoskeleton Actin Filament F-actin Capping Protein Complex Actin Cytoskeleton Sarcomere Actin Cortical Patch Extracellular Vesicular Exosome WASH Complex
	Molecular Function	RNA Binding Ribonuclease P Activity	Actin Binding Actin Filament Binding
	Biological Process	TRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	Movement Of Cell Or Subcellular Component Cytoskeleton Organization Blood Coagulation Regulation Of Lamellipodium Assembly Regulation Of Cell Morphogenesis Actin Cytoskeleton Organization Barbed-end Actin Filament Capping Negative Regulation Of Filopodium Assembly
Pathways			Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS			Crohn's disease and psoriasis ( 22482804) Thyroid function ( 22494929) Thyroid hormone levels ( 23408906) Thyroid volume ( 21565293)
Protein-Protein Interactions		19 interactors: A2M ATP5B CAPZB DOCK7 EXOSC8 IGSF21 KMT2B LIMD1 MSH2 NOVA1 PKM POP4 POP5 PSME1 RPP25 RPP30 RPP38 RPP40 WIZ	7 interactors: BCCIP HSPA8 MRPL20 MTPN PTN RPP14 VHL
Entrez ID		11102	832
HPRD ID		18001	11872
Ensembl ID		ENSG00000163684	ENSG00000077549
Uniprot IDs		O95059	B1AK85 B1AK88 B4DWA6 P47756 Q7L4N0
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Phosphodiester Bond Hydrolysis, Endonucleolytic RNA Phosphodiester Bond Hydrolysis TRNA Processing TRNA Metabolic Process NcRNA Metabolic Process Nucleic Acid Phosphodiester Bond Hydrolysis Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Negative Regulation Of Reciprocal Meiotic Recombination Negative Regulation Of Complement Activation, Lectin Pathway Ribonucleoprotein Complex Biogenesis Meiotic Mismatch Repair Establishment Of Neuroblast Polarity Mitotic DNA Damage Checkpoint Cellular Metabolic Process Mitotic DNA Integrity Checkpoint Gene Silencing Meiotic Gene Conversion Maintenance Of DNA Repeat Elements Positive Regulation Of Gene Silencing By MiRNA Generation Of Precursor Metabolites And Energy Signal Transduction By P53 Class Mediator Positive Regulation Of Nuclear Cell Cycle DNA Replication	Negative Regulation Of Fibril Organization Regulation Of Fibril Organization Regulation Of Barbed-end Actin Filament Capping Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Protein Complex Disassembly Clathrin Coat Disassembly Protein Complex Disassembly Neuroendocrine Cell Differentiation
Tagcloud ?			actin align apolar capping capza2 cdnas chicken conservation cosedimentation divergence diverges gelsolin homologs leucines mapped monomer outside p36 polar portion q31 regularly severing shares spaced substitutions subunit
Tagcloud (Difference) ?			actin align apolar capping capza2 cdnas chicken conservation cosedimentation divergence diverges gelsolin homologs leucines mapped monomer outside p36 polar portion q31 regularly severing shares spaced substitutions subunit
Tagcloud (Intersection) ?