MIEF2 and RABAC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		MIEF2	RABAC1
Description		mitochondrial elongation factor 2	Rab acceptor 1
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Peroxisome Membrane	Cytoplasm Golgi Apparatus Plasma Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Synapse Presynapse Glutamatergic Synapse
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding GTPase Binding Proline-rich Region Binding
	Biological Process	Mitochondrion Organization Mitochondrial Fusion Regulation Of Mitochondrion Organization Positive Regulation Of Mitochondrial Fission Positive Regulation Of Protein Targeting To Membrane
Pathways
Drugs
Diseases
GWAS		Change in neurofilament light levels ( 31295725)	Brain morphology (MOSTest) ( 32665545) Left-handedness ( 32989287)
Interacting Genes		30 interacting genes: AGTRAP ARFIP2 ARL6IP1 ATP5PF CIDEA DNM1L FAM114A2 FAM25A FAM25C FAM25G FKBP7 GSG1 HSD17B13 LIME1 MDK NCALD NCS1 PRB2 PSMF1 RABAC1 REEP6 RHBDD2 SFT2D1 SYP TMEM239 UBQLN1 UBQLN2 UBQLN4 YIF1A ZNF628	98 interacting genes: ABHD4 AQP6 C6orf47 CMTM3 COQ8A CRB3 CREB3 CYB5R3 CYBRD1 DUSP12 EI24 EMP1 F11R FHIP1B FXR1 FXR2 GDI1 GPR152 HRAS HRG HSD17B13 LEMD3 LMNA LNX1 LTBR MAD2L1 MCF2L MIEF2 NAT14 NDRG2 NDRG4 NIF3L1 NR3C2 NTAQ1 NUDT18 PBX3 PLEKHF2 PLK1 RAB17 RAB1A RAB22A RAB33A RAB3A RAB4A RAB4B RAB5A RAB5B RAB5C RAB6A RAB7A RAP1A RASD2 REEP2 REEP5 RETREG3 RGS2 RHEB RHOA RIC8A RIMS2 RIN3 RNF5 RPS20 RRAS2 S100B SGK1 SH3GL3 SH3GLB1 SLAMF6 SLC10A1 SLC18A1 SNCA SNX1 SNX10 SNX11 SNX15 SNX17 SNX8 SPG21 SSR3 STIM1 STOML2 SYT16 TMEM115 TMEM14B TMEM42 TMX2 TNIP1 TRIM32 TSHR TUBB2A TXN2 UBE2I VAMP2 VIM VTA1 WIPI2 ZFYVE21
Entrez ID		125170	10567
HPRD ID		18074	05375
Ensembl ID		ENSG00000177427	ENSG00000105404
Uniprot IDs		Q96C03	Q9UI14
PDB IDs		5WP9
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Polyubiquitin Modification-dependent Protein Binding Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Organization Regulation Of Proteasomal Protein Catabolic Process Endoplasmic Reticulum Membrane Regulation Of Macroautophagy Autophagosome Positive Regulation Of ERAD Pathway GTP-dependent Protein Binding ERAD Pathway	GTPase Activity GTP Binding GDP Binding Membrane Endosome G Protein Activity Establishment Of Localization In Cell Vesicle-mediated Transport Protein Transport Intracellular Protein Localization Establishment Of Protein Localization Cellular Localization Intracellular Protein Transport Protein Binding Endosomal Transport Regulation Of Neuronal Synaptic Plasticity Lipid Binding Secretory Granule Membrane Intracellular Transport Phosphatidylinositol Binding Endocytosis Vesicle Organization Regulation Of Long-term Neuronal Synaptic Plasticity Early Endosome Regulation Of Cellular Component Organization Endosome Organization Regulation Of Vesicle-mediated Transport Vesicle-mediated Transport In Synapse Synaptic Vesicle Exocytosis Localization Within Membrane Clathrin-sculpted Monoamine Transport Vesicle Membrane Rab Protein Signal Transduction Import Into Cell Early Endosome To Golgi Transport Early Endosome Membrane Endomembrane System Cytoplasmic Vesicle Endoplasmic Reticulum Membrane Organelle Organization Synaptic Vesicle Membrane Identical Protein Binding Autophagosome Assembly Plasma Membrane To Endosome Transport Small GTPase-mediated Signal Transduction Regulation Of Synaptic Plasticity Establishment Of Organelle Localization Autophagosome Organization Endosome Membrane Endocytic Vesicle Organelle Localization
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