STAG2 and SSU72

Number of citations of the paper that reports this interaction (PMID 20818333)
3

Data Source:
BioGRID (enzymatic study)

		STAG2	SSU72
Gene Name		stromal antigen 2	SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome Nucleolus Cytosol Plasma Membrane Actin Cytoskeleton Membrane Intermediate Filament Cytoskeleton	Nucleus Cytoplasm
	Molecular Function	Chromatin Binding Protein Binding	Protein Binding CTD Phosphatase Activity
	Biological Process	Mitotic Cell Cycle Sister Chromatid Cohesion Mitotic Nuclear Division Stem Cell Maintenance Negative Regulation Of DNA Endoreduplication Cell Division Meiotic Cell Cycle	MRNA Polyadenylation Dephosphorylation Of RNA Polymerase II C-terminal Domain
Pathways		Establishment of Sister Chromatid Cohesion Mitotic Prometaphase Mitotic Telophase/Cytokinesis Separation of Sister Chromatids Meiotic synapsis Cohesin Loading onto Chromatin Mitotic Anaphase S Phase M Phase Cell Cycle, Mitotic Resolution of Sister Chromatid Cohesion Mitotic Metaphase and Anaphase
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: PLK1 RAD21 SSU72 STAG1	5 interactors: MAPK8 MAPK9 RAD21 STAG2 SYMPK
Entrez ID		10735	29101
HPRD ID		05077	13712
Ensembl ID		ENSG00000101972	ENSG00000160075
Uniprot IDs		Q6AI02 Q6MZM3 Q6MZP3 Q8N3U4	Q9NP77
PDB IDs			3O2Q 3O2S 4H3H 4H3K
Enriched GO Terms of Interacting Partners?		Protein Localization To Chromatin Chromosome Segregation Protein Localization To Chromosome Mitotic Nuclear Division Cell Division Mitotic Cell Cycle Process Mitotic Cell Cycle Meiotic Nuclear Division Activation Of APC-Cdc20 Complex Activity Cell Cycle Process Meiotic Cell Cycle Dephosphorylation Of RNA Polymerase II C-terminal Domain Polar Body Extrusion After Meiotic Divisions Cell Cycle Negative Regulation Of SMAD Protein Complex Assembly Negative Regulation Of Protein Phosphorylation Activation Of Anaphase-promoting Complex Activity Meiotic Cytokinesis Positive Regulation Of Mitotic Metaphase/anaphase Transition Metaphase/anaphase Transition Of Mitotic Cell Cycle Negative Regulation Of Phosphorylation Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Chromosome Segregation Positive Regulation Of Peptidyl-threonine Phosphorylation Protein Localization To Organelle Protein Destabilization Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity MRNA Polyadenylation G2 DNA Damage Checkpoint Mitotic Spindle Assembly Checkpoint Mitotic Nuclear Envelope Disassembly Female Meiotic Division Spindle Assembly Checkpoint RNA Polyadenylation Mitotic Spindle Checkpoint Negative Regulation Of Cellular Protein Metabolic Process Androgen Receptor Signaling Pathway Positive Regulation Of Mitotic Nuclear Division Negative Regulation Of Chromosome Segregation Nuclear Envelope Disassembly Cellular Response To DNA Damage Stimulus Reciprocal Meiotic Recombination Mitotic Cytokinesis Microtubule Bundle Formation Negative Regulation Of Protein Metabolic Process Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Organelle Organization	JUN Phosphorylation Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Response To Cadmium Ion Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway JNK Cascade Regulation Of Circadian Rhythm Toll-like Receptor Signaling Pathway Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Response To UV Activation Of Innate Immune Response Cellular Response To Lipopolysaccharide Cellular Response To Molecule Of Bacterial Origin Positive Regulation Of Innate Immune Response Apoptotic Process Positive Regulation Of Apoptotic Signaling Pathway Programmed Cell Death Meiotic Cell Cycle Cell Death Response To Mechanical Stimulus Death MAPK Cascade Fc-epsilon Receptor Signaling Pathway Chromosome Segregation Negative Regulation Of DNA Endoreduplication Regulation Of Innate Immune Response Positive Regulation Of Deacetylase Activity Positive Regulation Of Prostaglandin Biosynthetic Process Fc Receptor Signaling Pathway Signal Transduction By Phosphorylation Positive Regulation Of Determination Of Dorsal Identity Response To Lipopolysaccharide Mitotic Nuclear Division Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Metal Ion Response To Molecule Of Bacterial Origin Response To Light Stimulus Apoptotic Signaling Pathway Regulation Of DNA Endoreduplication
Tagcloud ?		aml antecedent asxl1 bcor clinicopathologic clonal de define highlights identifiable leukemogenesis leukemogenic malignancy mutational myeloid novo persist prodrome remissions rigorously serial sf3b1 shares srsf2 subset u2af1 unselected worse zrsr2	alleles choose cleavage conversely degrades disrupt elongation exonuclease exosome generates keeps localize nrd1 nucleolar options pcf11 poly polyadenylated polyadenylation rat1 rnas sen1 snorna snornas termination transcribed transcribing trimming xrn2
Tagcloud (Difference) ?		aml antecedent asxl1 bcor clinicopathologic clonal de define highlights identifiable leukemogenesis leukemogenic malignancy mutational myeloid novo persist prodrome remissions rigorously serial sf3b1 shares srsf2 subset u2af1 unselected worse zrsr2	alleles choose cleavage conversely degrades disrupt elongation exonuclease exosome generates keeps localize nrd1 nucleolar options pcf11 poly polyadenylated polyadenylation rat1 rnas sen1 snorna snornas termination transcribed transcribing trimming xrn2
Tagcloud (Intersection) ?