RPP14 and ZNF277

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RPP14	ZNF277
Description		ribonuclease P/MRP subunit p14	zinc finger protein 277
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Ribonuclease P Complex Multimeric Ribonuclease P Complex Endoribonuclease Complex Ribonucleoprotein Complex	Nucleus
	Molecular Function	RNA Binding Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	TRNA 5'-leader Removal TRNA Processing	Cellular Response To Hydrogen Peroxide Regulation Of Cellular Senescence
Pathways		tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Height ( 28552196) Hemoglobin levels ( 32327693) Mitochondrial heteroplasmy measurement ( 33731350) Platelet distribution width ( 32888494) Refractive error ( 32231278) Rheumatoid arthritis (ACPA-positive) ( 24532676) Total cholesterol levels ( 30275531)	Breast size ( 22747683) Early-onset Parkinson's disease ( 28256260) Refractive error ( 32231278)
Interacting Genes		22 interacting genes: A2M ACTN2 ATP5F1B CAPZB DOCK7 EXOSC8 GEMIN2 IGSF21 KMT2B LIMD1 MSH2 NOVA1 PKM POP4 POP5 PSME1 RPP25 RPP30 RPP38 RPP40 WIZ ZNF277	10 interacting genes: CDCA8 COIL DDB1 GNGT1 MBD3 NUTM1 OGT RPP14 ZBTB7B ZNF768
Entrez ID		11102	11179
HPRD ID		18001	05680
Ensembl ID		ENSG00000163684	ENSG00000198839
Uniprot IDs		O95059	Q9NRM2
PDB IDs		6AHR 6AHU
Enriched GO Terms of Interacting Partners?		Ribonuclease MRP Complex Ribonuclease P RNA Binding Multimeric Ribonuclease P Complex Ribonuclease P Activity TRNA 5'-leader Removal TRNA 5'-end Processing Nucleolar Ribonuclease P Complex TRNA Metabolic Process RRNA Processing Ribonuclease P Complex TRNA Processing RRNA Metabolic Process RNA Processing Nucleolus Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Nucleoplasm RNA Binding Nucleic Acid Metabolic Process Nucleus Actin Filament Uncapping Ribonuclease MRP Activity
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