TCERG1 and DNAJB9

Number of citations of the paper that reports this interaction (PubMedID 15456888)
53

Data Source:
HPRD (in vitro)

		TCERG1	DNAJB9
Description		transcription elongation regulator 1	DnaJ heat shock protein family (Hsp40) member B9
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck	Nucleolus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Extracellular Exosome
	Molecular Function	Transcription Elongation Factor Activity Transcription Coregulator Activity Transcription Coactivator Activity Transcription Corepressor Activity RNA Binding Protein Binding Identical Protein Binding Ubiquitin-like Protein Conjugating Enzyme Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding RNA Polymerase Binding	Protein Binding Hsp70 Protein Binding Protein-folding Chaperone Binding Misfolded Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II MRNA Processing RNA Splicing Positive Regulation Of Transcription Elongation By RNA Polymerase II Negative Regulation Of Transcription Elongation By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	Positive Regulation Of Immunoglobulin Production Response To Unfolded Protein B Cell Differentiation Response To Endoplasmic Reticulum Stress ERAD Pathway Negative Regulation Of IRE1-mediated Unfolded Protein Response
Pathways		mRNA Splicing - Major Pathway	XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS		Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)	Body size at age 10 ( 32376654) Metabolite levels ( 23823483) Smoking behavior ( 22006218)
Interacting Genes		56 interacting genes: ABI1 AURKA BARD1 CEBPA CHAF1A CHD3 CYFIP1 CYFIP2 DIAPH1 DIAPH2 DNAJB9 ESR1 EVL FANCA FANCC FMNL1 GRB2 HNRNPH1 HNRNPK HNRNPM HNRNPU HSPA1A HSPA5 HSPA8 HTT JUNB LUC7L NONO NPM1 NUDT21 PCBP1 PIAS4 POLR2A PSPC1 RNF10 RUNX1 SETDB1 SF1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SRSF1 SUMO2 TPM4 U2AF2 UBE2I WAS WASF2 WBP4 WIPF2 WWOX	11 interacting genes: DYNLL1 ECPAS FSCN1 GARIN6 GRIK1 MYL6 PLK1 RFK SLC16A8 TCEA2 TCERG1
Entrez ID		10915	4189
HPRD ID		10393	07047
Ensembl ID		ENSG00000113649	ENSG00000128590
Uniprot IDs		A0A7P0T8N8 O14776	Q6FIF1 Q9UBS3
PDB IDs		2DK7 2DOD 2DOE 2DOF 2E71 2KIQ 2KIS 2MW9 2MWA 2MWB 2MWD 2MWE 2MWF 2N4R 2N4S 2N4T 2N4U 2N4V 2N4W 2NNT 3HFH 3Q1I 4FQG 7ABF 7ABG 8Q7N 8QO9	2CTR
Enriched GO Terms of Interacting Partners?		MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Spliceosomal Complex RNA Splicing MRNA Processing MRNA Metabolic Process RNA Binding Catalytic Step 2 Spliceosome Spliceosomal Complex Assembly Nucleic Acid Metabolic Process Nuclear Speck Nucleoplasm U2-type Prespliceosome Assembly Nucleus Nucleic Acid Binding U2 SnRNP RNA Metabolic Process Nucleobase-containing Compound Metabolic Process U2-type Spliceosomal Complex U2-type Precatalytic Spliceosome RNA Processing Protein-containing Complex Assembly Protein-containing Complex Organization Protein-RNA Complex Assembly Paraspeckles Cellular Component Assembly MRNA Splice Site Recognition MRNA 3'-splice Site Recognition U2-type Prespliceosome Regulation Of RNA Splicing SCAR Complex Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Nuclear Matrix Regulation Of Gene Expression Negative Regulation Of RNA Metabolic Process Actin Binding Positive Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Negative Regulation Of MRNA Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Actin Polymerization Or Depolymerization Alternative MRNA Splicing, Via Spliceosome U12-type Spliceosomal Complex MRNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process
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