YIF1A and SLC34A1

Number of citations of the paper that reports this interaction (PMID 11099500)
37

Data Source:
HPRD (two hybrid)

		YIF1A	SLC34A1
Gene Name		Yip1 interacting factor homolog A (S. cerevisiae)	solute carrier family 34 (type II sodium/phosphate cotransporter), member 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Microtubule Organizing Center Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Endosome Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Basolateral Plasma Membrane Apical Plasma Membrane Brush Border Membrane Membrane-bounded Vesicle Membrane Raft Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Protein Binding Symporter Activity Sodium-dependent Phosphate Transmembrane Transporter Activity PDZ Domain Binding Protein Complex Binding Protein Homodimerization Activity
	Biological Process	Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Protein Transport Vesicle-mediated Transport Endoplasmic Reticulum Unfolded Protein Response Cellular Protein Metabolic Process	Ossification Kidney Development Ion Transport Sodium Ion Transport Phosphate Ion Transport Glycoprotein Metabolic Process Response To Lead Ion Response To Magnesium Ion Response To Estradiol Response To Vitamin A Response To Potassium Ion Indole Metabolic Process Response To Drug Sodium-dependent Phosphate Transport Positive Regulation Of Membrane Potential Response To Cadmium Ion Response To Mercury Ion Bone Remodeling Protein Homooligomerization Phosphate Ion Homeostasis Transmembrane Transport Response To Growth Hormone Cellular Response To Metal Ion Cellular Response To Parathyroid Hormone Stimulus Tricarboxylic Acid Metabolic Process Cellular Response To Staurosporine Response To Thyroid Hormone Dentinogenesis Gentamycin Metabolic Process Arsenate Ion Transmembrane Transport Positive Regulation Of Sodium-dependent Phosphate Transport Positive Regulation Of Phosphate Transmembrane Transport
Pathways		IRE1alpha activates chaperones XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)	Sodium-coupled phosphate cotransporters Type II Na+/Pi cotransporters Transport of inorganic cations/anions and amino acids/oligopeptides SLC-mediated transmembrane transport
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)	Activated partial thromboplastin time ( 22703881) Chronic kidney disease ( 20383146) Nephrolithiasis ( 22396660)
Protein-Protein Interactions		5 interactors: CDK2AP2 SLC34A1 VKORC1 YIPF5 ZDHHC17	10 interactors: BSPRY FHL2 HPCAL1 HSP90AA1 HSP90AB1 MAST2 PEX19 SLC9A3R1 SLC9A3R2 YIF1A
Entrez ID		10897	6569
HPRD ID		06755	08918
Ensembl ID		ENSG00000174851	ENSG00000131183
Uniprot IDs		A6NGW1 A8K509 O95070	Q06495 Q7Z725 Q86VN6
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Sodium-dependent Phosphate Transport Indole Metabolic Process Positive Regulation Of Phosphate Transmembrane Transport Gentamycin Metabolic Process Arsenate Ion Transmembrane Transport Cellular Response To Staurosporine Regulation Of Sodium-dependent Phosphate Transport Dentinogenesis Regulation Of Phosphate Transport Vitamin K Metabolic Process Sodium-dependent Phosphate Transport Cellular Response To Parathyroid Hormone Stimulus Response To Potassium Ion Response To Parathyroid Hormone Peptidyl-glutamic Acid Carboxylation Phosphate Ion Homeostasis Regulation Of ER To Golgi Vesicle-mediated Transport Phosphate Ion Transmembrane Transport Response To Thyroid Hormone Glycoside Metabolic Process Response To Magnesium Ion Lipoprotein Transport Cellular Response To Ammonium Ion Magnesium Ion Transport Phosphate Ion Transport Response To Mercury Ion Response To Vitamin A Protein Palmitoylation Response To Lead Ion Quinone Metabolic Process Drug Metabolic Process Cellular Response To Alkaloid Response To Growth Hormone Positive Regulation Of Membrane Potential Metal Ion Transport Anion Homeostasis Tricarboxylic Acid Metabolic Process Response To Cadmium Ion Bone Remodeling Positive Regulation Of Ion Transmembrane Transport Cellular Ketone Metabolic Process Cation Transport	Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Response To Unfolded Protein Regulation Of Cellular Response To Heat Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Protein Folding Intracellular Protein Transmembrane Transport Regulation Of Nitric Oxide Biosynthetic Process Protein Transmembrane Transport Regulation Of Reactive Oxygen Species Biosynthetic Process Cellular Response To Heat Renal Phosphate Ion Absorption Negative Regulation Of Lipid Binding Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Phosphatidylinositol 3-kinase Signaling Negative Regulation Of Sodium:proton Antiporter Activity Glutathione Transport Response To Heat Atrial Cardiac Muscle Cell Development Peroxisome Membrane Biogenesis Protein Import Into Mitochondrial Outer Membrane Regulation Of Reactive Oxygen Species Metabolic Process Protein Import Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Renal Sodium Ion Transport Cellular Phosphate Ion Homeostasis Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Response To Temperature Stimulus Negative Regulation Of Sodium Ion Transmembrane Transport Regulation Of Protein Kinase Activity Intracellular Receptor Signaling Pathway Protein Import Into Peroxisome Membrane Chaperone-mediated Protein Transport Phospholipase C-activating Dopamine Receptor Signaling Pathway Peroxisomal Membrane Transport Regulation Of Kinase Activity Establishment Of Protein Localization To Membrane Bile Acid Secretion Peroxisome Fission Oligopeptide Transport Regulation Of Binding Phagocytosis Positive Regulation Of Protein Import Into Nucleus, Translocation Negative Regulation Of Sodium Ion Transport Renal Absorption Regulation Of Proton Transport Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway
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