POP1 and WEE2-AS1

Number of citations of the paper that reports this interaction (PubMedID 36123327)
40

Data Source:
BioGRID (unspecified method)

		POP1	WEE2-AS1
Description		POP1 ribonuclease P/MRP subunit	WEE2 antisense RNA 1
Image			No pdb structure
GO Annotations	Cellular Component	Ribonuclease MRP Complex Extracellular Space Nucleus Nucleoplasm Nucleolar Ribonuclease P Complex Nucleolus Multimeric Ribonuclease P Complex	U1 SnRNP
	Molecular Function	RNA Binding Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding	Pre-mRNA 5'-splice Site Binding
	Biological Process	TRNA 5'-leader Removal TRNA Processing TRNA Decay	MRNA 5'-splice Site Recognition
Pathways		tRNA processing in the nucleus
Drugs
Diseases
GWAS		Glucocorticoid receptor gene expression in B-cell precursor acute lymphoblastic leukaemia ( 33002292)
Interacting Genes		10 interacting genes: POP4 POP5 PTEN PYCARD RPP25 RPP30 RPP38 RPP40 USP7 WEE2-AS1	161 interacting genes: AASS ACSL3 ACTG1 AGAP1 AHNAK AJUBA AKAP11 ALB ALKBH4 ANXA2 ARL6IP4 ASPSCR1 ATAD3A BCLAF1 BRAT1 CALML5 CLPB COPB2 COPG1 CSTF1 CTNND1 CTU2 DAXX DDX1 DDX23 DIDO1 DLST DNAAF5 DOHH DPYSL4 DSC1 DSP EEF1A1 EGR2 EIF3A ELL EMD EPM2AIP1 ERAP1 ERH EXOC4 FAM120B FAM83H FLG FLG2 FMR1 FOXK1 FXR1 FXR2 GAB1 GAPDH GBF1 GNL3 GRB10 GSDME GSN GTF3C1 GTPBP1 GTSE1 HARS1 HAX1 HMGA1 HMGCS1 HNRNPA2B1 HNRNPC HNRNPH1 HNRNPH2 HNRNPLL HNRNPM HSP90AA1 HSP90AB1 HSPA6 HSPA8 HSPB1 IFIT1 IGF2BP1 IGF2BP3 KCTD3 KIF20A KIF22 LAMC1 LARP7 LDLR LUC7L2 MAGED2 MAP1A MED23 MINDY3 MOB1A MSH6 MYH9 MYO1C NCKAP1 NDFIP1 NEK9 NISCH NPM1 NUP160 NXF1 PABPC1 PALS2 PARP1 PCMT1 PDCD2L PDXP PIGU PJA2 PLEC POP1 PPL PPM1F PRKAR2A PSMB1 PSMD1 PTK2 QTRT2 RAB5A RAF1 RETREG2 RPL13 RPLP2 RPN2 RPP30 RPRD1B RPS17 RPS2 RPS28 RPS29 RPS8 S100A14 S100A7 SEC13 SERBP1 SHKBP1 SHTN1 SKIC2 SLC25A11 SLC27A3 SNX8 SQSTM1 SRP68 STAT5B TANK THBS1 THRAP3 TIMELESS TMPO TOR1AIP2 TPR TRIM21 TRIM56 TRMT10C TTC28 TUBA1B TUBB3 TUBB4B U2AF1 UBB USP1 XRCC6 YBX1
Entrez ID		10940	285962
HPRD ID		03923	08286
Ensembl ID		ENSG00000104356	ENSG00000228775
Uniprot IDs		Q96F88 Q99575
PDB IDs		6AHR 6AHU
Enriched GO Terms of Interacting Partners?		Ribonuclease MRP Complex Ribonuclease P RNA Binding Multimeric Ribonuclease P Complex Ribonuclease P Activity TRNA 5'-leader Removal TRNA 5'-end Processing Nucleolar Ribonuclease P Complex TRNA Processing TRNA Metabolic Process Ribonuclease P Complex RRNA Processing RRNA Metabolic Process Nucleolus RNA Processing Nucleoplasm Nucleic Acid Metabolic Process RNA Metabolic Process RNA Binding Nucleobase-containing Compound Metabolic Process Negative Regulation Of Synaptic Vesicle Clustering Ribonuclease MRP Activity Myosin I Binding Regulation Of Protein Stability Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Macromolecule Metabolic Process Nucleus Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity NLRP6 Inflammasome Complex Pyrin Domain Binding Positive Regulation Of Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II PML Body Central Nervous System Myelin Maintenance Negative Regulation Of Protein Phosphorylation Rhythmic Synaptic Transmission Symbiont-mediated Disruption Of Host Cell PML Body AIM2 Inflammasome Complex Myeloid Dendritic Cell Activation Involved In Immune Response Negative Regulation Of Phosphorylation Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Pre-mRNA 5'-splice Site Binding Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Phosphatidylinositol Phosphate Phosphatase Activity Regulation Of Synaptic Vesicle Clustering Regulation Of Establishment Of Protein Localization To Telomere NLRP1 Inflammasome Complex Negative Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Protein Metabolic Process	RNA Binding Cytosol Ribonucleoprotein Complex Cytoplasm Nucleus Focal Adhesion Extracellular Exosome Nucleobase-containing Compound Metabolic Process Macromolecule Metabolic Process Nucleic Acid Metabolic Process RNA Metabolic Process Regulation Of Protein Metabolic Process Cytoplasmic Stress Granule MRNA Binding N6-methyladenosine-containing RNA Reader Activity Protein Binding MRNA Processing RNA Transport Nucleolus MRNA Transport Biological_process RNA Processing Nucleic Acid Binding Cellular Response To Heat Translation Regulator Activity Positive Regulation Of Protein Metabolic Process Nucleoplasm Positive Regulation Of Metabolic Process Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Cornified Envelope Positive Regulation Of Macromolecule Metabolic Process MRNA Metabolic Process Positive Regulation Of Biosynthetic Process Response To Heat Regulation Of Translation Regulation Of MRNA Stability CRD-mediated MRNA Stabilization Ficolin-1-rich Granule Lumen MRNA 3'-UTR Binding Nucleobase-containing Compound Transport Regulation Of RNA Stability Negative Regulation Of MRNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Ubiquitin Protein Ligase Binding Structural Molecule Activity Positive Regulation Of Gene Expression RNA Splicing Cadherin Binding Negative Regulation Of MRNA Catabolic Process Regulation Of Plasma Membrane Organization
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