RPP14 and RPP40

Number of citations of the paper that reports this interaction (PMID 15096576)
35

Data Source:
HPRD (in vitro)

		RPP14	RPP40
Gene Name		ribonuclease P/MRP 14kDa subunit	ribonuclease P/MRP 40kDa subunit
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleolar Ribonuclease P Complex
	Molecular Function	RNA Binding Ribonuclease P Activity	Ribonuclease P Activity
	Biological Process	TRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	TRNA Processing RNA Phosphodiester Bond Hydrolysis RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: A2M ATP5B CAPZB DOCK7 EXOSC8 IGSF21 KMT2B LIMD1 MSH2 NOVA1 PKM POP4 POP5 PSME1 RPP25 RPP30 RPP38 RPP40 WIZ	6 interactors: POP1 POP7 RPP14 RPP21 RPP30 RPP38
Entrez ID		11102	10799
HPRD ID		18001	09361
Ensembl ID		ENSG00000163684	ENSG00000124787
Uniprot IDs		O95059	O75818
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Phosphodiester Bond Hydrolysis, Endonucleolytic RNA Phosphodiester Bond Hydrolysis TRNA Processing TRNA Metabolic Process NcRNA Metabolic Process Nucleic Acid Phosphodiester Bond Hydrolysis Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Negative Regulation Of Reciprocal Meiotic Recombination Negative Regulation Of Complement Activation, Lectin Pathway Ribonucleoprotein Complex Biogenesis Meiotic Mismatch Repair Establishment Of Neuroblast Polarity Mitotic DNA Damage Checkpoint Cellular Metabolic Process Mitotic DNA Integrity Checkpoint Gene Silencing Meiotic Gene Conversion Maintenance Of DNA Repeat Elements Positive Regulation Of Gene Silencing By MiRNA Generation Of Precursor Metabolites And Energy Signal Transduction By P53 Class Mediator Positive Regulation Of Nuclear Cell Cycle DNA Replication	RNA Phosphodiester Bond Hydrolysis, Endonucleolytic RNA Phosphodiester Bond Hydrolysis TRNA Processing TRNA Metabolic Process Nucleic Acid Phosphodiester Bond Hydrolysis NcRNA Metabolic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process TRNA 5'-leader Removal Sinoatrial Node Cell Development TRNA Catabolic Process Sinoatrial Node Cell Differentiation Sinoatrial Node Development Cardiac Conduction System Development Positive Regulation Of Receptor Recycling Positive Regulation Of Interleukin-1 Beta Secretion Positive Regulation Of Interleukin-1 Secretion Regulation Of Rac GTPase Activity Regulation Of Interleukin-1 Beta Secretion Cellular Metabolic Process Regulation Of Cdc42 GTPase Activity Positive Regulation Of Interleukin-1 Beta Production Regulation Of Receptor Recycling Regulation Of Cdc42 Protein Signal Transduction Positive Regulation Of Interleukin-1 Production Tumor Necrosis Factor-mediated Signaling Pathway Epithelial Cell-cell Adhesion Regulation Of Rac Protein Signal Transduction Substrate Adhesion-dependent Cell Spreading
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