POP1 and RPP30

Number of citations of the paper that reports this interaction (PubMedID 35271311)
106

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology)
HPRD (two hybrid)

		POP1	RPP30
Description		POP1 ribonuclease P/MRP subunit	ribonuclease P/MRP subunit p30
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GO Annotations	Cellular Component	Ribonuclease MRP Complex Extracellular Space Nucleus Nucleoplasm Nucleolar Ribonuclease P Complex Nucleolus Multimeric Ribonuclease P Complex	Ribonuclease MRP Complex Nucleus Nucleoplasm Nucleolar Ribonuclease P Complex Nucleolus Multimeric Ribonuclease P Complex
	Molecular Function	RNA Binding Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding	RNA Binding Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding
	Biological Process	TRNA 5'-leader Removal TRNA Processing TRNA Decay	TRNA 5'-leader Removal RRNA Processing TRNA Processing
Pathways		tRNA processing in the nucleus	tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Glucocorticoid receptor gene expression in B-cell precursor acute lymphoblastic leukaemia ( 33002292)	Economic and political preferences (time) ( 22566634) Metabolite levels ( 23823483)
Interacting Genes		10 interacting genes: POP4 POP5 PTEN PYCARD RPP25 RPP30 RPP38 RPP40 USP7 WEE2-AS1	14 interacting genes: CEBPA HMG20A KHDRBS2 MAST1 POP1 POP4 PTEN RNF32 RPP14 RPP21 RPP38 RPP40 UBC WEE2-AS1
Entrez ID		10940	10556
HPRD ID		03923	09359
Ensembl ID		ENSG00000104356	ENSG00000148688
Uniprot IDs		Q96F88 Q99575	P78346
PDB IDs		6AHR 6AHU	6AHR 6AHU
Enriched GO Terms of Interacting Partners?		Ribonuclease MRP Complex Ribonuclease P RNA Binding Multimeric Ribonuclease P Complex Ribonuclease P Activity TRNA 5'-leader Removal TRNA 5'-end Processing Nucleolar Ribonuclease P Complex TRNA Processing TRNA Metabolic Process Ribonuclease P Complex RRNA Processing RRNA Metabolic Process Nucleolus RNA Processing Nucleoplasm Nucleic Acid Metabolic Process RNA Metabolic Process RNA Binding Nucleobase-containing Compound Metabolic Process Negative Regulation Of Synaptic Vesicle Clustering Ribonuclease MRP Activity Myosin I Binding Regulation Of Protein Stability Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Macromolecule Metabolic Process Nucleus Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity NLRP6 Inflammasome Complex Pyrin Domain Binding Positive Regulation Of Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II PML Body Central Nervous System Myelin Maintenance Negative Regulation Of Protein Phosphorylation Rhythmic Synaptic Transmission Symbiont-mediated Disruption Of Host Cell PML Body AIM2 Inflammasome Complex Myeloid Dendritic Cell Activation Involved In Immune Response Negative Regulation Of Phosphorylation Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Pre-mRNA 5'-splice Site Binding Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Phosphatidylinositol Phosphate Phosphatase Activity Regulation Of Synaptic Vesicle Clustering Regulation Of Establishment Of Protein Localization To Telomere NLRP1 Inflammasome Complex Negative Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Protein Metabolic Process	Ribonuclease P RNA Binding Multimeric Ribonuclease P Complex Ribonuclease P Activity TRNA 5'-leader Removal TRNA 5'-end Processing Nucleolar Ribonuclease P Complex Ribonuclease MRP Complex TRNA Processing Ribonuclease P Complex TRNA Metabolic Process RNA Processing Endoribonuclease Complex Nucleolus RNA Metabolic Process RNA Binding Nucleic Acid Metabolic Process Nucleoplasm Macromolecule Metabolic Process Nucleobase-containing Compound Metabolic Process RRNA Processing RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Negative Regulation Of Synaptic Vesicle Clustering Ribonuclease MRP Activity RRNA Metabolic Process Response To Vitamin B2 C/EBP Complex Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity
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