MIEF2 and FAM25G

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MIEF2	FAM25G
Description		mitochondrial elongation factor 2	family with sequence similarity 25 member G
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Peroxisome Membrane
	Molecular Function	Protein Binding
	Biological Process	Mitochondrion Organization Mitochondrial Fusion Regulation Of Mitochondrion Organization Positive Regulation Of Mitochondrial Fission Positive Regulation Of Protein Targeting To Membrane
Pathways
Drugs
Diseases
GWAS		Change in neurofilament light levels ( 31295725)
Interacting Genes		30 interacting genes: AGTRAP ARFIP2 ARL6IP1 ATP5PF CIDEA DNM1L FAM114A2 FAM25A FAM25C FAM25G FKBP7 GSG1 HSD17B13 LIME1 MDK NCALD NCS1 PRB2 PSMF1 RABAC1 REEP6 RHBDD2 SFT2D1 SYP TMEM239 UBQLN1 UBQLN2 UBQLN4 YIF1A ZNF628	18 interacting genes: ARMC10 ARMCX3 COX16 GPD1 IGLL1 KLHL35 LCN1 LCN2 MIEF1 MIEF2 PPIC PPIF S100A6 SNX1 TDRKH TOMM20L TTPA ZFAND3
Entrez ID		125170	100133093
HPRD ID		18074	19458
Ensembl ID		ENSG00000177427	ENSG00000189090
Uniprot IDs		Q96C03	B3EWG3 B3EWG5 B3EWG6
PDB IDs		5WP9
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Polyubiquitin Modification-dependent Protein Binding Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Organization Regulation Of Proteasomal Protein Catabolic Process Endoplasmic Reticulum Membrane Regulation Of Macroautophagy Autophagosome Positive Regulation Of ERAD Pathway GTP-dependent Protein Binding ERAD Pathway	Mitochondrial Outer Membrane Cyclosporin A Binding Regulation Of Mitochondrion Organization Mitochondrion Mitochondrion Organization Positive Regulation Of Mitochondrial Fission Mitochondrial Fusion Small Molecule Binding Positive Regulation Of Protein Targeting To Membrane Regulation Of Mitochondrial Fission Regulation Of Protein Targeting To Membrane Peptidyl-prolyl Cis-trans Isomerase Activity Glycerol-3-phosphate Dehydrogenase (NAD+) Activity Positive Regulation Of Hippocampal Neuron Apoptotic Process Negative Regulation Of Establishment Of Blood-brain Barrier Regulation Of Proton-transporting ATPase Activity, Rotational Mechanism Glycerol-3-phosphate Dehydrogenase [NAD(P)+] Activity Glycerol-3-phosphate Catabolic Process Glycerol-3-phosphate Shuttle Positive Regulation Of Iron Ion Import Across Plasma Membrane Enterobactin Binding Positive Regulation Of Endothelial Tube Morphogenesis Iron Ion Sequestering Activity Positive Regulation Of Growth Rate TRNA Import Into Mitochondrion Cellular Response To Hydrogen Peroxide
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