ADIRF and RPS6KA6

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		ADIRF	RPS6KA6
Gene Name		adipogenesis regulatory factor	ribosomal protein S6 kinase, 90kDa, polypeptide 6
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Extracellular Vesicular Exosome	Nucleus Nucleoplasm Nucleolus Mitochondrion Cytosol
	Molecular Function	Molecular_function	Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity ATP Binding
	Biological Process	Transcription, DNA-templated Cell Differentiation Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Radiation Cellular Response To Cisplatin Regulation Of Response To Drug	Protein Phosphorylation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Signal Transduction Synaptic Transmission Axon Guidance Central Nervous System Development Negative Regulation Of Embryonic Development Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Mesoderm Development
Pathways			Axon guidance RSK activation Activation of NMDA receptor upon glutamate binding and postsynaptic events L1CAM interactions Recycling pathway of L1 CREB phosphorylation through the activation of Ras Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Transmission across Chemical Synapses Post NMDA receptor activation events
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: GSK3B RPS6KA6	28 interactors: ADIRF APP C14orf1 CEBPZ CENPB CLEC3B DHX34 DNAJC13 DNMT1 FBN3 FZD5 LMO4 MAPK3 MASP1 MED24 MICAL1 MPP1 NR4A1 RBPJ RPLP1 RXRA SAP30BP SPTBN4 SYNE4 UBE2I UFM1 ZNF227 ZNF746
Entrez ID		10974	27330
HPRD ID		16575	02250
Ensembl ID		ENSG00000148671
Uniprot IDs		Q15847 Q5TBU5	Q9UK32
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of MAPK Cascade Negative Regulation Of Type B Pancreatic Cell Development Superior Temporal Gyrus Development Re-entry Into Mitotic Cell Cycle Negative Regulation Of Neuron Maturation Axon Guidance Negative Regulation Of Phosphorylation Hypermethylation Of CpG Island Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Negative Regulation Of Intracellular Signal Transduction Cellular Response To Interleukin-3 Axonogenesis Negative Regulation Of Mesoderm Development Regulation Of Neuron Maturation Negative Regulation Of Glycogen (starch) Synthase Activity Axon Development Protein Localization To Microtubule Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Negative Regulation Of Dendrite Morphogenesis Regulation Of MAPK Cascade Negative Regulation Of NFAT Protein Import Into Nucleus Neuron Projection Morphogenesis ER Overload Response Negative Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Muscle Hypertrophy Regulation Of Glycogen (starch) Synthase Activity Cell Morphogenesis Involved In Differentiation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Positive Regulation Of Protein Export From Nucleus Neuron Projection Development Regulation Of Type B Pancreatic Cell Development Cell Projection Morphogenesis Positive Regulation Of Peptidyl-threonine Phosphorylation Negative Regulation Of Dendrite Development Cell Part Morphogenesis Neuron Development Regulation Of DNA Methylation Central Nervous System Development Myoblast Fusion Protein Localization To Cytoskeleton Cell Morphogenesis Negative Regulation Of Signal Transduction Neuron Differentiation Regulation Of Gene Expression By Genetic Imprinting Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cell Projection Organization Response To Lithium Ion	Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Gene Expression Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Positive Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process DNA-templated Transcription, Initiation Positive Regulation Of Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Intracellular Receptor Signaling Pathway Regulation Of Protein Metabolic Process Regulation Of Protein Processing Regulation Of Early Endosome To Late Endosome Transport Cell Differentiation Biosynthetic Process Cardiac Ventricle Development Negative Regulation Of Cellular Metabolic Process Labyrinthine Layer Blood Vessel Development Sterol Metabolic Process Tissue Development Cardiac Chamber Development Neuron Maturation Regulation Of Cell Fate Commitment Apoptotic Process Cell Maturation Negative Regulation Of Protein Processing Regulation Of Cellular Process Tissue Morphogenesis Programmed Cell Death Placenta Blood Vessel Development
Tagcloud ?			anchorage anticipated attribution azacytidine cdna chemoresponse clines codons deleted demethylation depended duplet encompass exclude exon immunoblots indolocarbazole isoforms nt nucleotides penultimate rsk4 situation sparse splice starvation suppressive triplet uncharacterized
Tagcloud (Difference) ?			anchorage anticipated attribution azacytidine cdna chemoresponse clines codons deleted demethylation depended duplet encompass exclude exon immunoblots indolocarbazole isoforms nt nucleotides penultimate rsk4 situation sparse splice starvation suppressive triplet uncharacterized
Tagcloud (Intersection) ?