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EHMT2 and CHCHD2
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
EHMT2
CHCHD2
Gene Name
euchromatic histone-lysine N-methyltransferase 2
coiled-coil-helix-coiled-coil-helix domain containing 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nuclear Chromatin
Nucleus
Nucleoplasm
Intracellular Membrane-bounded Organelle
Intermediate Filament Cytoskeleton
Mitochondrion
Molecular Function
P53 Binding
Protein Binding
Zinc Ion Binding
Protein-lysine N-methyltransferase Activity
Histone-lysine N-methyltransferase Activity
Histone Methyltransferase Activity (H3-K9 Specific)
Histone Methyltransferase Activity (H3-K27 Specific)
C2H2 Zinc Finger Domain Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of DNA Replication
DNA Methylation
Chromatin Organization
Histone Methylation
Peptidyl-lysine Dimethylation
Histone Lysine Methylation
Histone H3-K9 Methylation
Histone H3-K27 Methylation
Pathways
Chromatin modifying enzymes
Chromatin organization
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
RNA Polymerase I Transcription
RNA Polymerase I Transcription Initiation
PKMTs methylate histone lysines
RNA Polymerase I Promoter Clearance
Cellular Senescence
Senescence-Associated Secretory Phenotype (SASP)
Drugs
Diseases
GWAS
Chronic hepatitis B infection (
23760081
)
Economic and political preferences (environmentalism) (
22566634
)
Epstein-Barr virus immune response (EBNA-1) (
23326239
)
Protein-Protein Interactions
42 interactors:
C10orf12
CACNA1A
CBX1
CCDC33
CHCHD2
CUX1
DNMT3A
E4F1
ESR1
FAM161A
H3F3B
HGS
HIST1H1A
HIST1H1B
HIST1H3A
HIST2H3A
HIST2H3C
HIST3H3
ITGB5
KLF12
KLF3
KLF6
LIMS1
LMO2
LNX1
MX2
NAA10
NAPRT
PLOD3
PRRC2B
PSMA1
RD3
RELB
RERE
RUVBL2
THAP7
TP53
WIZ
XAGE2
ZBTB38
ZNF512B
ZNF785
12 interactors:
ADAMTSL4
EHMT2
GOLGA2
IKZF3
INCA1
KRT31
KRT40
LHX4
REL
TCF4
TRIM54
UBC
Entrez ID
10919
51142
HPRD ID
06854
09879
Ensembl ID
ENSG00000204371
ENSG00000106153
Uniprot IDs
A2ABF8
A2ABF9
Q96KQ7
Q9Y6H1
PDB IDs
2O8J
3DM1
3K5K
3RJW
Enriched GO Terms of Interacting Partners
?
DNA Methylation On Cytosine
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Chromatin Silencing
Gene Expression
Regulation Of Transcription, DNA-templated
Negative Regulation Of Cellular Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Chromatin Silencing At RDNA
DNA Methylation
Cellular Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Nitrogen Compound Metabolic Process
Negative Regulation Of Gene Expression, Epigenetic
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
DNA Conformation Change
Regulation Of Metabolic Process
Chromosome Organization
DNA Modification
DNA Packaging
Transcription, DNA-templated
Gene Silencing
RNA Biosynthetic Process
Chromatin Organization
Chromatin Assembly
Chromatin Assembly Or Disassembly
Positive Regulation Of Gene Expression
Cellular Component Assembly
Regulation Of Gene Expression, Epigenetic
DNA Metabolic Process
Establishment Of Protein Localization To Chromatin
RNA Metabolic Process
Nucleosome Assembly
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Nucleosome Organization
Cellular Response To Organic Substance
Positive Regulation Of Cellular Biosynthetic Process
Protein-DNA Complex Assembly
Organelle Organization
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Transcription, DNA-templated
Regulation Of Cell Death
Regulation Of Apoptotic Process
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Cell Death
Negative Regulation Of Transcription From RNA Polymerase II Promoter
I-kappaB Kinase/NF-kappaB Signaling
Glycogen Metabolic Process
Polysaccharide Metabolic Process
Negative Regulation Of Cell Death
Regulation Of Transcription From RNA Polymerase II Promoter
Medial Motor Column Neuron Differentiation
Catenin Import Into Nucleus
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Negative Regulation Of Cell Cycle
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Negative Regulation Of Cellular Metabolic Process
Energy Reserve Metabolic Process
Maintenance Of DNA Repeat Elements
DNA Methylation On Cytosine Within A CG Sequence
Positive Regulation Of Signal Transduction
Glucose Metabolic Process
Regulation Of Protein Binding
Negative Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Gene Expression
Transcription, DNA-templated
Negative Regulation Of Biosynthetic Process
Transcription Initiation From RNA Polymerase II Promoter
Cell Cycle
Negative Regulation Of Type B Pancreatic Cell Apoptotic Process
Embryonic Hindgut Morphogenesis
Cellular Macromolecule Biosynthetic Process
RNA Biosynthetic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Macromolecule Biosynthetic Process
Embryonic Genitalia Morphogenesis
Regulation Of Cellular Response To Growth Factor Stimulus
Somatic Motor Neuron Differentiation
Myoblast Fate Commitment
Negative Regulation Of Wnt Signaling Pathway
Developmental Process Involved In Reproduction
Hexose Metabolic Process
Secretory Granule Localization
Histone H3-K27 Methylation
DNA-templated Transcription, Initiation
Tagcloud
?
availability
biosensor
bix01294
chaetocin
codc
enables
expedite
fluc2
g4s
h3
h4
imaging
k9
live
lysine
mark
methylation
methylations
methyltransferase
monitor
nude
pace
preclinical
replacement
reveals
sensor
suv39h1
treating
utility
Tagcloud (Difference)
?
availability
biosensor
bix01294
chaetocin
codc
enables
expedite
fluc2
g4s
h3
h4
imaging
k9
live
lysine
mark
methylation
methylations
methyltransferase
monitor
nude
pace
preclinical
replacement
reveals
sensor
suv39h1
treating
utility
Tagcloud (Intersection)
?