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CPSF6 and MIR19A
Number of citations of the paper that reports this interaction (PubMedID
28431233
)
0
Data Source:
BioGRID
(unspecified method)
CPSF6
MIR19A
Description
cleavage and polyadenylation specific factor 6
microRNA 19a
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Perichromatin Fibrils
Cytoplasm
MRNA Cleavage And Polyadenylation Specificity Factor Complex
MRNA Cleavage Factor Complex
Membrane
Nuclear Speck
Interchromatin Granule
Paraspeckles
Ribonucleoprotein Complex
Extracellular Space
RISC Complex
Extracellular Exosome
Extracellular Vesicle
Molecular Function
Nucleic Acid Binding
RNA Binding
MRNA Binding
Protein Binding
Ribosomal Large Subunit Binding
Exon-exon Junction Complex Binding
MRNA 3'-UTR Binding
MRNA Base-pairing Post-transcriptional Repressor Activity
Biological Process
MRNA Processing
MRNA 3'-end Processing
Positive Regulation Of RNA Export From Nucleus
Protein Tetramerization
Protein Heterotetramerization
MRNA Alternative Polyadenylation
Co-transcriptional MRNA 3'-end Processing, Cleavage And Polyadenylation Pathway
Negative Regulation Of Inflammatory Response To Antigenic Stimulus
Negative Regulation Of Gene Expression
Negative Regulation Of Cardiac Muscle Cell Apoptotic Process
Negative Regulation Of Fibroblast Migration
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Interleukin-6 Production
Negative Regulation Of Toll-like Receptor Signaling Pathway
MiRNA-mediated Post-transcriptional Gene Silencing
MiRNA-mediated Gene Silencing By MRNA Destabilization
B Cell Activation
Negative Regulation Of Apoptotic Process
Negative Regulation Of Inflammatory Response
Positive Regulation Of B Cell Receptor Signaling Pathway
Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development
Negative Regulation Of Cardiac Epithelial To Mesenchymal Transition
Cellular Response To Bacterial Lipopeptide
Negative Regulation Of Extracellular Matrix Assembly
Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Sprouting Angiogenesis
Regulation Of Cardiac Conduction
Negative Regulation Of Cellular Response To Transforming Growth Factor Beta Stimulus
Negative Regulation Of Matrix Metallopeptidase Secretion
Pathways
Signaling by cytosolic FGFR1 fusion mutants
Signaling by FGFR1 in disease
Drugs
Diseases
GWAS
Height (
18391951
)
Medication use (agents acting on the renin-angiotensin system) (
31015401
)
Medication use (diuretics) (
31015401
)
Pneumoconiosis in silica exposure (
24986923
)
Smoking initiation (
33082346
)
Smoking initiation (ever regular vs never regular) (
30679032
)
Smoking status (ever vs never smokers) (
30643258
)
Interacting Genes
50 interacting genes:
APBB1
ARMC7
CEBPA
CSNK2A1
EWSR1
FOXP1
GIN1
ITCH
ITSN2
KLHL12
MIR10B
MIR128-1
MIR128-2
MIR138-2
MIR155
MIR17
MIR18B
MIR199A1
MIR19A
MIR19B1
MIR19B2
MIR25
MIR29A
MIR34A
MIR92A1
MIR93
MIRLET7A1
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7F2
NCK2
NEDD4
NUDT21
OGT
OTUB2
PLSCR1
PPIL1
PRPF40A
SRSF7
TOLLIP
UBAC1
UBQLN4
USP21
WBP4
WWOX
WWP1
WWP2
YES1
ZMYND19
99 interacting genes:
AGO2
AIMP2
APOBEC3B
ATXN2L
C1QBP
CELF1
CELF2
CPSF1
CPSF2
CPSF3
CPSF4
CPSF6
CPSF7
CRTAP
CSTF2
CSTF3
DARS1
DDX1
DDX21
DDX3X
DHX36
EIF2AK2
EPRS1
ERAL1
FAM98A
FIP1L1
FUS
G3BP2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LIN28A
LRPPRC
MARS1
MATR3
MSI1
MSI2
NOL6
NONO
NUDT21
NUFIP2
P3H1
PDCD11
PLOD1
PRMT1
PTBP1
PTBP3
PUF60
PURA
QARS1
RARS1
RBBP6
RBFOX2
RBM12B
RBM14
RBM4
RBMS2
RTCB
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SUGP2
SYMPK
SYNCRIP
TAF15
TRA2A
TRA2B
U2SURP
UPF1
UTP20
WDR33
WWP1
WWP2
YBX1
YBX2
YBX3
ZFR
ZNF346
ZNF385A
Entrez ID
11052
406979
HPRD ID
05401
Ensembl ID
ENSG00000111605
ENSG00000284204
Uniprot IDs
Q16630
PDB IDs
3P5T
3P6Y
3Q2S
3Q2T
4B4N
4U0A
4U0B
4WYM
6AY9
6GX9
7SNQ
7ZUD
8CL1
8EJL
8GDV
9CNV
Enriched GO Terms of Interacting Partners
?
