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PTGES3 and DNAJB1
Number of citations of the paper that reports this interaction (PubMedID
11809754
)
0
Data Source:
HPRD
(in vitro)
PTGES3
DNAJB1
Description
prostaglandin E synthase 3
DnaJ heat shock protein family (Hsp40) member B1
Image
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Nucleus
Nucleoplasm
Telomerase Holoenzyme Complex
Cytoplasm
Cytosol
Protein-containing Complex
Protein Folding Chaperone Complex
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Postsynaptic Density
Neuronal Cell Body
Dendritic Spine
Sperm Head
Extracellular Exosome
Postsynapse
Glutamatergic Synapse
Molecular Function
Telomerase Activity
Protein Binding
Isomerase Activity
Prostaglandin-E Synthase Activity
Unfolded Protein Binding
Protein-folding Chaperone Binding
Hsp90 Protein Binding
DNA Polymerase Binding
ATPase Activator Activity
Transcription Corepressor Activity
Protein Binding
Hsp70 Protein Binding
Protein Folding Chaperone
Cadherin Binding
Unfolded Protein Binding
Protein-folding Chaperone Binding
ATPase Binding
Transcription Regulator Inhibitor Activity
Biological Process
Telomere Maintenance
Prostaglandin Biosynthetic Process
Protein Folding
Lipid Metabolic Process
Fatty Acid Metabolic Process
Fatty Acid Biosynthetic Process
Prostaglandin Metabolic Process
Telomere Maintenance Via Telomerase
Signal Transduction
Positive Regulation Of Telomere Maintenance Via Telomerase
Prostanoid Biosynthetic Process
Protein Stabilization
Chaperone-mediated Protein Complex Assembly
Telomerase Holoenzyme Complex Assembly
Negative Regulation Of Transcription By RNA Polymerase II
Protein Folding
Response To Unfolded Protein
Forebrain Development
Cellular Response To Heat
Negative Regulation Of Inclusion Body Assembly
Regulation Of Cellular Response To Heat
Positive Regulation Of Protein Folding
Pathways
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
HSF1 activation
Attenuation phase
Aryl hydrocarbon receptor signalling
ESR-mediated signaling
Estrogen-dependent gene expression
Potential therapeutics for SARS
Regulation of HSF1-mediated heat shock response
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
Attenuation phase
HSF1-dependent transactivation
MAPK6/MAPK4 signaling
Drugs
Acetaminophen
Grn163l
Copper
Diseases
GWAS
Alanine aminotransferase levels (
33547301
)
Asthma (
31619474
)
High light scatter reticulocyte count (
32888494
)
High light scatter reticulocyte percentage of red cells (
27863252
)
Liver enzyme levels (alanine transaminase) (
33972514
)
Mean platelet volume (
22139419
)
Platelet count (
22139419
)
Reticulocyte count (
32888494
)
Adventurousness (
30643258
)
General risk tolerance (MTAG) (
30643258
)
Interacting Genes
30 interacting genes:
AHR
AHSA1
AIP
ARNT
CASP3
CASP7
CAV3
CD2AP
CDC37
COPG1
COPG2
DNAJB1
DNMT3A
EIF2AK2
ERBB3
ESR1
FES
GZMB
HSF1
HSP90AA1
HSPA1A
HSPB1
MAPT
NR3C1
NR3C2
SIM2
STIP1
SURF1
TERT
THRA
33 interacting genes:
A2M
AKT1
ANK2
APP
BDKRB1
BRCA1
BRMS1
CEBPA
CENPE
CYP2C8
DNAJC3
DYRK3
ECSIT
FANCA
FANCC
GLB1
GSK3A
HSF1
HSPA1A
MAST1
NQO1
NRAS
PEA15
PLEKHO1
PPDPF
PSEN2
PTGES3
SOD1
SPP1
STUB1
TERF1
TTLL12
ZFP36
Entrez ID
10728
3337
HPRD ID
06138
05198
Ensembl ID
ENSG00000110958
ENSG00000132002
Uniprot IDs
A0A087WYT3
B3KUY2
Q15185
P25685
Q6FHS4
PDB IDs
1EJF
7KRJ
7L7I
7L7J
1HDJ
2QLD
3AGX
3AGY
3AGZ
4WB7
6BYR
6WJF
6WJG
6Z5N
7NDX
8FE2
8FE5
8FEC
Enriched GO Terms of Interacting Partners
?
