YIF1A and CST6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		YIF1A	CST6
Description		Yip1 interacting factor homolog A, membrane trafficking protein	cystatin E/M
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Membrane COPII-coated ER To Golgi Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Cornified Envelope Extracellular Region Extracellular Exosome
	Molecular Function	Protein Binding	Cysteine-type Endopeptidase Inhibitor Activity Protein Binding Peptidase Inhibitor Activity
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport	Epidermis Development Anatomical Structure Morphogenesis
Pathways		XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972 31043756) Glucose homeostasis traits ( 25524916)	A body shape index ( 34021172) Acne (severe) ( 24927181) Bipolar disorder ( 31043756) Blood protein levels ( 30072576) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Height ( 31562340) Serum uric acid levels ( 32514006) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		71 interacting genes: APOA5 AQP6 ARLN BNIP2 CD79A CDK2AP2 CERS2 CNRIP1 CST6 EBP ELOVL4 ERGIC3 FAM210B FARS2 FCER1G FFAR2 GAS7 GJA8 GPR37 GPR42 GPX8 JOSD2 LNPK LSS MARCHF5 MGST3 MIEF2 MLLT1 MMGT1 MSMO1 MTERF3 MYG1 NDRG4 PLEKHF2 PPIF PTGES PTPN9 RBFA REEP2 REEP4 RIC3 RNF144A SCN3B SCN4B SDCBP SEC23IP SLC10A1 SLC34A1 SLC35H1 SNX10 SNX11 SNX2 SYTL2 SYTL5 TIMMDC1 TMEM139 TMEM14B TMEM17 TMEM225B TMEM248 TMEM31 TMX2 VKORC1 VMA21 WDFY2 YIPF4 YIPF5 ZDHHC16 ZDHHC17 ZFYVE21 ZFYVE27	7 interacting genes: BCAR3 GSK3B NOTCH2 PALB2 RAD51 TGFB1 YIF1A
Entrez ID		10897	1474
HPRD ID		06755	03535
Ensembl ID		ENSG00000174851	ENSG00000175315
Uniprot IDs		A6NGW1 A8K509 O95070	Q15828
PDB IDs			4N6L 4N6M 4N6N 4N6O 6FK0
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Membrane Membrane Endoplasmic Reticulum Protein Binding Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Glutathione Peroxidase Activity Voltage-gated Sodium Channel Activity Involved In Cardiac Muscle Cell Action Potential Regulation Of Mast Cell Apoptotic Process Endoplasmic Reticulum Organization	Enzyme-linked Receptor Protein Signaling Pathway NF-kappaB Binding Myeloid Dendritic Cell Activation Gland Morphogenesis Myeloid Dendritic Cell Differentiation Positive Regulation Of Smooth Muscle Cell Differentiation Positive Regulation Of Nucleocytoplasmic Transport Regulation Of Microtubule Anchoring At Centrosome Regulation Of Intracellular Signal Transduction Enzyme Binding Developmental Growth Regulation Of MiRNA Transcription Dendritic Cell Differentiation Positive Regulation Of MiRNA Metabolic Process Regulation Of Smooth Muscle Cell Differentiation Positive Regulation Of MiRNA Transcription Kidney Epithelium Development Positive Regulation Of Myeloid Leukocyte Differentiation Heart Valve Morphogenesis Positive Regulation Of Muscle Cell Differentiation Response To Xenobiotic Stimulus Response To Glucoside Cellular Response To Ionizing Radiation Branch Elongation Involved In Mammary Gland Duct Branching Positive Regulation Of Microglia Differentiation Cellular Response To Acetaldehyde Superior Temporal Gyrus Development Negative Regulation Of Type B Pancreatic Cell Development Canonical Wnt Signaling Pathway Negative Regulation Of Mesenchymal Stem Cell Differentiation Positive Regulation Of Intracellular Signal Transduction Negative Regulation Of Glycogen (starch) Synthase Activity Epithelial To Mesenchymal Transition Positive Regulation Of Intracellular Protein Transport Mesenchymal Cell Differentiation Insulin Receptor Signaling Pathway Tissue Remodeling Cholangiocyte Proliferation Multicellular Organism Growth Regulation Of MiRNA Metabolic Process Positive Regulation Of MAPK Cascade Positive Regulation Of Myeloid Cell Differentiation Intrahepatic Bile Duct Development Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Liver Development Liver Morphogenesis Mitotic Recombination-dependent Replication Fork Processing DNA Strand Exchange Activity Presynaptic Intermediate Filament Cytoskeleton Positive Regulation Of Primary MiRNA Processing
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