STAG2

Gene Name		stromal antigen 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome Nucleolus Cytosol Plasma Membrane Actin Cytoskeleton Membrane Intermediate Filament Cytoskeleton
	Molecular Function	Chromatin Binding Protein Binding
	Biological Process	Mitotic Cell Cycle Sister Chromatid Cohesion Mitotic Nuclear Division Stem Cell Maintenance Negative Regulation Of DNA Endoreduplication Cell Division Meiotic Cell Cycle
Pathways		Establishment of Sister Chromatid Cohesion Mitotic Prometaphase Mitotic Telophase/Cytokinesis Separation of Sister Chromatids Meiotic synapsis Cohesin Loading onto Chromatin Mitotic Anaphase S Phase M Phase Cell Cycle, Mitotic Resolution of Sister Chromatid Cohesion Mitotic Metaphase and Anaphase
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: PLK1 RAD21 SSU72 STAG1
Entrez ID		10735
HPRD ID		05077
Ensembl ID		ENSG00000101972
Uniprot IDs		Q6AI02 Q6MZM3 Q6MZP3 Q8N3U4
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Localization To Chromatin Chromosome Segregation Protein Localization To Chromosome Mitotic Nuclear Division Cell Division Mitotic Cell Cycle Process Mitotic Cell Cycle Meiotic Nuclear Division Activation Of APC-Cdc20 Complex Activity Cell Cycle Process Meiotic Cell Cycle Dephosphorylation Of RNA Polymerase II C-terminal Domain Polar Body Extrusion After Meiotic Divisions Cell Cycle Negative Regulation Of SMAD Protein Complex Assembly Negative Regulation Of Protein Phosphorylation Activation Of Anaphase-promoting Complex Activity Meiotic Cytokinesis Positive Regulation Of Mitotic Metaphase/anaphase Transition Metaphase/anaphase Transition Of Mitotic Cell Cycle Negative Regulation Of Phosphorylation Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Chromosome Segregation Positive Regulation Of Peptidyl-threonine Phosphorylation Protein Localization To Organelle Protein Destabilization Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity MRNA Polyadenylation G2 DNA Damage Checkpoint Mitotic Spindle Assembly Checkpoint Mitotic Nuclear Envelope Disassembly Female Meiotic Division Spindle Assembly Checkpoint RNA Polyadenylation Mitotic Spindle Checkpoint Negative Regulation Of Cellular Protein Metabolic Process Androgen Receptor Signaling Pathway Positive Regulation Of Mitotic Nuclear Division Negative Regulation Of Chromosome Segregation Nuclear Envelope Disassembly Cellular Response To DNA Damage Stimulus Reciprocal Meiotic Recombination Mitotic Cytokinesis Microtubule Bundle Formation Negative Regulation Of Protein Metabolic Process Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Organelle Organization
Tagcloud ?		aml antecedent asxl1 bcor clinicopathologic clonal de define highlights identifiable leukemogenesis leukemogenic malignancy mutational myeloid novo persist prodrome remissions rigorously serial sf3b1 shares srsf2 subset u2af1 unselected worse zrsr2