SSR1 and NUP54

Number of citations of the paper that reports this interaction (PMID 8707840)
58

Data Source:
HPRD (in vivo)

		SSR1	NUP54
Gene Name		signal sequence receptor, alpha	nucleoporin 54kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Nuclear Envelope Nuclear Pore Nucleoplasm Cytoplasm Nuclear Membrane
	Molecular Function	Protein Binding	Nucleocytoplasmic Transporter Activity
	Biological Process	Translation Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Positive Regulation Of Cell Proliferation Gene Expression Endoplasmic Reticulum Unfolded Protein Response Cellular Protein Metabolic Process	Mitotic Cell Cycle Carbohydrate Metabolic Process Protein Targeting Nucleocytoplasmic Transport Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process MRNA Transport Transmembrane Transport
Pathways		IRE1alpha activates chaperones Translation SRP-dependent cotranslational protein targeting to membrane XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)	Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown SLC-mediated transmembrane transport M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Nuclear Pore Complex (NPC) Disassembly Regulation of Glucokinase by Glucokinase Regulatory Protein Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: DKC1 EEF1A1 HSPA13 NUP54 ODC1 PTN SERPINF2 UTP14A	14 interactors: AP2B1 APC CCDC85B DGCR6 HAUS1 HGS IFT20 KPNA1 KPNB1 KRT15 NUP62 NUPL1 NUTF2 SSR1
Entrez ID		6745	53371
HPRD ID		02924	06352
Ensembl ID		ENSG00000124783	ENSG00000138750
Uniprot IDs		E9PAL7 P43307	B4DT35 Q7Z3B4
PDB IDs
Enriched GO Terms of Interacting Partners?		Putrescine Biosynthetic Process From Ornithine RRNA Processing RRNA Metabolic Process Putrescine Biosynthetic Process Regulation Of Blood Vessel Size By Renin-angiotensin Ribosome Biogenesis Positive Regulation Of Cell Proliferation Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin Ornithine Metabolic Process Negative Regulation Of Plasminogen Activation Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Negative Regulation Of Fibrinolysis	Protein Transport Establishment Of Protein Localization Intracellular Transport Cytoplasmic Transport Protein Localization Nucleocytoplasmic Transport Nuclear Transport Establishment Of Localization In Cell Cellular Localization Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Viral Life Cycle Cellular Protein Localization Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Intracellular Protein Transport Protein Localization To Organelle Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Viral Process Execution Phase Of Apoptosis Regulation Of ERBB Signaling Pathway Establishment Of Protein Localization To Organelle Apoptotic DNA Fragmentation NLS-bearing Protein Import Into Nucleus Protein Targeting Cytokine-mediated Signaling Pathway Intracellular Transport Of Virus Cell Surface Receptor Signaling Pathway Apoptotic Nuclear Changes Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly Cellular Response To Cytokine Stimulus Cellular Response To Organic Substance Mitotic Cell Cycle Process Transport Response To Cytokine Opsin Transport Nuclear Envelope Organization Mitotic Cell Cycle Signal Transduction Glucose Transport Hexose Transport Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Membrane Organization Viral Transcription DNA Catabolic Process, Endonucleolytic Signaling Regulation Of Glucose Transport Negative Regulation Of Intracellular Signal Transduction Cell Communication Response To Organic Substance
Tagcloud ?		3t3 a4 adipocytes antioxidants cyclic cytoprotection dismutase endoplasmic ern1 fabp4 glutathione gmp gsh gsta4 h2o2 kinds l1 lowering nitro orm1 ormdl3 peroxide reticulum scavenger sod spliced superoxide transferase xbp1s
Tagcloud (Difference) ?		3t3 a4 adipocytes antioxidants cyclic cytoprotection dismutase endoplasmic ern1 fabp4 glutathione gmp gsh gsta4 h2o2 kinds l1 lowering nitro orm1 ormdl3 peroxide reticulum scavenger sod spliced superoxide transferase xbp1s
Tagcloud (Intersection) ?