YIF1A and PTGES

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		YIF1A	PTGES
Description		Yip1 interacting factor homolog A, membrane trafficking protein	prostaglandin E synthase
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Membrane COPII-coated ER To Golgi Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Nuclear Envelope Lumen Cytoplasm Endoplasmic Reticulum Membrane Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Glutathione Transferase Activity Glutathione Peroxidase Activity Prostaglandin-D Synthase Activity Protein Binding Oxidoreductase Activity Transferase Activity Isomerase Activity Glutathione Binding Prostaglandin-E Synthase Activity
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport	Prostaglandin Biosynthetic Process Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Prostaglandin Metabolic Process Signal Transduction Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Sensory Perception Of Pain Regulation Of Fever Generation Positive Regulation Of Prostaglandin Secretion Regulation Of Inflammatory Response Cellular Oxidant Detoxification
Pathways		XBP1(S) activates chaperone genes	Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972 31043756) Glucose homeostasis traits ( 25524916)	Asthma ( 27611488) Pars orbitalis volume ( 31530798) Type 1 diabetes (age at diagnosis) ( 33179336)
Interacting Genes		71 interacting genes: APOA5 AQP6 ARLN BNIP2 CD79A CDK2AP2 CERS2 CNRIP1 CST6 EBP ELOVL4 ERGIC3 FAM210B FARS2 FCER1G FFAR2 GAS7 GJA8 GPR37 GPR42 GPX8 JOSD2 LNPK LSS MARCHF5 MGST3 MIEF2 MLLT1 MMGT1 MSMO1 MTERF3 MYG1 NDRG4 PLEKHF2 PPIF PTGES PTPN9 RBFA REEP2 REEP4 RIC3 RNF144A SCN3B SCN4B SDCBP SEC23IP SLC10A1 SLC34A1 SLC35H1 SNX10 SNX11 SNX2 SYTL2 SYTL5 TIMMDC1 TMEM139 TMEM14B TMEM17 TMEM225B TMEM248 TMEM31 TMX2 VKORC1 VMA21 WDFY2 YIPF4 YIPF5 ZDHHC16 ZDHHC17 ZFYVE21 ZFYVE27	18 interacting genes: ARLN BET1 EHHADH GIMAP1 GIMAP5 PLP2 PTGER1 PTGER2 SEC22A SERP2 SMCO4 TMEM19 TMEM222 TMEM65 VAMP3 VAMP4 VAPB YIF1A
Entrez ID		10897	9536
HPRD ID		06755	05528
Ensembl ID		ENSG00000174851	ENSG00000148344
Uniprot IDs		A6NGW1 A8K509 O95070	O14684
PDB IDs			3DWW 4AL0 4AL1 4BPM 4WAB 4YK5 4YL0 4YL1 4YL3 5BQG 5BQH 5BQI 5K0I 5T36 5T37 5TL9 6VL4 8PYV
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Membrane Membrane Endoplasmic Reticulum Protein Binding Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Glutathione Peroxidase Activity Voltage-gated Sodium Channel Activity Involved In Cardiac Muscle Cell Action Potential Regulation Of Mast Cell Apoptotic Process Endoplasmic Reticulum Organization	Golgi Vesicle Transport Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum To Golgi Vesicle-mediated Transport SNAP Receptor Activity Prostaglandin E Receptor Activity SNARE Complex Endoplasmic Reticulum SNARE Complex Assembly Transport Vesicle Vesicle Organization Organelle Fusion Response To Prostaglandin E Membrane Fusion Golgi To Plasma Membrane Protein Transport Vesicle-mediated Transport Intracellular Transport Establishment Of Protein Localization To Plasma Membrane Long-chain (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity Intramolecular Oxidoreductase Activity, Transposing C=C Bonds Presynaptic Endosome Membrane Golgi To Plasma Membrane Transport Negative Regulation By Virus Of Viral Protein Levels In Host Cell Endoplasmic Reticulum Unfolded Protein Response Clathrin-coated Endocytic Vesicle Membrane Cellular Response To Type II Interferon Synaptic Vesicle To Endosome Fusion FFAT Motif Binding Organelle Localization By Membrane Tethering Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Delta(3)-delta(2)-enoyl-CoA Isomerase Activity Prostaglandin Receptor Activity Cellular Localization Protein Transport Golgi Membrane Phagocytic Vesicle Establishment Of Localization In Cell Membrane Organization Response To Unfolded Protein Membrane Docking Phospholipase C-activating G Protein-coupled Glutamate Receptor Signaling Pathway Response To Type II Interferon Post-Golgi Vesicle-mediated Transport COPII-coated Vesicle Budding Endoplasmic Reticulum-plasma Membrane Tethering Organelle Membrane Fusion Vesicle Fusion (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity Trans-Golgi Network Membrane Host-mediated Perturbation Of Viral RNA Genome Replication
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