MIEF2 and PRB2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MIEF2	PRB2
Description		mitochondrial elongation factor 2	proline rich protein BstNI subfamily 2
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Peroxisome Membrane	Extracellular Region
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Mitochondrion Organization Mitochondrial Fusion Regulation Of Mitochondrion Organization Positive Regulation Of Mitochondrial Fission Positive Regulation Of Protein Targeting To Membrane
Pathways
Drugs
Diseases
GWAS		Change in neurofilament light levels ( 31295725)	Alanine aminotransferase levels ( 33547301) Night sleep phenotypes ( 27126917) Periodontitis (CDC/AAP) ( 24024966) Response to gemcitabine in pancreatic cancer ( 22142827) Survival in pancreatic cancer ( 28470677)
Interacting Genes		30 interacting genes: AGTRAP ARFIP2 ARL6IP1 ATP5PF CIDEA DNM1L FAM114A2 FAM25A FAM25C FAM25G FKBP7 GSG1 HSD17B13 LIME1 MDK NCALD NCS1 PRB2 PSMF1 RABAC1 REEP6 RHBDD2 SFT2D1 SYP TMEM239 UBQLN1 UBQLN2 UBQLN4 YIF1A ZNF628	2 interacting genes: ASPH MIEF2
Entrez ID		125170	653247
HPRD ID		18074
Ensembl ID		ENSG00000177427	ENSG00000121335
Uniprot IDs		Q96C03	P02812
PDB IDs		5WP9
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Polyubiquitin Modification-dependent Protein Binding Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Organization Regulation Of Proteasomal Protein Catabolic Process Endoplasmic Reticulum Membrane Regulation Of Macroautophagy Autophagosome Positive Regulation Of ERAD Pathway GTP-dependent Protein Binding ERAD Pathway	Activation Of Store-operated Calcium Channel Activity Peptidyl-aspartic Acid 3-dioxygenase Activity Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Store-operated Calcium Channel Activity Regulation Of Establishment Of Protein Localization Regulation Of Cellular Localization Cortical Endoplasmic Reticulum Positive Regulation Of Establishment Of Protein Localization Sarcoplasmic Reticulum Lumen Junctional Sarcoplasmic Reticulum Membrane Positive Regulation Of Calcium Ion Transport Into Cytosol Regulation Of Cell Communication By Electrical Coupling Detection Of Calcium Ion Calcium Channel Complex Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Regulation Of Calcium Ion Transport Into Cytosol Regulation Of Protein Localization Positive Regulation Of Cation Channel Activity Positive Regulation Of Protein Targeting To Membrane Positive Regulation Of Mitochondrial Fission Mitochondrial Fusion Response To ATP Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Face Morphogenesis Regulation Of Mitochondrial Fission Regulation Of Protein Targeting To Membrane Positive Regulation Of Ion Transmembrane Transporter Activity Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Positive Regulation Of Transporter Activity Sarcoplasmic Reticulum Membrane Structural Constituent Of Muscle Regulation Of Cytosolic Calcium Ion Concentration Electron Transfer Activity Positive Regulation Of Calcium Ion Transmembrane Transport Sarcoplasmic Reticulum Dioxygenase Activity Regulation Of Transmembrane Transporter Activity Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Roof Of Mouth Development Regulation Of Cardiac Muscle Contraction Cellular Response To Calcium Ion Regulation Of Monoatomic Ion Transmembrane Transporter Activity Regulation Of Protein Depolymerization Positive Regulation Of Intracellular Protein Transport Positive Regulation Of Calcium Ion Transport Regulation Of Striated Muscle Contraction Limb Morphogenesis Detection Of Chemical Stimulus Positive Regulation Of Cation Transmembrane Transport Regulation Of Mitochondrion Organization
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