YIF1A and SNX10

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		YIF1A	SNX10
Description		Yip1 interacting factor homolog A, membrane trafficking protein	sorting nexin 10
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Membrane COPII-coated ER To Golgi Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Nucleus Cytoplasm Endosome Endoplasmic Reticulum Centrosome Cytoskeleton Endosome Membrane Membrane Secretory Granule Extrinsic Component Of Endosome Membrane Apical Cytoplasm
	Molecular Function	Protein Binding	Protein Binding 1-phosphatidylinositol Binding Lipid Binding Phosphatidylinositol Binding ATPase Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport	Gastric Acid Secretion Intracellular Protein Transport Endocytosis Endosome Organization Protein Transport Vesicle Organization Cellular Homeostasis Cell Projection Organization Osteoclast Differentiation Bone Mineralization Involved In Bone Maturation Tooth Eruption Bone Resorption Bone Remodeling Establishment Of Localization In Cell Calcium Ion Homeostasis Cilium Assembly Protein Localization To Cilium Protein Localization To Centrosome Ruffle Assembly Cellular Response To Leukemia Inhibitory Factor
Pathways		XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972 31043756) Glucose homeostasis traits ( 25524916)	A body shape index ( 34021172) Dental caries (decayed, missing and filled teeth) ( 31533690) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Mean reticulocyte volume ( 32888494) Metabolic syndrome ( 31589552) Metabolite levels ( 23823483) Triglyceride levels ( 32203549) Vaginal microbiome composition (G. vaginalis) ( 32723796) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 26426971 34021172) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412)
Interacting Genes		71 interacting genes: APOA5 AQP6 ARLN BNIP2 CD79A CDK2AP2 CERS2 CNRIP1 CST6 EBP ELOVL4 ERGIC3 FAM210B FARS2 FCER1G FFAR2 GAS7 GJA8 GPR37 GPR42 GPX8 JOSD2 LNPK LSS MARCHF5 MGST3 MIEF2 MLLT1 MMGT1 MSMO1 MTERF3 MYG1 NDRG4 PLEKHF2 PPIF PTGES PTPN9 RBFA REEP2 REEP4 RIC3 RNF144A SCN3B SCN4B SDCBP SEC23IP SLC10A1 SLC34A1 SLC35H1 SNX10 SNX11 SNX2 SYTL2 SYTL5 TIMMDC1 TMEM139 TMEM14B TMEM17 TMEM225B TMEM248 TMEM31 TMX2 VKORC1 VMA21 WDFY2 YIPF4 YIPF5 ZDHHC16 ZDHHC17 ZFYVE21 ZFYVE27	3 interacting genes: ARL6IP1 RABAC1 YIF1A
Entrez ID		10897	29887
HPRD ID		06755	15409
Ensembl ID		ENSG00000174851	ENSG00000086300
Uniprot IDs		A6NGW1 A8K509 O95070	B4DJM0 G5E9H5 Q8N5Z3 Q9Y5X0
PDB IDs			4ON3 4PZG 6KOK
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Membrane Membrane Endoplasmic Reticulum Protein Binding Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Glutathione Peroxidase Activity Voltage-gated Sodium Channel Activity Involved In Cardiac Muscle Cell Action Potential Regulation Of Mast Cell Apoptotic Process Endoplasmic Reticulum Organization	Sec61 Translocon Complex Endoplasmic Reticulum Tubular Network Membrane Organization Positive Regulation Of L-glutamate Import Across Plasma Membrane Regulation Of Endoplasmic Reticulum Tubular Network Organization Regulation Of L-glutamate Import Across Plasma Membrane Endoplasmic Reticulum Tubular Network Formation Proline-rich Region Binding Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Membrane Organization Endoplasmic Reticulum Tubular Network Organization Positive Regulation Of Amino Acid Transport Cotranslational Protein Targeting To Membrane GTPase Binding COPII-coated ER To Golgi Transport Vesicle Endoplasmic Reticulum Membrane Endoplasmic Reticulum Organization Endoplasmic Reticulum-Golgi Intermediate Compartment Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Protein Targeting To Membrane Regulation Of Amine Transport
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