PTGES

Gene Name		prostaglandin E synthase
Image
Gene Ontology Annotations	Cellular Component	Nuclear Envelope Lumen Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Glutathione Binding Prostaglandin-E Synthase Activity
	Biological Process	Prostaglandin Biosynthetic Process Acute Inflammatory Response Chronic Inflammatory Response Prostaglandin Metabolic Process Signal Transduction Negative Regulation Of Cell Proliferation Response To Organic Cyclic Compound Arachidonic Acid Metabolic Process Cyclooxygenase Pathway Response To Lipopolysaccharide Response To Retinoic Acid Response To Cytokine Small Molecule Metabolic Process Response To Calcium Ion
Pathways		Arachidonic acid metabolism Metabolism of lipids and lipoproteins Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: PTGER1 PTGER2
Entrez ID		9536
HPRD ID		05528
Ensembl ID		ENSG00000148344
Uniprot IDs		O14684
PDB IDs		3DWW 4AL0 4AL1
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Eosinophil Extravasation Negative Regulation Of Integrin Activation Negative Regulation Of Eosinophil Migration Response To Lipopolysaccharide Response To Molecule Of Bacterial Origin Response To Bacterium Regulation Of Integrin Activation Response To Other Organism Response To Biotic Stimulus Cellular Response To Prostaglandin E Stimulus Response To Lipid ERK1 And ERK2 Cascade Response To Prostaglandin E Cellular Response To Prostaglandin Stimulus Negative Regulation Of Leukocyte Migration T-helper Cell Differentiation G-protein Coupled Receptor Signaling Pathway Negative Regulation Of Cytokine Secretion CD4-positive, Alpha-beta T Cell Differentiation CD4-positive, Alpha-beta T Cell Activation Cellular Response To Fatty Acid Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Alpha-beta T Cell Differentiation Regulation Of Stress Fiber Assembly Alpha-beta T Cell Activation T Cell Activation Involved In Immune Response Response To Fatty Acid Response To External Stimulus Cellular Response To Mechanical Stimulus JNK Cascade Positive Regulation Of Cytokine Secretion Positive Regulation Of Inflammatory Response Negative Regulation Of Protein Secretion Negative Regulation Of Inflammatory Response Regulation Of Leukocyte Migration Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Negative Regulation Of Protein Complex Assembly Regulation Of Cytokine Secretion Response To Organic Substance G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger T Cell Differentiation Leukocyte Activation Involved In Immune Response Negative Regulation Of Secretion By Cell Cellular Response To Acid Chemical Negative Regulation Of Secretion Negative Regulation Of Protein Transport Positive Regulation Of Protein Secretion Negative Regulation Of Cell Migration
Tagcloud ?		acsf artificial avp balance cannulas cart cerebrospinal cerebroventricular circuits creb1 gabrd gip gipr gut hypothalami hypothalamic hypothalamus incretin insulinotrophic mapk1 microl neurocircuitry npy originally oxt polypeptide quantitatively taqman th