SRSF7 and CCNL2

Number of citations of the paper that reports this interaction (PMID 14684736)
14

Data Source:
HPRD (in vivo)

		SRSF7	CCNL2
Gene Name		serine/arginine-rich splicing factor 7	cyclin L2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Extracellular Vesicular Exosome	Nucleus Nucleoplasm Nucleolus Nuclear Speck Cell Junction Intracellular Membrane-bounded Organelle
	Molecular Function	Nucleotide Binding Protein Binding Zinc Ion Binding Poly(A) RNA Binding	Protein Kinase Binding
	Biological Process	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Processing MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing Negative Regulation Of MRNA Splicing, Via Spliceosome	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Transcription, DNA-templated Regulation Of Transcription, DNA-templated RNA Processing
Pathways		mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: CCNL2 CDK19 CDK6 CPSF6 DUSP11 LUC7L2 NEDD4 NXF1 PCBP2 SDCBP SREK1 SRPK1 SRPK2	6 interactors: CDK11B DYRK1A POLR2A RUNDC3A SRSF2 SRSF7
Entrez ID		6432	81669
HPRD ID		08991	10815
Ensembl ID		ENSG00000115875	ENSG00000221978
Uniprot IDs		C9JAB2 Q16629	Q96S94
PDB IDs		2HVZ
Enriched GO Terms of Interacting Partners?		RNA Processing MRNA Processing MRNA Metabolic Process RNA Splicing Gene Expression Positive Regulation Of Viral Genome Replication RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of Viral Genome Replication Spliceosomal Complex Assembly Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Cell Dedifferentiation Nuclear Speck Organization Transmission Of Virus Development Involved In Symbiotic Interaction Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Negative Regulation Of Viral Process Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Processing Regulation Of Cell Cycle Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of RNA Splicing Polynucleotide 5' Dephosphorylation Cellular Nitrogen Compound Metabolic Process Nucleus Organization Positive Regulation Of Extracellular Vesicular Exosome Assembly Cellular Metabolic Process Viral Process Regulation Of Extracellular Vesicular Exosome Assembly Progesterone Receptor Signaling Pathway Regulation Of Viral Process Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Ribonucleoprotein Complex Assembly Cellular Protein Metabolic Process Immune Response Immune System Process Cellular Protein Modification Process Protein Phosphorylation Glucocorticoid Receptor Signaling Pathway Sperm Chromatin Condensation Poly(A)+ MRNA Export From Nucleus Negative Regulation Of Cellular Senescence Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Protein Targeting To Lysosome	Regulation Of MRNA Processing Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Termination Of RNA Polymerase II Transcription RNA Splicing Regulation Of Nitrogen Compound Metabolic Process MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus MRNA 3'-end Processing MRNA Metabolic Process RNA Processing RNA 3'-end Processing Nuclear Export MRNA Transport Transcription, RNA-templated RNA Transport RNA Localization Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Nucleocytoplasmic Transport Nuclear Transport Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Guanylate Cyclase Activity Positive Regulation Of CGMP Biosynthetic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of CGMP Metabolic Process Negative Regulation Of RNA Splicing Regulation Of CGMP Biosynthetic Process Negative Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Protein Deacetylation Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of CGMP Metabolic Process 7-methylguanosine MRNA Capping PiRNA Metabolic Process Positive Regulation Of RNA Splicing 7-methylguanosine RNA Capping Transcription-coupled Nucleotide-excision Repair Regulation Of Signal Transduction By P53 Class Mediator Peptidyl-threonine Phosphorylation Positive Regulation Of Viral Transcription Cytoplasmic Transport Positive Regulation Of Lyase Activity Regulation Of Protein Deacetylation Mitotic Cell Cycle
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