RPP14 and LIMD1

Number of citations of the paper that reports this interaction (PubMedID 11158571)
31

Data Source:
HPRD (two hybrid)

		RPP14	LIMD1
Description		ribonuclease P/MRP subunit p14	LIM domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Ribonuclease P Complex Multimeric Ribonuclease P Complex Endoribonuclease Complex Ribonucleoprotein Complex	P-body Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Cytosol Plasma Membrane Adherens Junction Focal Adhesion RISC Complex Anchoring Junction
	Molecular Function	RNA Binding Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding	Transcription Corepressor Activity Protein Binding Metal Ion Binding
	Biological Process	TRNA 5'-leader Removal TRNA Processing	Response To Hypoxia Osteoblast Development Regulation Of DNA-templated Transcription Cytoskeleton Organization Regulation Of Cell Shape Phosphorylation Cell Migration Regulatory NcRNA-mediated Gene Silencing P-body Assembly MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Hippo Signaling Negative Regulation Of Osteoblast Differentiation Negative Regulation Of DNA-templated Transcription Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways		tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol	Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Drugs
Diseases
GWAS		Height ( 28552196) Hemoglobin levels ( 32327693) Mitochondrial heteroplasmy measurement ( 33731350) Platelet distribution width ( 32888494) Refractive error ( 32231278) Rheumatoid arthritis (ACPA-positive) ( 24532676) Total cholesterol levels ( 30275531)	Acne (severe) ( 24927181) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Macular telangiectasia type 2 ( 33654266) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Systolic blood pressure ( 30578418)
Interacting Genes		22 interacting genes: A2M ACTN2 ATP5F1B CAPZB DOCK7 EXOSC8 GEMIN2 IGSF21 KMT2B LIMD1 MSH2 NOVA1 PKM POP4 POP5 PSME1 RPP25 RPP30 RPP38 RPP40 WIZ ZNF277	6 interacting genes: APP BRCA2 HIPK3 RPP14 STAC TRAF6
Entrez ID		11102	8994
HPRD ID		18001	05177
Ensembl ID		ENSG00000163684	ENSG00000144791
Uniprot IDs		O95059	Q9UGP4
PDB IDs		6AHR 6AHU
Enriched GO Terms of Interacting Partners?		Ribonuclease MRP Complex Ribonuclease P RNA Binding Multimeric Ribonuclease P Complex Ribonuclease P Activity TRNA 5'-leader Removal TRNA 5'-end Processing Nucleolar Ribonuclease P Complex TRNA Metabolic Process RRNA Processing Ribonuclease P Complex TRNA Processing RRNA Metabolic Process RNA Processing Nucleolus Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Nucleoplasm RNA Binding Nucleic Acid Metabolic Process Nucleus Actin Filament Uncapping Ribonuclease MRP Activity	Regulation Of JNK Cascade Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Response To Interleukin-1 Regulation Of Phosphorus Metabolic Process Growth Cone Lamellipodium Positive Regulation Of Mitotic Cell Cycle Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Positive Regulation Of Interleukin-6 Production Amylin Binding Positive Regulation Of JNK Cascade Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Myeloid Leukocyte Activation Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Mitotic Recombination-dependent Replication Fork Processing BRCA2-MAGE-D1 Complex Cytoplasmic Side Of Plasma Membrane Regulation Of MAP Kinase Activity MRNA Transcription Regulation Of Protein Serine/threonine Kinase Activity Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine Amidase Activity Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cell Maturation Regulation Of Interleukin-6 Production Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Regulation Of MAPK Cascade Low-density Lipoprotein Particle Mediated Signaling Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Regulation Of Protein Localization To Membrane Positive Regulation Of Voltage-gated Calcium Channel Activity Regulation Of Protein Localization To Cell Periphery Endoribonuclease Complex Ribonuclease P Complex
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