RISC Complex
MiRNA-mediated Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Post-transcriptional Gene Silencing
Post-transcriptional Gene Silencing
MRNA Base-pairing Post-transcriptional Repressor Activity
Regulatory NcRNA-mediated Gene Silencing
Post-transcriptional Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Extracellular Vesicle
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Metabolic Process
MRNA 3'-UTR Binding
Regulation Of Gene Expression
MiRNA-mediated Gene Silencing By MRNA Destabilization
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Macromolecule Metabolic Process
MiRNA-mediated Gene Silencing By Inhibition Of Translation
Regulation Of Metabolic Process
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Cell Migration
Negative Regulation Of Translation
Negative Regulation Of Cell Motility
Negative Regulation Of Signal Transduction
Negative Regulation Of Locomotion
MRNA Destabilization
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
RNA Destabilization
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Positive Regulation Of MRNA Catabolic Process
Negative Regulation Of Cytokine Production
Regulation Of Cellular Response To Growth Factor Stimulus
Regulation Of Cardiac Muscle Hypertrophy
Negative Regulation Of Cholesterol Efflux
Negative Regulation Of Vascular Endothelial Growth Factor Production
Regulation Of Endothelial Cell Migration
Negative Regulation Of Multicellular Organismal Process
Positive Regulation Of MRNA Metabolic Process
Regulation Of Translation
Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development
Negative Regulation Of Developmental Process
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Cardiac Muscle Cell Apoptotic Process
Negative Regulation Of Transport
Negative Regulation Of Cholesterol Transport
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Negative Regulation Of Matrix Metallopeptidase Secretion
RNA Binding
Nucleic Acid Binding
RNA Processing
RNA Metabolic Process
MRNA Processing
MRNA Metabolic Process
Nucleic Acid Metabolic Process
Nucleobase-containing Compound Metabolic Process
RNA Splicing
MRNA Binding
Nucleus
Macromolecule Metabolic Process
Regulation Of RNA Splicing
Regulation Of MRNA Metabolic Process
Ribonucleoprotein Complex
MRNA Cleavage And Polyadenylation Specificity Factor Complex
Nucleoplasm
Post-transcriptional Regulation Of Gene Expression
MRNA Splicing, Via Spliceosome
Regulation Of Translation
RNA Splicing, Via Transesterification Reactions
MRNA 3'-UTR Binding
Regulation Of MRNA Processing
Regulation Of MRNA Splicing, Via Spliceosome
Aminoacyl-tRNA Synthetase Multienzyme Complex
Cytoplasmic Stress Granule
Spliceosomal Complex
MiRNA Binding
Negative Regulation Of MRNA Metabolic Process
Catalytic Step 2 Spliceosome
Negative Regulation Of Translation
Negative Regulation Of RNA Catabolic Process
RNA Stabilization
RNA 3'-end Processing
Regulation Of Alternative MRNA Splicing, Via Spliceosome
MRNA 3'-end Processing
Co-transcriptional RNA 3'-end Processing, Cleavage And Polyadenylation Pathway
Regulation Of Gene Expression
Regulation Of Macromolecule Metabolic Process
Regulation Of Primary Metabolic Process
Negative Regulation Of MRNA Catabolic Process
Regulation Of Macromolecule Biosynthetic Process
Regulation Of MRNA Stability
MRNA Stabilization
Regulation Of RNA Stability
Pre-mRNA Binding
Positive Regulation Of Cytoplasmic Translation
Co-transcriptional MRNA 3'-end Processing, Cleavage And Polyadenylation Pathway
Regulation Of Metabolic Process
Regulation Of Cytoplasmic Translation
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