STAG2 and RAD21

Number of citations of the paper that reports this interaction (PMID 15737063)
117

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology)
HPRD (in vivo)

		STAG2	RAD21
Gene Name		stromal antigen 2	RAD21 homolog (S. pombe)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome Nucleolus Cytosol Plasma Membrane Actin Cytoskeleton Membrane Intermediate Filament Cytoskeleton	Chromosome, Centromeric Region Chromatin Nucleoplasm Chromosome Cytosol Cohesin Complex Membrane Nuclear Meiotic Cohesin Complex
	Molecular Function	Chromatin Binding Protein Binding	Protein Binding
	Biological Process	Mitotic Cell Cycle Sister Chromatid Cohesion Mitotic Nuclear Division Stem Cell Maintenance Negative Regulation Of DNA Endoreduplication Cell Division Meiotic Cell Cycle	Mitotic Cell Cycle Double-strand Break Repair DNA Recombination Regulation Of Transcription From RNA Polymerase II Promoter Apoptotic Process Chromosome Segregation Mitotic Nuclear Division Reciprocal Meiotic Recombination Cell Division Protein Localization To Chromatin
Pathways		Establishment of Sister Chromatid Cohesion Mitotic Prometaphase Mitotic Telophase/Cytokinesis Separation of Sister Chromatids Meiotic synapsis Cohesin Loading onto Chromatin Mitotic Anaphase S Phase M Phase Cell Cycle, Mitotic Resolution of Sister Chromatid Cohesion Mitotic Metaphase and Anaphase	Establishment of Sister Chromatid Cohesion Mitotic Prometaphase Mitotic Telophase/Cytokinesis Separation of Sister Chromatids Meiotic synapsis Cohesin Loading onto Chromatin Mitotic Anaphase S Phase M Phase Cell Cycle, Mitotic Resolution of Sister Chromatid Cohesion Mitotic Metaphase and Anaphase
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: PLK1 RAD21 SSU72 STAG1	28 interactors: CAPN1 CASP7 CFL1 COX2 CSTB DISC1 DYNLT1 FHL3 FLNB HNRNPH2 IL7R MSRB2 NUMA1 PPP1R15A PPP1R15B RPL10 RPL13 RPL35A SMARCA5 SMC1A SSU72 STAG1 STAG2 TMSB4X TNFRSF14 WAPAL WNT2B ZNF80
Entrez ID		10735	5885
HPRD ID		05077	05924
Ensembl ID		ENSG00000101972	ENSG00000164754
Uniprot IDs		Q6AI02 Q6MZM3 Q6MZP3 Q8N3U4	O60216
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Localization To Chromatin Chromosome Segregation Protein Localization To Chromosome Mitotic Nuclear Division Cell Division Mitotic Cell Cycle Process Mitotic Cell Cycle Meiotic Nuclear Division Activation Of APC-Cdc20 Complex Activity Cell Cycle Process Meiotic Cell Cycle Dephosphorylation Of RNA Polymerase II C-terminal Domain Polar Body Extrusion After Meiotic Divisions Cell Cycle Negative Regulation Of SMAD Protein Complex Assembly Negative Regulation Of Protein Phosphorylation Activation Of Anaphase-promoting Complex Activity Meiotic Cytokinesis Positive Regulation Of Mitotic Metaphase/anaphase Transition Metaphase/anaphase Transition Of Mitotic Cell Cycle Negative Regulation Of Phosphorylation Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Chromosome Segregation Positive Regulation Of Peptidyl-threonine Phosphorylation Protein Localization To Organelle Protein Destabilization Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity MRNA Polyadenylation G2 DNA Damage Checkpoint Mitotic Spindle Assembly Checkpoint Mitotic Nuclear Envelope Disassembly Female Meiotic Division Spindle Assembly Checkpoint RNA Polyadenylation Mitotic Spindle Checkpoint Negative Regulation Of Cellular Protein Metabolic Process Androgen Receptor Signaling Pathway Positive Regulation Of Mitotic Nuclear Division Negative Regulation Of Chromosome Segregation Nuclear Envelope Disassembly Cellular Response To DNA Damage Stimulus Reciprocal Meiotic Recombination Mitotic Cytokinesis Microtubule Bundle Formation Negative Regulation Of Protein Metabolic Process Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Organelle Organization	Cell Division Mitotic Nuclear Division Cellular Protein Localization Viral Life Cycle Cytoskeleton Organization Mitotic Cell Cycle Process Negative Regulation Of DNA Endoreduplication Protein Localization To Endoplasmic Reticulum Cell Cycle Process Mitotic Cell Cycle Organelle Organization Protein Localization To Organelle Negative Regulation Of DNA Replication MRNA Metabolic Process Viral Process Protein Localization Cellular Localization Cellular Protein Complex Disassembly Regulation Of DNA Endoreduplication Protein Complex Disassembly Cell Cycle Negative Regulation Of Cell Cycle Viral Transcription Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay SRP-dependent Cotranslational Protein Targeting To Membrane Establishment Of Cell Polarity Negative Regulation Of DNA Metabolic Process Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Regulation Of DNA Replication Sister Chromatid Cohesion Establishment Of Mitotic Spindle Orientation Actin Cytoskeleton Organization Translational Termination Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Establishment Of Protein Localization To Organelle Nuclear-transcribed MRNA Catabolic Process Actin Filament-based Process MRNA Catabolic Process Protein Targeting To Membrane Establishment Or Maintenance Of Cell Polarity Viral Entry Into Host Cell Translational Elongation Spindle Localization Regulation Of Metabolic Process Entry Into Host Cell RNA Catabolic Process Positive Regulation Of Translational Initiation In Response To Stress
Tagcloud ?		aml antecedent asxl1 bcor clinicopathologic clonal de define highlights identifiable leukemogenesis leukemogenic malignancy mutational myeloid novo persist prodrome remissions rigorously serial sf3b1 shares srsf2 subset u2af1 unselected worse zrsr2	aberrations apart aspect ccnd1 clinicopathological copy covered encompassed endometrial erbb1 erbb2 erbb3 erbb4 esr1 frequent infiltration insufficient myometrial pakt1 pgr pik3ca prom1 rad27 runx1 scgb2a2 snai1 snai2 top2a younger
Tagcloud (Difference) ?		aml antecedent asxl1 bcor clinicopathologic clonal de define highlights identifiable leukemogenesis leukemogenic malignancy mutational myeloid novo persist prodrome remissions rigorously serial sf3b1 shares srsf2 subset u2af1 unselected worse zrsr2	aberrations apart aspect ccnd1 clinicopathological copy covered encompassed endometrial erbb1 erbb2 erbb3 erbb4 esr1 frequent infiltration insufficient myometrial pakt1 pgr pik3ca prom1 rad27 runx1 scgb2a2 snai1 snai2 top2a younger
Tagcloud (Intersection) ?