CPSF6 and SRSF7

Number of citations of the paper that reports this interaction (PMID 16055720)
52

Data Source:
HPRD (in vitro, in vivo)

		CPSF6	SRSF7
Gene Name		cleavage and polyadenylation specific factor 6, 68kDa	serine/arginine-rich splicing factor 7
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm MRNA Cleavage Factor Complex Membrane Ribonucleoprotein Complex Paraspeckles	Nucleus Nucleoplasm Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Nucleotide Binding RNA Binding MRNA Binding Protein Binding Poly(A) RNA Binding	Nucleotide Binding Protein Binding Zinc Ion Binding Poly(A) RNA Binding
	Biological Process	MRNA Polyadenylation MRNA Processing Protein Tetramerization	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Processing MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways		Signaling by FGFR in disease Signaling by FGFR1 mutants Signaling by FGFR mutants Signaling by FGFR1 fusion mutants	mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing
Drugs
Diseases
GWAS		Height ( 18391951)
Protein-Protein Interactions		23 interactors: APBB1 ARMC7 CSNK2A1 EWSR1 GIN1 ITCH ITSN2 KLHL12 NCK2 NEDD4 NUDT21 OTUB2 PLSCR1 PPIL1 PRPF40A SRSF7 TCERG1 TOLLIP UBAC1 UBQLN4 WBP4 WWP1 WWP2	13 interactors: CCNL2 CDK19 CDK6 CPSF6 DUSP11 LUC7L2 NEDD4 NXF1 PCBP2 SDCBP SREK1 SRPK1 SRPK2
Entrez ID		11052	6432
HPRD ID		05401	08991
Ensembl ID		ENSG00000111605	ENSG00000115875
Uniprot IDs		B4DSU9 Q16630	C9JAB2 Q16629
PDB IDs		3P5T 3P6Y 3Q2S 3Q2T 4B4N	2HVZ
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Interaction With Host Protein K63-linked Ubiquitination Viral Entry Into Host Cell Entry Into Host Cell Locomotion Protein Ubiquitination RNA Splicing Protein Modification By Small Protein Conjugation Cellular Metabolic Process MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Processing RNA Metabolic Process Cellular Protein Modification Process Regulation Of Potassium Ion Transmembrane Transporter Activity Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Catabolic Process Gene Expression Protein Polyubiquitination Regulation Of Potassium Ion Transmembrane Transport Termination Of RNA Polymerase II Transcription Viral Life Cycle Protein Monoubiquitination Regulation Of RNA Metabolic Process Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Negative Regulation Of Thymidylate Synthase Biosynthetic Process Transmission Of Virus Development Involved In Symbiotic Interaction Nucleobase-containing Compound Metabolic Process Positive Regulation Of Protein Catabolic Process Modification-dependent Protein Catabolic Process Viral Process Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Potassium Ion Transport Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Protein Catabolic Process Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of Endoplasmic Reticulum Stress-induced EIF2 Alpha Phosphorylation Regulation Of Nitrogen Compound Metabolic Process DNA-templated Transcription, Termination Protein Catabolic Process Cellular Nitrogen Compound Metabolic Process MRNA 3'-end Processing Regulation Of Protein Metabolic Process	RNA Processing MRNA Processing MRNA Metabolic Process RNA Splicing Gene Expression Positive Regulation Of Viral Genome Replication RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of Viral Genome Replication Spliceosomal Complex Assembly Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Cell Dedifferentiation Nuclear Speck Organization Transmission Of Virus Development Involved In Symbiotic Interaction Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Negative Regulation Of Viral Process Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Processing Regulation Of Cell Cycle Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of RNA Splicing Polynucleotide 5' Dephosphorylation Cellular Nitrogen Compound Metabolic Process Nucleus Organization Positive Regulation Of Extracellular Vesicular Exosome Assembly Cellular Metabolic Process Viral Process Regulation Of Extracellular Vesicular Exosome Assembly Progesterone Receptor Signaling Pathway Regulation Of Viral Process Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Ribonucleoprotein Complex Assembly Cellular Protein Metabolic Process Immune Response Immune System Process Cellular Protein Modification Process Protein Phosphorylation Glucocorticoid Receptor Signaling Pathway Sperm Chromatin Condensation Poly(A)+ MRNA Export From Nucleus Negative Regulation Of Cellular Senescence Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Protein Targeting To Lysosome
Tagcloud ?		abilities assembled believe bi bi2 ca cai capsid complexes core crowding cyclophilin cyclosporine destabilize destabilized destabilizes extracts fate hiv ixn macromolecular nc pf74 powerful productive solely stability stabilize stabilized
Tagcloud (Difference) ?		abilities assembled believe bi bi2 ca cai capsid complexes core crowding cyclophilin cyclosporine destabilize destabilized destabilizes extracts fate hiv ixn macromolecular nc pf74 powerful productive solely stability stabilize stabilized
Tagcloud (Intersection) ?