YIF1A and RIC3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		YIF1A	RIC3
Description		Yip1 interacting factor homolog A, membrane trafficking protein	RIC3 acetylcholine receptor chaperone
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Membrane COPII-coated ER To Golgi Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane Neuron Projection Neuronal Cell Body Intracellular Membrane-bounded Organelle Synapse
	Molecular Function	Protein Binding	Protein Binding Acetylcholine Receptor Binding Protein Folding Chaperone
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport	Protein Folding Positive Regulation Of Cytosolic Calcium Ion Concentration Synaptic Transmission, Cholinergic Protein Localization To Cell Surface Protein-containing Complex Assembly Positive Regulation Of Protein Localization To Cell Surface
Pathways		XBP1(S) activates chaperone genes
Drugs			Theophylline
Diseases
GWAS		Bipolar disorder ( 21926972 31043756) Glucose homeostasis traits ( 25524916)	Blood protein levels ( 30072576) Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Malaria ( 31844061)
Interacting Genes		71 interacting genes: APOA5 AQP6 ARLN BNIP2 CD79A CDK2AP2 CERS2 CNRIP1 CST6 EBP ELOVL4 ERGIC3 FAM210B FARS2 FCER1G FFAR2 GAS7 GJA8 GPR37 GPR42 GPX8 JOSD2 LNPK LSS MARCHF5 MGST3 MIEF2 MLLT1 MMGT1 MSMO1 MTERF3 MYG1 NDRG4 PLEKHF2 PPIF PTGES PTPN9 RBFA REEP2 REEP4 RIC3 RNF144A SCN3B SCN4B SDCBP SEC23IP SLC10A1 SLC34A1 SLC35H1 SNX10 SNX11 SNX2 SYTL2 SYTL5 TIMMDC1 TMEM139 TMEM14B TMEM17 TMEM225B TMEM248 TMEM31 TMX2 VKORC1 VMA21 WDFY2 YIPF4 YIPF5 ZDHHC16 ZDHHC17 ZFYVE21 ZFYVE27	16 interacting genes: BCL2L1 CACNA1C CLN6 FA2H FATE1 GOSR2 NINJ2 PRB1 STX12 STX7 TMBIM1 TMEFF2 TMEM11 TMEM86A TRAF3IP3 YIF1A
Entrez ID		10897	79608
HPRD ID		06755	17974
Ensembl ID		ENSG00000174851	ENSG00000166405
Uniprot IDs		A6NGW1 A8K509 O95070	A0A0S2Z607 A0A0S2Z6D3 B7Z3Z0 Q7Z5B4
PDB IDs
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Membrane Membrane Endoplasmic Reticulum Protein Binding Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Glutathione Peroxidase Activity Voltage-gated Sodium Channel Activity Involved In Cardiac Muscle Cell Action Potential Regulation Of Mast Cell Apoptotic Process Endoplasmic Reticulum Organization	Membrane SNARE Complex SNAP Receptor Activity Membrane Organization Endoplasmic Reticulum SNARE Binding Vesicle Fusion Organelle Membrane Fusion Regulation Of Protein Localization To Plasma Membrane Organelle Fusion Golgi Membrane Endoplasmic Reticulum Membrane Regulation Of Protein Localization To Cell Periphery Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Protein Localization To Plasma Membrane Membrane Fusion Regulation Of Protein Localization To Membrane Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Apoptotic Process In Bone Marrow Cell Mitochondrial Outer Membrane Negative Regulation Of Integrin Biosynthetic Process 4-hydroxysphinganine Ceramide Fatty Acyl 2-hydroxylase Activity Free Fatty Acid 2-hydroxylase Activity Fatty Acid 2-hydroxylase Activity Glycosphingolipid Metabolic Process Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Endomembrane System Vesicle Docking Negative Regulation Of Fas Signaling Pathway Sebaceous Gland Cell Differentiation Glucosylceramide Biosynthetic Process Regulation Of Sebum Secreting Cell Proliferation Regulation Of Acinar Cell Proliferation Alkenylglycerophosphocholine Hydrolase Activity Dendritic Cell Proliferation Dendritic Cell Apoptotic Process Membrane Depolarization During Atrial Cardiac Muscle Cell Action Potential Calcium Channel Activity Voltage-gated Calcium Channel Activity Involved In AV Node Cell Action Potential Voltage-gated Calcium Channel Activity Involved In Cardiac Muscle Cell Action Potential Vesicle Organization Tertiary Granule Organelle Localization By Membrane Tethering Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Central Nervous System Myelin Maintenance Membrane Docking Vesicle-mediated Transport Membrane Destabilizing Activity Positive Regulation Of Receptor Localization To Synapse Glycolipid Metabolic Process
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