DIDO1 and ARAF

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		DIDO1	ARAF
Gene Name		death inducer-obliterator 1	A-Raf proto-oncogene, serine/threonine kinase
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Spindle	Cellular_component
	Molecular Function	Zinc Ion Binding Poly(A) RNA Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Receptor Signaling Protein Activity Protein Binding ATP Binding Metal Ion Binding
	Biological Process	Transcription, DNA-templated Apoptotic Signaling Pathway	Cellular Protein Modification Process Protein Phosphorylation Regulation Of TOR Signaling Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Peptidyl-serine Phosphorylation Intracellular Signal Transduction Negative Regulation Of Apoptotic Process
Pathways
Drugs			Adenosine triphosphate
Diseases
GWAS
Protein-Protein Interactions		9 interactors: APP ARAF DVL3 HIST3H3 HNRNPK KCNK4 SRSF1 WWP1 WWP2	38 interactors: AGTRAP ASS1 BAD CHD6 COPS3 CPS1 CSNK2B DIDO1 E2F6 EFEMP1 GNA12 HRAS IRAK2 IRF7 KLHL12 KRAS MAP2K1 MAP2K2 MLH1 MYO18A NELFCD NUDT14 PBK PDGFRB PIK3R1 PKM PRPF6 RABGGTB RGS12 RRAS RRAS2 TEKT4P2 TESK1 TIMM44 TIRAP WNK1 YWHAG YWHAZ
Entrez ID		11083	369
HPRD ID		10363	02405
Ensembl ID		ENSG00000101191	ENSG00000078061
Uniprot IDs		Q9BTC0	B4DV85 P10398 Q96II5
PDB IDs		2M3H 4L7X	1WXM
Enriched GO Terms of Interacting Partners?		Viral Entry Into Host Cell Entry Into Host Cell Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Nitrogen Compound Metabolic Process MRNA 3'-end Processing MRNA Processing Regulation Of Protein Metabolic Process Interaction With Host RNA 3'-end Processing Positive Regulation Of Protein Metabolic Process Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Synaptic Growth At Neuromuscular Junction MRNA Metabolic Process Viral Process RNA Processing Collateral Sprouting In Absence Of Injury Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Regulation Of Transcription, DNA-templated Collateral Sprouting Axon Midline Choice Point Recognition Non-canonical Wnt Signaling Pathway Via JNK Cascade MRNA 5'-splice Site Recognition Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Non-canonical Wnt Signaling Pathway Via MAPK Cascade Viral Life Cycle Axon Choice Point Recognition Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Neuron Remodeling Regulation Of Gene Expression Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Low-density Lipoprotein Particle Clearance Positive Regulation Of Receptor Biosynthetic Process Proteasomal Protein Catabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Translation Planar Cell Polarity Pathway Involved In Neural Tube Closure Regulation Of Establishment Of Planar Polarity Involved In Neural Tube Closure Regulation Of Metabolic Process Outflow Tract Septum Morphogenesis Regulation Of Protein Phosphorylation Regulation Of Receptor Biosynthetic Process MRNA Cis Splicing, Via Spliceosome Positive Regulation Of Cellular Protein Metabolic Process Cellular Copper Ion Homeostasis RNA Splicing	Intracellular Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Immune Response-regulating Signaling Pathway Cellular Response To Stimulus Regulation Of Phosphorylation Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Regulation Of Kinase Activity Cellular Response To Peptide Hormone Stimulus Innate Immune Response Signal Transduction Positive Regulation Of Signal Transduction Regulation Of Cell Motility Regulation Of Signal Transduction Cellular Response To Peptide Cellular Response To Organonitrogen Compound Immune Response Neurotrophin TRK Receptor Signaling Pathway Ras Protein Signal Transduction Neurotrophin Signaling Pathway Regulation Of Locomotion Fc-epsilon Receptor Signaling Pathway Regulation Of Cellular Component Movement Signaling Response To Hormone Regulation Of Signaling Cell Communication Toll-like Receptor 4 Signaling Pathway Fc Receptor Signaling Pathway Cellular Response To Hormone Stimulus Regulation Of Cell Migration Phosphorylation Response To Stimulus Regulation Of MAPK Cascade Response To Oleic Acid Intrinsic Apoptotic Signaling Pathway Response To Peptide Hormone Defense Response Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Immune Response Response To Peptide Positive Regulation Of Cell Motility Toll-like Receptor Signaling Pathway Apoptotic Signaling Pathway Positive Regulation Of Cellular Component Movement Positive Regulation Of MAP Kinase Activity Cellular Response To Insulin Stimulus
Tagcloud ?		20q 20q11 abnormality amplification arm band breakpoints chromosome consistently del deleted distal explain favourable hck hybridization ider interstitial isochromosome material myelodysplastic possibly proximal regions retained tnfrsf6b tumour variable variant	al augmentation braf craf1 die differentiated disruption dramatically drosophila elegans embryos enlarged establish failed finding gestation interacts mek membranes mid mutagenesis programmed ras signalling unlike unpublished vessels w
Tagcloud (Difference) ?		20q 20q11 abnormality amplification arm band breakpoints chromosome consistently del deleted distal explain favourable hck hybridization ider interstitial isochromosome material myelodysplastic possibly proximal regions retained tnfrsf6b tumour variable variant	al augmentation braf craf1 die differentiated disruption dramatically drosophila elegans embryos enlarged establish failed finding gestation interacts mek membranes mid mutagenesis programmed ras signalling unlike unpublished vessels w
Tagcloud (Intersection) ?