PILRA and FCAR

Number of citations of the paper that reports this interaction (PMID 15085135)
144

Data Source:
HPRD (in vitro)

		PILRA	FCAR
Gene Name		paired immunoglobin-like type 2 receptor alpha	Fc fragment of IgA, receptor for
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Extracellular Vesicular Exosome	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding	IgA Binding
	Biological Process	Signal Transduction Viral Process	Immune Response
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: DNPH1 FCAR PTPN11 PTPN6 SORBS1	6 interactors: CD79A FCGR1A LYN OSCAR PILRA PPP2CA
Entrez ID		29992	2204
HPRD ID		05631	00914
Ensembl ID		ENSG00000085514	ENSG00000186431
Uniprot IDs		C9JJ79 Q9UKJ1	P24071
PDB IDs			1OVZ 1OW0 1UCT
Enriched GO Terms of Interacting Partners?		Abortive Mitotic Cell Cycle Megakaryocyte Development Platelet Formation Platelet Morphogenesis Regulation Of Interferon-gamma-mediated Signaling Pathway Regulation Of Response To Interferon-gamma Megakaryocyte Differentiation Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Regulation Of Cell Adhesion Mediated By Integrin Regulation Of Type I Interferon-mediated Signaling Pathway Positive Regulation Of Glucose Import Positive Regulation Of Glucose Transport Response To Peptide Hormone Regulation Of Glucose Import Cellular Response To Organonitrogen Compound Response To Peptide T Cell Costimulation Cellular Response To Hormone Stimulus Regulation Of Cytokine-mediated Signaling Pathway Regulation Of Glucose Transport Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Negative Regulation Of Cortisol Secretion Negative Regulation Of Growth Hormone Secretion Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Type I Interferon Interferon-gamma-mediated Signaling Pathway Cellular Response To Interferon-gamma Insulin Receptor Signaling Pathway Hematopoietic Progenitor Cell Differentiation Response To Organonitrogen Compound Deoxyribonucleoside Monophosphate Catabolic Process Response To Interferon-gamma Enzyme Linked Receptor Protein Signaling Pathway Peptidyl-tyrosine Dephosphorylation Negative Regulation Of Glucocorticoid Secretion Response To Hormone Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Cell Adhesion Positive Regulation Of T Cell Activation Regulation Of Cellular Localization Cellular Response To Insulin Stimulus Positive Regulation Of Homotypic Cell-cell Adhesion Leukocyte Migration Bone Development Negative Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of Cell-cell Adhesion Regulation Of Innate Immune Response Myeloid Cell Differentiation	Immune Response-activating Cell Surface Receptor Signaling Pathway B Cell Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Negative Regulation Of MAP Kinase Activity Regulation Of JAK-STAT Cascade Positive Regulation Of Immune Response Positive Regulation Of Oligodendrocyte Progenitor Proliferation Negative Regulation Of Mast Cell Proliferation Negative Regulation Of Protein Serine/threonine Kinase Activity Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Negative Regulation Of MAPK Cascade Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Immune Response Positive Regulation Of Immune System Process Signal Transduction Tolerance Induction To Self Antigen Fc Receptor Mediated Inhibitory Signaling Pathway Positive Regulation Of Dendritic Cell Apoptotic Process Regulation Of Peptidyl-tyrosine Phosphorylation Signaling Negative Regulation Of Protein Kinase Activity Cell Communication Negative Regulation Of Kinase Activity Negative Regulation Of Toll-like Receptor 2 Signaling Pathway Negative Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Immune Response-inhibiting Cell Surface Receptor Signaling Pathway Immune Response-inhibiting Signal Transduction Phagocytosis Fc Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Regulation Of MAP Kinase Activity Regulation Of Immune System Process Negative Regulation Of Toll-like Receptor 4 Signaling Pathway Tolerance Induction Positive Regulation Of Mast Cell Proliferation Negative Regulation Of Transferase Activity Positive Regulation Of B Cell Receptor Signaling Pathway Negative Regulation Of Protein Phosphorylation Cellular Response To Stimulus Leukocyte Differentiation Regulation Of Oligodendrocyte Progenitor Proliferation Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Mitotic Nuclear Envelope Reassembly Protein Heterotrimerization Histamine Secretion By Mast Cell Nuclear Envelope Reassembly
Tagcloud ?			anca antineutrophil assembled cd11b confocal degranulation engagement extracellcular fcgr3b fcr fcrs genetics granulomatosis haplotype iga igg illumina mucosal multicenter na1 na2 neutrophil polyangiitis pyrosequencing tagging taqman unappreciated vasculitis wegener
Tagcloud (Difference) ?			anca antineutrophil assembled cd11b confocal degranulation engagement extracellcular fcgr3b fcr fcrs genetics granulomatosis haplotype iga igg illumina mucosal multicenter na1 na2 neutrophil polyangiitis pyrosequencing tagging taqman unappreciated vasculitis wegener
Tagcloud (Intersection) ?