Hsp90 Protein Binding
Nuclear Receptor Activity
TBP-class Protein Binding
Unfolded Protein Binding
Response To Temperature Stimulus
Response To Heat
Regulation Of Gene Expression
Cellular Response To Heat
Regulation Of Macromolecule Biosynthetic Process
Response To Lipid
Protein Folding Chaperone
Regulation Of Macromolecule Metabolic Process
Aryl Hydrocarbon Receptor Complex
Regulation Of Apoptotic Process
Protein Folding Chaperone Complex
Cytoplasm
Positive Regulation Of Microtubule Polymerization
Positive Regulation Of Protein Polymerization
Response To Unfolded Protein
Regulation Of Programmed Cell Death
Regulation Of Primary Metabolic Process
Intracellular Signal Transduction
Regulation Of Metabolic Process
Cytosol
Response To Stress
Regulation Of Protein-containing Complex Assembly
Estrogen Response Element Binding
Negative Regulation Of Macromolecule Biosynthetic Process
Cellular Response To Lipid
Protein-folding Chaperone Binding
Negative Regulation Of Inclusion Body Assembly
Protein Folding
Negative Regulation Of Biosynthetic Process
Animal Organ Development
Regulation Of Cellular Response To Heat
Intracellular Receptor Signaling Pathway
Nuclear Aryl Hydrocarbon Receptor Complex
Neurofibrillary Tangle Assembly
Protein-containing Complex
Regulation Of Neuron Apoptotic Process
Regulation Of Microtubule Polymerization
Regulation Of Inclusion Body Assembly
Negative Regulation Of Macromolecule Metabolic Process
Regulation Of Multicellular Organismal Process
Response To Hormone
Positive Regulation Of Metabolic Process
Response To Hypoxia
Sequence-specific DNA Binding
Cellular Response To Oxygen-containing Compound
DNA-binding Transcription Factor Activity
Enzyme Binding
Regulation Of Programmed Cell Death
Regulation Of Growth
Regulation Of Apoptotic Process
Intracellular Signal Transduction
Response To Temperature Stimulus
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Response To Heat
Cellular Response To Metal Ion
Protein-folding Chaperone Binding
Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Response To Lipid
Regulation Of Developmental Growth
Positive Regulation Of Proteolysis
Positive Regulation Of Proteasomal Protein Catabolic Process
Positive Regulation Of Protein Catabolic Process
Response To Steroid Hormone
Intracellular Signaling Cassette
Misfolded Protein Binding
Positive Regulation Of Macromolecule Metabolic Process
Cytoplasm
Negative Regulation Of Programmed Cell Death
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Proteolysis Involved In Protein Catabolic Process
Regulation Of Protein Catabolic Process
Regulation Of Cellular Response To Stress
Positive Regulation Of Apoptotic Process
Heat Shock Protein Binding
Regulation Of Apoptotic Signaling Pathway
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Catabolic Process
Response To Peptide
Regulation Of Cell Growth
Protein-containing Complex
Positive Regulation Of Gene Expression
Regulation Of Extrinsic Apoptotic Signaling Pathway
Negative Regulation Of Cell Growth
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Metabolic Process
Response To Hormone
Cellular Response To Topologically Incorrect Protein
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Regulation Of Defense Response
Regulation Of Cell Development
Signal Transduction
Regulation Of Cell Cycle
Response To Stress
Regulation Of Cellular Component Organization
Regulation Of Immune System Process
Negative Regulation Of Apoptotic Process
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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